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Regional migratory osteoporosis and transient osteoporosis of the hip: are they all the same?

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Abstract

We hypothesized that regional migratory osteoporosis (RMO) and transient osteoporosis of the hip (TOH) terms describe a common disease process. Therefore, based on our patient, we aimed to review the pathogenesis, diagnosis, and treatment of both diseases. The patient was a pregnant woman in her third trimester with sacral insufficiency fracture, which was shortly followed by migratory arthralgia of both hips and ankles in a proximal to distal direction. She was operated (core decompression) for both hips and ankles, and she was symptom free at 17th month. RMO and TOH have an unclear etiology, share the similar course, and bear a self-limiting nature. Both disorders may be the same clinical entity with a common pathogenesis. Probably, many of RMO patients were labeled as TOH, and therefore, RMO has been underrepresented. In conclusion, we think that both RMO and TOH describe a common disease process. Either the diagnosis is RMO or TOH, the management will be the same. Finally, the conservative treatment protocol is a better treatment modality and must be obeyed even in resistant cases.

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References

  1. Duncan H, Frame B, Frost HM, Arnstein AR (1967) Migratory osteolysis of the lower extremities. Ann Intern Med 66(6):1165–1173

    Article  PubMed  CAS  Google Scholar 

  2. Toms AP, Marshall TJ, Becker E et al (2005) Regional migratory osteoporosis: a review illustrated by five cases. Clin Radiol 60(4):425–438. doi:10.1016/j.crad.2004.07.002

    Article  PubMed  CAS  Google Scholar 

  3. Trevisan C, Ortolani S, Monteleone M, Marinoni EC (2002) Regional migratory osteoporosis: a pathogenetic hypothesis based on three cases and a review of the literature. Clin Rheumatol 21(5):418–425. doi:10.1007/s100670200112

    Article  PubMed  CAS  Google Scholar 

  4. Malizos KN, Zibis AH, Dailiana Z et al (2004) MR imaging findings in transient osteoporosis of the hip. Eur J Radiol 50(3):238–244. doi:10.1016/j.ejrad.2004.01.020

    Article  PubMed  Google Scholar 

  5. Shifrin L, Reis ND, Zinman H, Besser MI (1987) Idiopathic transient osteoporosis of the hip. J Bone Joint Surg Br 69(5):769–773

    PubMed  CAS  Google Scholar 

  6. Mavichack V, Murray TM, Hodsman AB, Robert NJ, Sutton RAL (1986) Regional migratory osteoporosis of the lower extremities with vertebral osteoporosis. Bone 7:343–349. doi:10.1016/8756-3282(86)90254-1

    Article  Google Scholar 

  7. Curtiss PH Jr, Kincaid WE (1959) Transitory demineralization of the hip in pregnancy. A report of three cases. Am J Orthop 41-A:1327–1333

    Google Scholar 

  8. Ma FY, Falkenberg M (2006) Case reports: transient osteoporosis of the hip: an atypical case. Clin Orthop Relat Res 445:245–249

    PubMed  Google Scholar 

  9. Potter H, Moran M, Schneider R et al (1992) Magnetic resonance imaging in diagnosis of transient osteoporosis of the hip. Clin Orthop Relat Res 280:223–229. doi:10.1097/00003086-199207000-00029

    PubMed  Google Scholar 

  10. Cahir JG, Toms AP (2008) Regional migratory osteoporosis. Eur J Radiol 67(1):2–10. doi:10.1016/j.ejrad.2008.01.051

    Article  PubMed  Google Scholar 

  11. Frost HM (1992) Perspectives: bone’s mechanical usage windows. Bone Miner 19(3):257–271. doi:10.1016/0169-6009(92)90875-E

    Article  PubMed  CAS  Google Scholar 

  12. Frost HM (1989) The biology of fracture healing. An overview for clinicians. Part I. Clin Orthop Relat Res 248:283–293. doi:10.1097/00003086-198911000-00045

    PubMed  Google Scholar 

  13. Aigner N, Meizer R, Stolz G et al (2003) Iloprost for the treatment of bone marrow edema in the hindfoot. Foot Ankle Clin 8(4):683–693. doi:10.1016/S1083-7515(03)00145-1

    Article  PubMed  CAS  Google Scholar 

  14. Gruber HE, Gutteridge DH, Baylink DJ (1984) Osteoporosis associated with pregnancy and lactation: bone biopsy and skeletal features in three patients. Metabol Bone Dis Rel Res 5:159–165. doi:10.1016/0221-8747(84)90023-7

    Article  CAS  Google Scholar 

  15. Peters FP, Verhoeven MA, Anten HW, Erdkamp FL, van der Pol H (2002) Reversible migratory osteoporosis in renal oncocytoma mimicking renal cell carcinoma with bone metastases. Neth J Med 60(10):411–413

    PubMed  CAS  Google Scholar 

  16. Carty S, Herdman G, Williams F, Srinivasan U (2007) Transient migratory osteoporosis: rapid response to pamidronate treatment. J Clin Rheumatol 13(3):138–139. doi:10.1097/RHU.0b013e318064e78d

    Article  PubMed  Google Scholar 

  17. Davis KW (2009) Transient migratory osteoporosis or insufficiency fracture? J Clin Rheumatol 15(3):153. doi:10.1097/RHU.0b013e3181a39b2f

    Article  PubMed  Google Scholar 

  18. Hofmann S, Engel A, Neuhold A et al (1993) Bone marrow oedema syndrome and transient osteoporosis of the hip. An MRI controlled study of treatment by core decompression. J Bone Joint Surg Br 75(2):210–216

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Orthopaedics and Traumatology Department, Acibadem Maslak Hospital, Istanbul, Turkey

    Metin Uzun

  2. Orthopaedics and Traumatology Department, Gelibolu Public Hospital, Gelibolu, Canakkale, Turkey

    Egemen Ayhan

  3. Orthopaedics and Traumatology Department, Acibadem University Medical School, Istanbul, Turkey

    Burak Beksac

  4. Orthopaedics and Traumatology Department, Fatih Sultan Mehmet Research and Training Hospital, Istanbul, Turkey

    Özgür Karaman

Authors
  1. Metin Uzun
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  2. Egemen Ayhan
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  3. Burak Beksac
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  4. Özgür Karaman
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Correspondence to Egemen Ayhan.

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Uzun, M., Ayhan, E., Beksac, B. et al. Regional migratory osteoporosis and transient osteoporosis of the hip: are they all the same?. Clin Rheumatol 32, 919–923 (2013). https://doi.org/10.1007/s10067-013-2243-1

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  • DOI: https://doi.org/10.1007/s10067-013-2243-1

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