Abstract
Suicide and suicidal behaviors represent a leading cause of morbidity and mortality during adolescence. While several lines of evidence suggest that suicidal behaviors are associated with risky decisions and deficient cognitive control in laboratory tasks in adults, comparatively less is known about adolescents. Here, we systematically reviewed the literature on the association between these neurocognitive variables and adolescent suicidal behaviors. The online search strategy identified 17 neurocognitive studies examining either cognitive control or decision-making processes in adolescents with past suicidal behaviors. Several studies have reported that adolescents with a history of suicidal behaviors present neuropsychological differences in the cognitive control (using Go/NoGo, suicide Stroop Test, continuous performance test, suicide/death Implicit Association Test), and decision-making (Iowa Gambling Task, Cambridge Gambling Task, cost computation, delay discounting, loss aversion tasks) domains. Due to a lack of replication or conflicting findings, our systematic review suggests that no firm conclusion can be drawn as to whether altered decision-making or poor cognitive control contribute to adolescent suicidal behaviors. However, these results collectively suggest that further research is warranted. Limitations included scarcity of longitudinal studies and a lack of homogeneity in study designs, which precluded quantitative analysis. We propose remediating ways to continue neuropsychological investigations of suicide risk in adolescence, which could lead to the identification of novel therapeutic targets and predictive markers, enabling early intervention in suicidal youth.
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References
CDC (2015) Definitions: self-directed violence. Center of Disease Control and Prevention. https://www.cdc.gov/violenceprevention/suicide/definitions.html.
Silverman MM, Berman AL, Sanddal ND, O’Carroll PW, Joiner TE Jr (2007) Rebuilding the tower of babel—a revised nomenclature for the study of suicide and suicidal behaviors part 2—suicide-related ideations, communications, and behaviors. Suicide Life-Threatening Behavior 37(3):264–277
Nock MK, Green JG, Hwang I, McLaughlin KA, Sampson NA, Zaslavsky AM, Kessler RC (2013) Prevalence, correlates, and treatment of lifetime suicidal behavior among adolescents: results from the national comorbidity survey replication adolescent supplement. JAMA Psychiatry 70(3):300–310. https://doi.org/10.1001/2013.jamapsychiatry.55
Kann L, McManus T, Harris WA, Shanklin SL, Flint KH, Queen B, Lowry R, Chyen D, Whittle L, Thornton J, Lim C, Bradford D, Yamakawa Y, Leon M, Brener N, Ethier KA (2018) Youth Risk Behavior Surveillance—United States, 2017. MMWR Surveillance Summaries, vol 67. Atlanta, GA
Mokdad AH, Forouzanfar MH, Daoud F, Mokdad AA, El Bcheraoui C, Moradi-Lakeh M, Kyu HH, Barber RM, Wagner J, Cercy K, Kravitz H, Coggeshall M, Chew A, O'Rourke KF, Steiner C, Tuffaha M, Charara R, Al-Ghamdi EA, Adi Y, Afifi RA, Alahmadi H, AlBuhairan F, Allen N, AlMazroa M, Al-Nehmi AA, AlRayess Z, Arora M, Azzopardi P, Barroso C, Basulaiman M, Bhutta ZA, Bonell C, Breinbauer C, Degenhardt L, Denno D, Fang J, Fatusi A, Feigl AB, Kakuma R, Karam N, Kennedy E, Khoja TA, Maalouf F, Obermeyer CM, Mattoo A, McGovern T, Memish ZA, Mensah GA, Patel V, Petroni S, Reavley N, Zertuche DR, Saeedi M, Santelli J, Sawyer SM, Ssewamala F, Taiwo K, Tantawy M, Viner RM, Waldfogel J, Zuniga MP, Naghavi M, Wang H, Vos T, Lopez AD, Al Rabeeah AA, Patton GC, Murray CJ (2016) Global burden of diseases, injuries, and risk factors for young people's health during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 387(10036):2383–2401. https://doi.org/10.1016/S0140-6736(16)00648-6
Patton GC, Sawyer SM, Santelli JS, Ross DA, Afifi R, Allen NB, Arora M, Azzopardi P, Baldwin W, Bonell C, Kakuma R, Kennedy E, Mahon J, McGovern T, Mokdad AH, Patel V, Petroni S, Reavley N, Taiwo K, Waldfogel J, Wickremarathne D, Barroso C, Bhutta Z, Fatusi AO, Mattoo A, Diers J, Fang J, Ferguson J, Ssewamala F, Viner RM (2016) Our future: a Lancet commission on adolescent health and wellbeing. The Lancet 387(10036):2423–2478. https://doi.org/10.1016/s0140-6736(16)00579-1
Oquendo MA (2014) Suicidal behavior: strategies for prevention at the individual and population levels. The Journal of clinical psychiatry 75(8):877–878. https://doi.org/10.4088/JCP.14f09366
Franklin JC, Ribeiro JD, Fox KR, Bentley KH, Kleiman EM, Huang X, Musacchio KM, Jaroszewski AC, Chang BP, Nock MK (2017) Risk factors for suicidal thoughts and behaviors: a meta-analysis of 50 years of research. Psychol Bull 143(2):187–232. https://doi.org/10.1037/bul0000084
Klonsky ED, May A (2010) Rethinking impulsivity in suicide. Suicide Life-Threatening Behavior 40(6):612–619
May AM, Klonsky ED (2016) What distinguishes suicide attempters from suicide ideators? A meta-analysis of potential factors. Clin Psychol Sci Pract 23(1):5–20. https://doi.org/10.1111/cpsp.12136
Klonsky ED, May AM, Saffer BY (2016) Suicide, Suicide Attempts, And Suicidal Ideation. Annu Rev Clin Psychol 12:307–330. https://doi.org/10.1146/annurev-clinpsy-021815-093204
Glenn CR, Cha CB, Kleiman EM, Nock MK (2017) Understanding suicide risk within the research domain criteria (RDoC) framework: insights, challenges, and future research considerations. Clin Psychol Sci 5(3):568–592. https://doi.org/10.1177/2167702616686854
Yip SW, Potenza MN (2018) Application of research domain criteria to childhood and adolescent impulsive and addictive disorders: implications for treatment. Clin Psychol Rev 64:41–56. https://doi.org/10.1016/j.cpr.2016.11.003
Casey BJ, Oliveri ME, Insel T (2014) A neurodevelopmental perspective on the research domain criteria (RDoC) framework. Biol Psychiatry 76(5):350–353. https://doi.org/10.1016/j.biopsych.2014.01.006
Jankowski MK, Rosenberg HJ, Sengupta A, Rosenberg SD, Wolford GL (2007) Development of a screening tool to identify adolescents engaged in multiple problem behaviors: the Adolescent Risk Behavior Screen (ARBS). J Adolesc Health 40(2):180. https://doi.org/10.1016/j.jadohealth.2006.09.016
SAMHSA (2017) National survey on drug use and health. Rockville, MD
Makikyro TH, Hakko HH, Timonen MJ, Lappalainen JA, Ilomaki RS, Marttunen MJ, Laksy K, Rasanen PK (2004) Smoking and suicidality among adolescent psychiatric patients. J Adolesc Health 34(3):250–253. https://doi.org/10.1016/j.jadohealth.2003.06.008
Wang PW, Yen CF (2017) Adolescent substance use behavior and suicidal behavior for boys and girls: a cross-sectional study by latent analysis approach. BMC Psychiatry 17(1):392. https://doi.org/10.1186/s12888-017-1546-1
Garrison CZ, McKeown RE, Valois RF, Vincent ML (1993) Aggression, substance use, and suicidal behaviors in high school students. Am J Public Health 82(2):179–184
Miller TR, Taylor DM (2005) Adolescent suicidality who will ideate, who will act? Suicide Life-Threatening Behavior 35(4):425–435
Spear LP (2000) The adolescent brain and age-related behavioral manifestations. Neurosci Biobehav Rev 24:417–463
Dahl RE (2004) Adolescent brain development: a period of vulnerabilities and opportunities. Keynote address. Ann N Y Acad Sci 6(1021):1–22
Blakemore SJ, Robbins TW (2012) Decision-making in the adolescent brain. Nat Neurosci 15(9):1184–1191. https://doi.org/10.1038/nn.3177
Casey BJ, Galvan A, Somerville LH (2016) Beyond simple models of adolescence to an integrated circuit-based account: a commentary. Dev Cogn Neurosci 17:128–130. https://doi.org/10.1016/j.dcn.2015.12.006
Luna B (2009) Developmental changes in cognitive control through adolescence. Adv Child Dev Behav 37:233–278
Casey BJ (2015) Beyond simple models of self-control to circuit-based accounts of adolescent behavior. Annu Rev Psychol 66:295–319. https://doi.org/10.1146/annurev-psych-010814-015156
Jollant F, Lawrence NL, Olie E, Guillaume S, Courtet P (2011) The suicidal mind and brain: a review of neuropsychological and neuroimaging studies. World J Biol Psychiatry 12(5):319–339. https://doi.org/10.3109/15622975.2011.556200
Dombrovski AY, Hallquist MN (2017) The decision neuroscience perspective on suicidal behavior: evidence and hypotheses. Curr Opin Psychiatry 30(1):7–14. https://doi.org/10.1097/YCO.0000000000000297
Jollant F, Bellivier F, Leboyer M, Astruc B, Torres S, Verdier R, Castelnau D, Malafosse A, Courtet P (2005) Impaired decision making in suicide attempters. Am J Psychiatry 162:304–310
Clark L, Dombrovski AY, Siegle GJ, Butters MA, Shollenberger CL, Sahakian BJ, Szanto K (2011) Impairment in risk-sensitive decision-making in older suicide attempters with depression. Psychol Aging 26(2):321–330. https://doi.org/10.1037/a0021646
Richard-Devantoy S, Berlim MT, Jollant F (2013) A meta-analysis of neuropsychological markers of vulnerability to suicidal behavior in mood disorders. Psychol Med 44(08):1663–1673. https://doi.org/10.1017/s0033291713002304
Jollant F, Lawrence NS, Olie E, O'Daly O, Malafosse A, Courtet P, Phillips ML (2010) Decreased activation of lateral orbitofrontal cortex during risky choices under uncertainty is associated with disadvantageous decision-making and suicidal behavior. Neuroimage 51(3):1275–1281. https://doi.org/10.1016/j.neuroimage.2010.03.027
Dombrovski AY, Szanto K, Clark L, Reynolds CF, Siegle GJ (2013) Reward signals, attempted suicide, and impulsivity in late-life depression. JAMA Psychiatry 70(10):1. https://doi.org/10.1001/jamapsychiatry.2013.75
Olie E, Seyller M, Beziat S, Loftus J, Bellivier F, Bougerol T, Belzeaux R, Azorin JM, Gard S, Kahn JP, Passerieux C, Leboyer M, Etain B, Henry C, Courtet P (2015) Clinical and neuropsychological characteristics of euthymic bipolar patients having a history of severe suicide attempt. Acta Psychiatr Scand 131(2):129–138. https://doi.org/10.1111/acps.12326
Hoehne A, Richard-Devantoy S, Ding Y, Turecki G, Jollant F (2015) First-degree relatives of suicide completers may have impaired decision-making but functional cognitive control. J Psychiatr Res 68:192–197. https://doi.org/10.1016/j.jpsychires.2015.07.004
Ding Y, Pereira F, Hoehne A, Beaulieu MM, Lepage M, Turecki G, Jollant F (2017) Altered brain processing of decision-making in healthy first-degree biological relatives of suicide completers. Mol Psychiatry 22(8):1149–1154. https://doi.org/10.1038/mp.2016.221
Wong PW, Cheung DY, Conner KR, Conwell Y, Yip PS (2010) Gambling and completed suicide in Hong Kong: a review of coroner court files. Primary care Companion J Clin Psychiatry 12:6. https://doi.org/10.4088/PCC.09m00932blu
Vijayakumar L, Kumar MS, Vijayakumar V (2011) Substance use and suicide. Curr Opin Psychiatry 24(3):197–202. https://doi.org/10.1097/YCO.0b013e3283459242
Richard-Devantoy S, Gorwood P, Annweiler C, Olié J-P, Le Gall D, Beauchet O (2012) Suicidal behaviours in affective disorders—a deficit of cognitive inhibition? Can J Psychiatry Revue 57(4):254–262
Keilp JG, Gorlyn M, Russell M, Oquendo MA, Burke AK, Harkavy-Friedman J, Mann JJ (2013) Neuropsychological function and suicidal behavior: attention control, memory and executive dysfunction in suicide attempt. Psychol Med 43(3):539–551. https://doi.org/10.1017/S0033291712001419
Richard-Devantoy S, Olie E, Guillaume S, Bechara A, Courtet P, Jollant F (2013) Distinct alterations in value-based decision-making and cognitive control in suicide attempters: toward a dual neurocognitive model. J Affect Disord 151(3):1120–1124. https://doi.org/10.1016/j.jad.2013.06.052
Richard-Devantoy S, Ding Y, Lepage M, Turecki G, Jollant F (2016) Cognitive inhibition in depression and suicidal behavior: a neuroimaging study. Psychol Med 46(5):933–944. https://doi.org/10.1017/S0033291715002421
Cullen B, Ward J, Graham NA, Deary IJ, Pell JP, Smith DJ, Evans JJ (2016) Prevalence and correlates of cognitive impairment in euthymic adults with bipolar disorder: a systematic review. J Affect Disord 205:165–181. https://doi.org/10.1016/j.jad.2016.06.063
Wilcox CE, Dekonenko CJ, Mayer AR, Bogenschutz MP, Turner JA (2014) Cognitive control in alcohol use disorder: deficits and clinical relevance. Rev Neurosci 25(1):1–24. https://doi.org/10.1515/revneuro-2013-0054
Enticott PG, Ogloff JRP, Bradshaw JL (2006) Associations between laboratory measures of executive inhibitory control and self-reported impulsivity. Pers Individ Dif 41:285–294. https://doi.org/10.1016/j.paid.2006.01.011
Joorman J, Yoon KL, Zetsche U (2007) Cognitive inhibition in depression. Appl Prev Psychol 12:128–139. https://doi.org/10.1016/j.appsy.2007.09.002
Field M, Wiers RW, Christiansen P, Fillmore MT, Verster JC (2010) Acute alcohol effects on inhibitory control and implicit cognition: implications for loss of control over drinking. Alcohol Clin Exp Res 34(8):1346–1352. https://doi.org/10.1111/j.1530-0277.2010.01218.x
Shields GS, Sazma MA, Yonelinas AP (2016) The effects of acute stress on core executive functions: a meta-analysis and comparison with cortisol. Neurosci Biobehav Rev 68:651–668. https://doi.org/10.1016/j.neubiorev.2016.06.038
Reynolds BW, Basso MR, Miller AK, Whiteside DM, Combs D (2018) Executive function, impulsivity, and risky behaviors in young adults. Neuropsychology. https://doi.org/10.1037/neu0000510
Miyake A, Friedman NP, Emerson MJ, Witzki AH, Howerter A, Wager TD (2000) The unity and diversity of executive functions and their contributions to complex "Frontal Lobe" tasks: a latent variable analysis. Cogn Psychol 41(1):49–100. https://doi.org/10.1006/cogp.1999.0734
Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS medicine 6(7):e1000100. https://doi.org/10.1371/journal.pmed.1000100
Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011] (2011) The Cochrane Collaboration
Dougherty DM, Mathias CW, Marsh-Richard DM, Prevette KN, Dawes MA, Hatzis ES, Palmes G, Nouvion SO (2009) Impulsivity and clinical symptoms among adolescents with non-suicidal self-injury with or without attempted suicide. Psychiatry Res 169(1):22–27. https://doi.org/10.1016/j.psychres.2008.06.011
Miller M, Nevado-Montenegro AJ, Hinshaw SP (2012) Childhood executive function continues to predict outcomes in young adult females with and without childhood-diagnosed ADHD. J Abnorm Child Psychol 40(5):657–668. https://doi.org/10.1007/s10802-011-9599-y
Mathias CW, Dougherty DM, James LM, Richard DM, Dawes MA, Acheson A, Hill-Kapturczak N (2011) Intolerance to delayed reward in girls with multiple suicide attempts. Suicide Life-Threatening Behavior 41(3):277–286. https://doi.org/10.1111/j.1943-278X.2011.00027.x
Wells GA, Shea B, O’Connel D, Peterson J, Welsch V, Losos M, Tugwell P (2017) The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses. Accessed 1 Nov 2017
Criaud M, Boulinguez P (2013) Have we been asking the right questions when assessing response inhibition in go/no-go tasks with fMRI? A meta-analysis and critical review. Neurosci Biobehav Rev 37(1):11–23. https://doi.org/10.1016/j.neubiorev.2012.11.003
Pan LA, Batezati-Alves SC, Almeida JR, Segreti A, Akkal D, Hassel S, Lakdawala S, Brent DA, Phillips ML (2011) Dissociable patterns of neural activity during response inhibition in depressed adolescents with and without suicidal behavior. J Am Acad Child Adolesc Psychiatry 50(6):602–611.e603. https://doi.org/10.1016/j.jaac.2011.03.018
Stewart JG, Kim JC, Esposito EC, Gold J, Nock MK, Auerbach RP (2015) Predicting suicide attempts in depressed adolescents: clarifying the role of disinhibition and childhood sexual abuse. J Affect Disord 187:27–34. https://doi.org/10.1016/j.jad.2015.08.034
Horesh N (2001) Self-report vs. computerized measures of impulsivity as a correlate of suicidal behavior. Crisis 22(1):27–31. https://doi.org/10.1027/0227-5910.22.1.27
Stewart JG, Glenn CR, Esposito EC, Cha CB, Nock MK, Auerbach RP (2017) Cognitive control deficits differentiate adolescent suicide ideators from attempters. J Clin Psychiatry. https://doi.org/10.4088/JCP.16m10647
Nock MK, Banaji MR (2007) Prediction of suicide ideation and attempts among adolescents using a brief performance-based test. J Consult Clin Psychol 75(5):707–715. https://doi.org/10.1037/0022-006X.75.5.707
Dickstein DP, Puzia ME, Cushman GK, Weissman AB, Wegbreit E, Kim KL, Nock MK, Spirito A (2015) Self-injurious implicit attitudes among adolescent suicide attempters versus those engaged in nonsuicidal self-injury. J Child Psychol Psychiatry 56(10):1127–1136. https://doi.org/10.1111/jcpp.12385
Millner AJ, Augenstein TM, Visser KH, Gallagher K, Vergara GA, D'Angelo EJ, Nock MK (2018) Implicit cognitions as a behavioral marker of suicide attempts in adolescents. Arch Suicide Res 2018:1–17. https://doi.org/10.1080/13811118.2017.1421488
Nock MK, Park JM, Finn CT, Deliberto TL, Dour HJ, Banaji MR (2010) Measuring the suicidal mind: implicit cognition predicts suicidal behavior. Psychol Sci 21(4):511–517. https://doi.org/10.1177/0956797610364762
Bridge JA, McBee-Strayer SM, Cannon EA, Sheftall AH, Reynolds B, Campo JV, Pajer KA, Barbe RP, Brent DA (2012) Impaired decision making in adolescent suicide attempters. J Am Acad Child Adolesc Psychiatry 51(4):394–403. https://doi.org/10.1016/j.jaac.2012.01.002
Oldershaw A, Grima E, Jollant F, Richards C, Simic M, Taylor L, Schmidt U (2009) Decision making and problem solving in adolescents who deliberately self-harm. Psychol Med 39(1):95–104. https://doi.org/10.1017/S0033291708003693
Pan LA, Segreti A, Almeida J, Jollant F, Lawrence N, Brent D, Phillips M (2013) Preserved hippocampal function during learning in the context of risk in adolescent suicide attempt. Psychiatry Res 211(2):112–118. https://doi.org/10.1016/j.pscychresns.2012.07.008
Ackerman JP, McBee-Strayer SM, Mendoza K, Stevens J, Sheftall AH, Campo JV, Bridge JA (2015) Risk-sensitive decision-making deficit in adolescent suicide attempters. J Child Adolesc Psychopharmacol 25(2):109–113. https://doi.org/10.1089/cap.2014.0041
Hadlaczky G, Hokby S, Mkrtchian A, Wasserman D, Balazs J, Machin N, Sarchiapone M, Sisask M, Carli V (2018) Decision-making in suicidal behavior: the protective role of loss aversion. Front Psychiatry 9:116. https://doi.org/10.3389/fpsyt.2018.00116
Bridge JA, Reynolds B, McBee-Strayer SM, Sheftall AH, Ackerman J, Stevens J, Mendoza K, Campo JV, Brent DA (2015) Impulsive aggression, delay discounting, and adolescent suicide attempts: effects of current psychotropic medication use and family history of suicidal behavior. J Child Adolesc Psychopharmacol 25(2):114–123. https://doi.org/10.1089/cap.2014.0042
Auerbach RP, Millner AJ, Stewart JG, Esposito EC (2015) Identifying differences between depressed adolescent suicide ideators and attempters. J Affect Disord 186:127–133. https://doi.org/10.1016/j.jad.2015.06.031
Cha CB, Najmi S, Park JM, Finn CT, Nock MK (2010) Attentional bias toward suicide-related stimuli predicts suicidal behavior. J Abnorm Psychol 119(3):616–622. https://doi.org/10.1037/a0019710
Steinberg L, Morris AS (2001) Adolescent development. Annu Rev Psychol 52:83–110
Paus T, Keshavan MS, Giedd JN (2008) Why do many psychiatric disorders emerge during adolescence? Nat Rev Neurosci 9:947–957
Shaw P, Gogtay N, Rapoport J (2010) Childhood psychiatric disorders as anomalies in neurodevelopmental trajectories. Hum Brain Mapp 31(6):917–925. https://doi.org/10.1002/hbm.21028
Fuster JM (2002) Frontal lobe and cognitive development. J Neurocytol 31(3–5):373–385
Giedd JN, Raznahan A, Alexander-Bloch A, Schmitt E, Gogtay N, Rapoport JL (2015) Child psychiatry branch of the National Institute of Mental Health longitudinal structural magnetic resonance imaging study of human brain development. Neuropsychopharmacology 40(1):43–49. https://doi.org/10.1038/npp.2014.236
Giedd JN, Blumenthal J, Jeffries NO, Castellanos FX, Liu H, Zijdenbos AP, Paus T, Evans AC, Rapoport J (1999) Brain development during childhood and adolescence—a longitudinal MRI study. Nat Neurosci 2(10):861–863
Gogtay N, Giedd JN, Lusk L, Hayashi KM, Greenstein D, Vaituzis AC, Nugent TF 3rd, Herman DH, Clasen LS, Toga AW, Rapoport JL, Thompson PM (2004) Dynamic mapping of human cortical development during childhood through early adulthood. Proc Natl Acad Sci USA 101(21):8174–8179. https://doi.org/10.1073/pnas.0402680101
Sowell ER, Peterson BS, Thompson PM, Welcome SE, Henkenius AL, Toga AW (2003) Mapping cortical change across the human life span. Nat Neurosci 6(3):309–315. https://doi.org/10.1038/nn1008
Huttenlocher P, Dabholkar AS (1997) Regional differences in synaptogenesisin human cerebral cortex. J Comp Neurol 387:167–178
Whitaker KJ, Vertes PE, Romero-Garcia R, Vasa F, Moutoussis M, Prabhu G, Weiskopf N, Callaghan MF, Wagstyl K, Rittman T, Tait R, Ooi C, Suckling J, Inkster B, Fonagy P, Dolan RJ, Jones PB, Goodyer IM (2016) Adolescence is associated with genomically patterned consolidation of the hubs of the human brain connectome. Proc Natl Acad Sci USA 113(32):9105–9110. https://doi.org/10.1073/pnas.1601745113
Chambers RC, Taylor JR, Potenza MN (2003) Developmental neurocircuitry of motivation in adolescence—a critical period of addiction vulnerability. Am J Psychiatry 160(6):1041–1052
Cohen JR, Asarnow RF, Sabb FW, Bilder RM, Bookheimer SY, Knowlton BJ, Poldrack RA (2010) A unique adolescent response to reward prediction errors. Nat Neurosci 13(6):669–671. https://doi.org/10.1038/nn.2558
Eshel N, Nelson EE, Blair RJ, Pine DS, Ernst M (2007) Neural substrates of choice selection in adults and adolescents: development of the ventrolateral prefrontal and anterior cingulate cortices. Neuropsychologia 45(6):1270–1279. https://doi.org/10.1016/j.neuropsychologia.2006.10.004
Galvan A (2010) Adolescent development of the reward system. Front Hum Neurosci 4:6. https://doi.org/10.3389/neuro.09.006.2010
Steinberg L, Albert D, Cauffman E, Banich M, Graham S, Woolard J (2008) Age differences in sensation seeking and impulsivity as indexed by behavior and self-report: evidence for a dual systems model. Dev Psychol 44(6):1764–1778. https://doi.org/10.1037/a0012955
Chein J, Albert D, O'Brien L, Uckert K, Steinberg L (2011) Peers increase adolescent risk taking by enhancing activity in the brain's reward circuitry. Dev Sci 14(2):F1–10. https://doi.org/10.1111/j.1467-7687.2010.01035.x
Shulman EP, Smith AR, Silva K, Icenogle G, Duell N, Chein J, Steinberg L (2016) The dual systems model: review, reappraisal, and reaffirmation. Dev Cogn Neurosci 17:103–117. https://doi.org/10.1016/j.dcn.2015.12.010
Casey B, Jones RM, Hare TA (2008) The adolescent brain. Ann N Y Acad Sci 1124:3. https://doi.org/10.1196/annals.1440.010
Ho TC, Dennis EL, Thompson PM, Gotlib IH (2018) Network-based approaches to examining stress in the adolescent brain. Neurobiol Stress 8:147–157. https://doi.org/10.1016/j.ynstr.2018.05.002
Castellvi P, Miranda-Mendizabal A, Pares-Badell O, Almenara J, Alonso I, Blasco MJ, Cebria A, Gabilondo A, Gili M, Lagares C, Piqueras JA, Roca M, Rodriguez-Marin J, Rodriguez-Jimenez T, Soto-Sanz V, Alonso J (2017) Exposure to violence, a risk for suicide in youths and young adults A meta-analysis of longitudinal studies. Acta Psychiatr Scand 135(3):195–211. https://doi.org/10.1111/acps.12679
Seguin M, Lesage A, Turecki G, Bouchard M, Chawky N, Tremblay N, Daigle F, Guy A (2007) Life trajectories and burden of adversity: mapping the developmental profiles of suicide mortality. Psychol Med 37(11):1575–1583. https://doi.org/10.1017/S0033291707000955
Seguin M, Beauchamp G, Robert M, DiMambro M, Turecki G (2014) Developmental model of suicide trajectories. Br J Psychiatry 205(2):120–126. https://doi.org/10.1192/bjp.bp.113.139949
Aas M, Dazzan P, Fisher HL, Morgan C, Morgan K, Reichenberg A, Zanelli J, Fearon P, Jones PB, Murray RM, Pariante CM (2011) Childhood trauma and cognitive function in first-episode affective and non-affective psychosis. Schizophr Res 129(1):12–19. https://doi.org/10.1016/j.schres.2011.03.017
Ivy AS, Rex CS, Chen Y, Dube C, Maras PM, Grigoriadis DE, Gall CM, Lynch G, Baram TZ (2010) Hippocampal dysfunction and cognitive impairments provoked by chronic early-life stress involve excessive activation of CRH receptors. J Neurosci 30(39):13005–13015. https://doi.org/10.1523/JNEUROSCI.1784-10.2010
Kaplan GA, Turrell G, Lynch JW, Everson SA, Helkala E, Salonen JT (2001) Childhood socioeconomic position and cognitive function in adulthood. Int J Epidemiol 30:256–263
Nelson CA, Zeanah CH, Fox NA, Marshall PJ, Smyke AT, Guthrie D (2007) Cognitive recovery in socially deprived young children—the bucharest early intervention project. Science 318(5858):1937–1940
McCrory E, De Brito SA, Viding E (2010) Research review: the neurobiology and genetics of maltreatment and adversity. J Child Psychol Psychiatry 51(10):1079–1095. https://doi.org/10.1111/j.1469-7610.2010.02271.x
Turecki G, Ernst C, Jollant F, Labonte B, Mechawar N (2012) The neurodevelopmental origins of suicidal behavior. Trends Neurosci 35(1):14–23. https://doi.org/10.1016/j.tins.2011.11.008
Eiland L, Romeo RD (2013) Stress and the developing adolescent brain. Neuroscience 249:162–171. https://doi.org/10.1016/j.neuroscience.2012.10.048
Williams JM, Barnhofer T, Crane C, Beck AT (2005) Problem solving deteriorates following mood challenge in formerly depressed patients with a history of suicidal ideation. J Abnorm Psychol 114(3):421–431. https://doi.org/10.1037/0021-843X.114.3.421
van den Bos R, Harteveld M, Stoop H (2009) Stress and decision-making in humans: performance is related to cortisol reactivity, albeit differently in men and women. Psychoneuroendocrinology 34(10):1449–1458. https://doi.org/10.1016/j.psyneuen.2009.04.016
Tomoda A, Suzuki H, Rabi K, Sheu YS, Polcari A, Teicher MH (2009) Reduced prefrontal cortical gray matter volume in young adults exposed to harsh corporal punishment. Neuroimage 47(Suppl 2):T66–71. https://doi.org/10.1016/j.neuroimage.2009.03.005
Kitayama N, Quinn S, Bremner JD (2006) Smaller volume of anterior cingulate cortex in abuse-related posttraumatic stress disorder. J Affect Disord 90(2–3):171–174. https://doi.org/10.1016/j.jad.2005.11.006
Weniger G, Lange C, Sachsse U, Irle E (2008) Amygdala and hippocampal volumes and cognition in adult survivors of childhood abuse with dissociative disorders. Acta Psychiatr Scand 118(4):281–290. https://doi.org/10.1111/j.1600-0447.2008.01246.x
Tomoda A, Sheu YS, Rabi K, Suzuki H, Navalta CP, Polcari A, Teicher MH (2011) Exposure to parental verbal abuse is associated with increased gray matter volume in superior temporal gyrus. Neuroimage 54(Suppl 1):S280–286. https://doi.org/10.1016/j.neuroimage.2010.05.027
Teicher MH, Dumont NL, Ito Y, Vaituzis C, Giedd JN, Andersen SL (2004) Childhood neglect is associated with reduced corpus callosum area. Biol Psychiatry 56(2):80–85. https://doi.org/10.1016/j.biopsych.2004.03.016
Grover KE, Green KL, Pettit JW, Monteith LL, Garza MJ, Venta A (2009) Problem solving moderates the effects of life event stress and chronic stress on suicidal behaviors in adolescence. J Clin Psychol 65(12):1281–1290. https://doi.org/10.1002/jclp.20632
Yang B, Clum GA (2000) Childhood stress leads to later suicidality via its effect on cognitive functioning. Suicide Life Threatening Behavior 30(3):183–198
Geoffroy MC, Boivin M, Arseneault L, Renaud J, Perret LC, Turecki G, Michel G, Salla J, Vitaro F, Brendgen M, Tremblay RE, Cote SM (2018) Childhood trajectories of peer victimization and prediction of mental health outcomes in midadolescence: a longitudinal population-based study. Can Med Assoc J 190(2):E37E43. https://doi.org/10.1503/cmaj.170219
Guillaume S, Perroud N, Jollant F, Jaussent I, Olie E, Malafosse A, Courtet P (2013) HPA axis genes may modulate the effect of childhood adversities on decision-making in suicide attempters. J Psychiatr Res 47(2):259–265. https://doi.org/10.1016/j.jpsychires.2012.10.014
Lincoln SH, Pisoni A, Bondy E, Kumar P, Singleton P, Hajcak G, Pizzagalli DA, Auerbach RP (2019) Altered reward processing following an acute social stressor in adolescents. PLoS ONE 14(1):e0209361. https://doi.org/10.1371/journal.pone.0209361
Oldershaw A, Simic M, Grima E, Jollant F, Richards C, Taylor L, Schmidt U (2012) The effect of cognitive behavior therapy on decision making in adolescents who self-harm: a pilot study. Suicide Life Threatening Behavior 42(3):255–265. https://doi.org/10.1111/j.1943-278X.2012.0087.x
Ougrin D, Tranah T, Stahl D, Moran P, Asarnow JR (2015) Therapeutic interventions for suicide attempts and self-harm in adolescents: systematic review and meta-analysis. J Am Acad Child Adolesc Psychiatry 54(2):97–107. https://doi.org/10.1016/j.jaac.2014.10.009
Acknowledgements
We would like to acknowledge the contribution of Dr. Valentin Mbekou, who, unfortunately, past away during the elaboration of the manuscript. Dr. Mbekou collaborated on the design of the review and had approved an earlier version. The authors also appreciated the editing work performed by Daysi Zentner on a previous version.
Funding
This work was supported by the Manulife Teen Mental Health Research Fund, without any involvement in the study or in the writing process. JR holds a grant from Manulife Teen Mental Health Research Fund. AG holds a training award from the Fonds de Recherche du Québec en Santé (FQR-S/MSSS training Program for specialty medicine residents with interest in pursuing a research career—Phase 1). MCG also holds a salary award from Fonds de Recherche du Québec en Santé (FRQ-S) (Junior 1). LP holds a doctoral award from FRQ-S. EL, VM, FJ have no financial disclosure.
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Gifuni, A.J., Perret, L.C., Lacourse, E. et al. Decision-making and cognitive control in adolescent suicidal behaviors: a qualitative systematic review of the literature. Eur Child Adolesc Psychiatry 30, 1839–1855 (2021). https://doi.org/10.1007/s00787-020-01550-3
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DOI: https://doi.org/10.1007/s00787-020-01550-3