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Diagnostic efficiency of the CBCL thought problems and DSM-oriented psychotic symptoms scales for pediatric psychotic symptoms

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Abstract

We compared the diagnostic efficiency of the Child Behavior Checklist (CBCL) Thought Problems subscale and the rationally derived DSM-oriented psychotic symptoms scale (DOPSS) to identify clinically concerning psychosis in a multi-site sample of youths seeking outpatient mental health services (N = 694). We operationally defined clinically concerning psychosis as the presence of clinically significant hallucinations or delusions, assessed by the Schedule for Affective Disorders and Schizophrenia psychosis items. Both the Thought Problems and DOPSS scores showed significant areas under the curve (AUCs = 0.65 and 0.70, respectively), but the briefer DOPSS showed statistically significantly better diagnostic efficiency for any clinically concerning psychosis, but the difference was small enough that it would not be clinically meaningful. The optimal psychosis screening cut-off score (maximizing sensitivity and specificity) was 68.5+ [corresponding diagnostic likelihood ratio (DiLR) = 1.59] for the Thought Problems subscale and 1.67+ (DiLR = 1.97) for the DOPSS. Both the CBCL Thought Problems and DOPSS are clinically useful for identifying psychotic symptoms in children, and although the DOPSS showed statistically better discriminating power, the difference was small so we would not necessarily recommend the DOPSS over standard scoring.

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Acknowledgements

The main outcome study was funded by NIH R01MH066647 from the National Institute of Mental Health (PI: Eric A. Youngstrom). Dr. Eric Youngstrom served as a statistical expert for the study.

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Correspondence to Eric A. Youngstrom.

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Conflict of interest

Dr. Findling receives or has received research support, acted as a consultant and/or served on a speaker’s bureau for Actavis, Akili, Alcobra, American Academy of Child & Adolescent Psychiatry, American Psychiatric Press, Bracket, CogCubed, Cognition Group, Coronado Biosciences, Elsevier, Epharma Solutions, Forest, Genentech, GlaxoSmithKline, Guilford Press, Ironshore, Johns Hopkins University Press, KemPharm, Lundbeck, Medgenics, Merck, NIH, Neurim, Novartis, Otsuka, PCORI, Pfizer, Physicians Postgraduate Press, Purdue, Rhodes Pharmaceuticals, Roche, Sage, Shire, Sunovion, Supernus Pharmaceuticals, Syneurx, Takeda, Teva, Tris, Validus, and WebMD. Dr. E. Youngstrom has consulted with Pearson, Lundbeck, Janssen, Western Psychological Services, and Joe Startup Technologies about psychological assessment. Ms. Salcedo, Dr. Rizvi, Ms. Freeman, and Dr. J. Youngstrom have no conflicts to disclose.

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Salcedo, S., Rizvi, S.H., Freeman, L.K. et al. Diagnostic efficiency of the CBCL thought problems and DSM-oriented psychotic symptoms scales for pediatric psychotic symptoms. Eur Child Adolesc Psychiatry 27, 1491–1498 (2018). https://doi.org/10.1007/s00787-018-1140-1

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