Abstract
Conduct disorder (CD) is a frequently occurring psychiatric disorder characterized by a persistent pattern of aggressive and non-aggressive rule breaking antisocial behaviours that lead to considerable burden for the patients themselves, their family and society. This review paper updates diagnostic and therapeutic approaches to CD in the light of the forthcoming DSM-5 definition. The diagnostic criteria for CD will remain unchanged in DSM-5, but the introduction of a specifier of CD with a callous-unemotional (CU) presentation is new. Linked to this, we discuss the pros and cons of various other ways to subtype aggression/CD symptoms. Existing guidelines for CD are, with few exceptions, already of a relatively older date and emphasize that clinical assessment should be systematic and comprehensive and based on a multi-informant approach. Non-medical psychosocial interventions are recommended as the first option for the treatment of CD. There is a role for medication in the treatment of comorbid syndromes and/or in case of insufficient response to psychosocial interventions and severe and dangerous aggressive and violent behaviours.
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References
AACAP (1992) Practice parameters for the assessment and treatment of conduct disorders. American Academy of Child and Adolescent Psychiatry. J Am Acad Child Adolesc Psychiatry 31(2):IV–VII
American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Association, Washington, DC
Biederman J, Newcorn J, Sprich S (1991) Comorbidity of attention deficit hyperactivity disorder with conduct, depressive, anxiety, and other disorders. Am J Psychiatry 148:564–577
Borduin CM, Mann BJ, Cone LT, Henggeler SW, Fucci BR, Blaske DM, Williams RA (1995) Multisystemic treatment of serious juvenile offenders: long-term prevention of criminality and violence. J Consult Clin Psychol 63(4):569–578
Campbell M, Small AM, Green WH, Jennings SJ, Perry R, Bennett WG, Anderson L (1984) Behavioral efficacy of haloperidol and lithium carbonate. A comparison in hospitalized aggressive children with conduct disorder. Arch Gen Psychiatry 41(7):650–656
Connor DF, Glatt SJ, Lopez ID, Jackson D, Melloni RH, Jr (2002) Psychopharmacology and aggression. I: A meta-analysis of stimulant effects on overt/covert aggression-related behaviors in ADHD. J Am Acad Child Adolesc Psychiatry 41(3):253–261
Connor DF, Carlson GA, Chang KD, Daniolos PT, Ferziger R, Findling RL, Hutchinson JG, Malone RP, Halperin JM, Plattner B, Post RM, Reynolds DL, Rogers KM, Saxena K, Steiner H (2006) Juvenile maladaptive aggression: a review of prevention, treatment, and service configuration and a proposed research agenda. J Clin Psychiatry 67(5):808–820
Dodge KA, Coie JD (1987) Social-information-processing factors in reactive and proactive aggression in children’s peer groups. J Pers Soc Psychol 53(6):1146–1158
Eddy JM, Chamberlain P (2000) Family management and deviant peer association as mediators of the impact of treatment condition on youth antisocial behavior. J Consul Clin Psychol 68(5):857–863
Fairchild G, Passamonti L, Hurford G, Hagan CC, von dem Hagen EA, van Goozen SH, Goodyer IM, Calder AJ (2011) Brain structure abnormalities in early-onset and adolescent-onset conduct disorder. Am J Psychiatry 168(6):624–633
Frick PJ, Dickens C (2006) Current perspectives on conduct disorder. Curr Psychiatry Rep 8(1):59–72
Frick PJ, White SF (2008) Research review: the importance of callous-unemotional traits for developmental models of aggressive and antisocial behavior. J Child Psychol Psychiatry 49(4):359–375
Frick PJ (2006) Developmental pathways to conduct disorder. Child Adolesc Psychiatr Clinics North Am 15(2):311–331
Hawes DJ, Dadds MR (2005) The treatment of conduct problems in children with callous-unemotional traits. J Consult Clin Psychol 73(4):737–741
Henggeler SW, Sheidow AJ (2012) Empirically supported family-based treatments for conduct disorder and delinquency in adolescents. J Marital Fam Ther 38(1):30–58
Herpers PC, Rommelse NN, Bons DM, Buitelaar JK, Scheepers FE (2012) Callous-unemotional traits as a cross-disorders construct. Soc Psychiatry Psychiatr Epidemiol 9:1–20
Jaselskis CA, Cook EHJ, Fletcher KEL, Leventhal BL (1992) Clonidine treatment of hyperactive and impulsive children with autistic disorder. J Clin Psychopharmacol 12(5):322–327
Kazdin AE (1997) Practitioner review: psychosocial treatments for conduct disorder in children. J Child Psychol Psychiatry 38(2):161–178
Kazdin AE, Whitley MK (2006) Comorbidity, case complexity, and effects of evidence-based treatment for children referred for disruptive behavior. J Consult Clin Psychol 74(3):455–467
Kempes M, Matthys W, Maassen G, van Goozen S, van Engeland H (2006) A parent questionnaire for distinguishing between reactive and proactive aggression in children. Eur Child Adolesc Psychiatry 15(1):38–45
Kutcher S, Aman M, Brooks SJ, Buitelaar J, van Daalen E, Fegert J, Findling RL, Fisman S, Greenhill LL, Huss M, Kusumakar V, Pine D, Taylor E, Tyano S (2004) International consensus statement on attention-deficit/hyperactivity disorder (ADHD) and disruptive behaviour disorders (DBDs): clinical implications and treatment practice suggestions. Eur Neuropsychopharmacol 14(1):11–28
Lahey BB, Loeber R, Hart EL, Frick PJ, Applegate B, Zhang Q, Green SM, Russo MF (1995) Four-year longitudinal study of conduct disorder in boys: patterns and predictors of persistence. J Abnorm Child Psychols 104(1):83–93
Lahey BB, Waldman ID (2012) Annual research review: phenotypic and causal structure of conduct disorder in the broader context of prevalent forms of psychopathology. J Child Psychol Psychiatry 53(5):536–557
Lettinga JR, Drent C, Hoekstra PJ, Buitelaar JK, Glennon JC (2011) Clinical pharmacology of conduct disorder: a critical review. Child Adolesc Psychiatr News Letter 16(6):1–10. doi:10.1521/capn.2011.16.6.1
Malone RP, Delaney MA, Luebbert JF, Cater J, Campbell M (2000) A double-blind placebo-controlled study of lithium in hospitalized aggressive children and adolescents with conduct disorder. Arch Gen Psychiatry 57(7):649–654
Mannuzza S, Klein RG, Bessler A, Malloy P, LaPadula M (1998) Adult psychiatric status of hyperactive boys grown up. Am J Psychiatry 155(4):493–498
Moffitt TE (1993) Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. Psychol Rev 100:674–701
Pappadopulos E, Woolston S, Chait A, Perkins M, Connor DF, Jensen PS (2006) Pharmacotherapy of aggression in children and adolescents: efficacy and effect size. J Can Acad Child Adolesc Psychiatry 15(1):27–39
Pardini DA, Lochman JE, Frick PJ (2003) Callous/unemotional traits and social-cognitive processes in adjudicated youths. J Am Acad Child Adolesc Psychiatry 42(3):364–371
Passamonti L, Fairchild G, Goodyer IM, Hurford G, Hagan C, Rowe JB, Calder AJ (2010) Neural abnormalities in early-onset and adolescence-onset conduct disorder. Arch Gen Psychiatry 67(7):729–738. doi:10.1001/archgenpsychiatry.2010.75
Raine A (2011) An amygdala structural abnormality common to two subtypes of conduct disorder: a neurodevelopmental conundrum. Am J Psychiatry 168(6):569–571
Robins LN (1991) Conduct disorder. J Child Psychol Psychiatry 32(1):193–212
Romeo R, Knapp M, Scott S (2006) Economic cost of severe antisocial behaviour in children—and who pays it. Br J Psychiatry 188:547–553
Rowe R, Maughan B, Moran P, Ford T, Briskman J, Goodman R (2010) The role of callous and unemotional traits in the diagnosis of conduct disorder. J Child Psychol Psychiatry 51(6):688–695
Scahill L, Chappell PB, Kim YS, Schultz RT, Katsovich L, Shepherd E, Arnsten AF, Cohen DJ, Leckman JF (2001) A placebo-controlled study of guanfacine in the treatment of children with tic disorders and attention deficit hyperactivity disorder. Am J Psychiatry 158(7):1067–1074
Scheepers FE, Buitelaar JK, Matthys W (2011) Conduct disorder and the specifier callous and unemotional traits in the DSM-5. Eur Child Adolesc Psychiatry 20(2):89–93
Spain SE, Douglas KS, Poythress NG, Epstein M (2004) The relationship between psychopathic features, violence and treatment outcome: the comparison of three youth measures of psychopathic features. Behav Sci Law 22(1):85–102. doi:10.1002/bsl.576
Tremblay RE (2010) Developmental origins of disruptive behaviour problems: the ‘original sin’ hypothesis, epigenetics and their consequences for prevention. J Child Psychol Psychiatry 51(4):341–367
Viding E, Blair RJ, Moffitt TE, Plomin R (2005) Evidence for substantial genetic risk for psychopathy in 7-year-olds. J Child Psychol Psychiatry 46(6):592–597
Viding E, Jones AP, Frick PJ, Moffitt TE, Plomin R (2008) Heritability of antisocial behaviour at 9: do callous-unemotional traits matter? Developmental Sci 11(1):17–22
Waddell C, Lipman E, Offord D (1999) Conduct disorder: practice parameters for assessment, treatment, and prevention. Can J Psychiatry 44(2):35S–40S
Walters GD (2011) The latent structure of life-course-persistent antisocial behavior: is Moffitt’s developmental taxonomy a true taxonomy? J Consult Clin Psychol 79(1):96–105
Werry JS, Aman MG, Lampen E (1976) Haloperidol and methylphenidate in hyperactive children. Acta Paedopsychiatrica 42(1):26–40
Conflict of interest
Jan K Buitelaar has in the past 3 years been a consultant to/member of the advisory board of and/or a speaker for Janssen Cilag BV, Eli Lilly, Bristol-Myer Squibb, Shering Plough, UCB, Shire, and Novartis and Servier. He is not an employee of any of these companies and is not a stock shareholder of any of these companies. He has no other financial or material support, including expert testimony, patents and royalties. This article is part of the supplement “The Future of Child and Adolescent Psychiatry and Psychology: The Impact of DSM 5 and of Guidelines for Assessment and Treatment”. This supplement was not sponsored by outside commercial interests.
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Buitelaar, J.K., Smeets, K.C., Herpers, P. et al. Conduct disorders. Eur Child Adolesc Psychiatry 22 (Suppl 1), 49–54 (2013). https://doi.org/10.1007/s00787-012-0361-y
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DOI: https://doi.org/10.1007/s00787-012-0361-y