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Validation of the Portuguese version of the quality of life questionnaire of the European foundation for osteoporosis (QUALEFFO-41) in Brazilian women with postmenopausal osteoporosis with vertebral fracture

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Abstract

To validate the Portuguese version of the quality of life questionnaire of the European foundation for osteoporosis (QUALEFFO-41) in Brazilian women with osteoporotic vertebral fractures (VF). A questionnaire validation study of 86 postmenopausal women was conducted. Women were divided into two groups: 43 in a group with VF and 43 in a group without osteoporosis, age-matched (±3 years). The QUALEFFO-41 questionnaire was administered twice in 4 weeks and compared to a generic questionnaire SF-36. For analysis of the QUALEFFO-41, internal consistency, repeatability, and discriminant capacity between VF patients and control patients were assessed. The significance level adopted was 5 %. The mean age of the women was 66.1 ± 7.2 years for the group with VF and 64.9 ± 6.3 years for the control group (p = 0.4259). The QUALEFFO showed adequate internal consistency in all domains (Cronbach's α of 0.74 to 0.84) and good repeatability (ICC of domains = 0.67–0.90). Of the total questions, 92.6 % demonstrated satisfactory convergent validity, and 95 % of the questions showed good discriminant validity. The mean scores of both questionnaires were significantly higher in the group with VF. There was a good correlation among the QUALEFFO-41 domains and their corresponding SF-36 domains, except for social function. All QUALEFFO-41 domains were significantly predictive of VF on assessment of the ROC curve. The Portuguese version of the QUALEFFO-41 may be used in Brazilian women with osteoporotic VF because it shows good reliability, repeatability, and validity. It was also shown to impair quality of life (QOL) in women with VF and had good ability to discriminate QOL in women with osteoporotic VF.

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Acknowledgments

The authors would like to thank Fundo de Apoio ao Ensino e a Pesquisa(FAEPEX)—Unicamp (Process number 237/07 and 168/09) for providing financial support for the project. We also wish to thank the Radiology Division, in special thanks to Dr Nelson Caserta, for facilitating the performance of X-rays in the patients studied, the team of rheumatology outpatient facility of the Clinics Hospital (in special to Dr João Francisco Marques Neto), and the team of gynecologists and physical therapists at Women's Integrated Healthcare Center (CAISM) for making space available to carry out the study.

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Authors and Affiliations

  1. Women’s Integrated Healthcare Center (CAISM), Universidade Estadual de Campinas (Unicamp), São Paulo, Brazil

    Néville de Oliveira Ferreira

  2. Unicamp School of Medicine, São Paulo, Brazil

    Michael Arthuso

  3. Universidade Estadual de Maringá (UEM), Paraná, Brazil

    Raimunda Beserra da Silva

  4. Department of Obstetrics and Gynecology, Unicamp, School of Medicine, Rua Alexander Fleming, 101, Cidade Universitária, Campinas, 13083-330, São Paulo, Brazil

    Aarão Mendes Pinto-Neto & Lúcia Costa-Paiva

Authors
  1. Néville de Oliveira Ferreira
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  2. Michael Arthuso
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  3. Raimunda Beserra da Silva
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  4. Aarão Mendes Pinto-Neto
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  5. Lúcia Costa-Paiva
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Correspondence to Lúcia Costa-Paiva.

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de Oliveira Ferreira, N., Arthuso, M., da Silva, R.B. et al. Validation of the Portuguese version of the quality of life questionnaire of the European foundation for osteoporosis (QUALEFFO-41) in Brazilian women with postmenopausal osteoporosis with vertebral fracture. Clin Rheumatol 32, 1585–1592 (2013). https://doi.org/10.1007/s10067-013-2265-8

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