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Subthreshold depression in adolescence: a systematic review

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Abstract

In adolescence, the number of depressive symptoms is rising notably. Individuals may have relevant depressive symptoms without meeting the full criteria of a major depressive episode (MDE), a condition referred to as subthreshold depression (sD). This article presents a review on adolescent sD examining the prevalence, the quality of life (QoL), the risk of developing MDE, and preventive programs available for adolescents living with sD. A systematic literature search from the year of the introduction of Diagnostic and Statistic Manual for Mental Disorders Fourth Edition (DSM-IV) until 2012 (18 years) was conducted with a special focus on adolescent sD. Data from 27 studies were included into this review. The results show high prevalence of sD among adolescents, with a negative impact on QoL, and provide evidence that sD is a significant risk indicator of later MDE; therefore, individuals with sD represent good targets for preventive interventions. Our review highlights the fact that sD is a significant health problem among adolescents indeed, and adolescents with sD could be a subgroup of youth, who need further help to reduce their clinically significant depressive symptoms for the successful prevention of a later MDE.

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Acknowledgments

The authors wish to thank Agnes Kereszteny for her diligent help with literature search.

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On behalf of all authors, the corresponding author states that there is no conflict of interest.

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Correspondence to Eszter A. Bertha.

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Bertha, E.A., Balázs, J. Subthreshold depression in adolescence: a systematic review. Eur Child Adolesc Psychiatry 22, 589–603 (2013). https://doi.org/10.1007/s00787-013-0411-0

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