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Quality of life in children with OCD before and after treatment

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Abstract

Quality of life (QoL) is a well-established outcome measure. In contrast to adult obsessive–compulsive disorder (OCD), little is known about the effects of treatment on QoL in children with OCD. This study aimed to assess QoL after cognitive behavioural therapy (CBT) in children and adolescents with OCD compared with the general population and to explore factors associated with potential changes in QoL after treatment. QoL was assessed in 135 children and adolescents (ages 7–17; mean 13 [SD 2.7] years; 48.1 % female) before and after 14 CBT sessions, using self-report and a caregivers proxy report of the Questionnaire for Measuring Health-related Quality of Life in Children and Adolescents (KINDL-R). QoL was compared with an age- and gender-matched sample from the general population. Before treatment, QoL was markedly lower in children with OCD compared with the general population. QoL improved significantly in CBT responders (mean score change 7.4), to the same range as QoL in the general population. Non-responders reported no QoL changes after treatment, except for one patient. Comorbidity, family accommodation and psychosocial functioning were not associated with changes in QoL after treatment. To our knowledge, this is the first study of the changes in QoL after treatment of paediatric OCD. The assessment of QoL beyond symptoms and function in children with OCD has been shown to be reliable and informative. The results of this study support the application of QoL assessment as an additional measure of treatment outcome in children and adolescents with OCD.

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Acknowledgments

This study was funded with support by the Norwegian Research Council and St. Olav’s Hospital, Department of Child and Adolescent Psychiatry, Trondheim. We wish to thank all patients, parents, and the participating clinics for their contribution to the study.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethics

The study was approved by the Regional Committees for Medical and Health Research Ethics in Denmark, Norway and Sweden. All parents gave written informed consent and the permission for their children to participate before inclusion in the study.

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Authors and Affiliations

  1. Department of Child and Adolescent Psychiatry, St.Olavs University Hospital, Post box 6810, Elgeseter, 7433, Trondheim, Norway

    Bernhard Weidle & Thomas Jozefiak

  2. Faculty of Medicine, Regional Centre for Child and Youth Mental Health and Child Welfare, Norwegian University of Science and Technology, Trondheim, Norway

    Bernhard Weidle, Stian Lydersen & Thomas Jozefiak

  3. Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Gullhaugveien 1-3, 0484, Oslo, Norway

    Tord Ivarsson

  4. Department of Child and Adolescent Psychiatry, Göteborg University, Kungsgatan 12, SE-411 19, Göteborg, Sweden

    Tord Ivarsson

  5. Psychiatric Hospital for Children and Adolescents, University Hospital in Aarhus, Aarhus, Denmark

    Per Hove Thomsen

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  1. Bernhard Weidle
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Correspondence to Bernhard Weidle.

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Weidle, B., Ivarsson, T., Thomsen, P.H. et al. Quality of life in children with OCD before and after treatment. Eur Child Adolesc Psychiatry 24, 1061–1074 (2015). https://doi.org/10.1007/s00787-014-0659-z

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