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Epidemiology of psychiatric disorders in very young children in a Romanian pediatric setting

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Abstract

A growing literature demonstrates that early clinical intervention can reduce risks of adverse psychosocial outcomes. A first step necessary for developing early intervention services is to know the prevalence of clinical disorders, especially in systems that are rebuilding, such as Romania, where the mental health system was dismantled under Ceausescu. No epidemiologic studies have examined prevalence of psychiatric disorders in young children in Romania. The objective of this study was to determine the prevalence of psychiatric disorders in Romanian children 18–60 months in pediatric settings. Parents of 1,003 children 18–60 months in pediatric waiting rooms of two pediatric hospitals completed background information, the Child Behavior Checklist (CBCL). A subgroup over-sampled for high mental health problems were invited to participate in the Preschool Age Psychiatric Assessment. Rates of mental health problems were similar to the US norms on the CBCL. The weighted prevalence of psychiatric disorders in these children was 8.8%, with 5.4% with emotional disorders and 1.4% with behavioral disorders. Comorbidity occurred in nearly one-fourth of the children with a psychiatric disorder and children who met diagnostic criteria had more functional impairment than those without. Of children who met criteria for a psychiatric disorder, 10% of parents were concerned about their child’s emotional or behavioral health. This study provides prevalence rates of psychiatric disorders in young Romanian children, clinical characteristic of the children and families that can guide developing system of care. Cultural differences in parental report of emotional and behavioral problems warrant further examination.

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References

  1. AACAP Task Force on Research Diagnostic Criteria: Infancy Preschool Age (2003) Research diagnostic criteria for infants and preschool children: the process and empirical support. J Am Acad Child Adolesc Psychiatry 42:1504–1512

    Article  Google Scholar 

  2. Achenbach T, Rescorla L (2000) Manual for the ASEBA Preschool form. University of Vermont, Burlington

    Google Scholar 

  3. Adler N, Mueller GO, Ayat M (1993) Psychiatry under tyranny: a report on the political abuse of Romanian psychiatry during the Ceausescu years. Current Psychology 12:3

    Article  PubMed  Google Scholar 

  4. Alonso J, Lepine J-P (2007) Overview of key data from the European Study of the Epidemiology of Mental Disorders (ESEMeD). J Clin Psychiatry 68S:3–9

    Google Scholar 

  5. Avan B, Richter LM, Ramchandani PG, Norris SA, Stein A (2010) Maternal postnatal depression and children’s growth and behaviour during the early years of life: exploring the interaction between physical and mental health. Arch Dis Child 95:690–695

    Article  PubMed  Google Scholar 

  6. Briggs-Gowan MJ, Carter AS, Bosson-Heenan J, Guyer AE, Horwitz SM (2006) Are infant-toddler social-emotional and behavioral problems transient? J Am Acad Child Adolesc Psychiatry 45:849–858

    Article  PubMed  Google Scholar 

  7. Briggs-Gowan MJ, Ford JD, Fraleigh L, McCarthy K, Carter AS (2010) Prevalence of exposure to potentially traumatic events in a healthy birth cohort of very young children in the northeastern United States. J Trauma Stress 23:725–733

    Article  PubMed  Google Scholar 

  8. Bywater T, Hutchings J, Daley D, Whitaker C, Yeo ST, Jones K, Eames C, Edwards RT (2009) Long-term effectiveness of a parenting intervention for children at risk of developing conduct disorder. Br J Psychiatry 195:318–324

    Article  PubMed  Google Scholar 

  9. Carter AS, Wagmiller R, Gray S, McCarthy KJ, Horwitz SM, Briggs-Gowan MJ (2010) Prevalence of DSM-IV disorder in a representative, healthy birth cohort at school entry: sociodemographic risks and social adaptation. J Am Acad Child Adolesc Psychiatry 48:676–698

    Google Scholar 

  10. Costello EJ, Farmer EM, Angold A, Burns BJ, Erkanli A (1997) Psychiatric disorders among American Indian and white youth in Appalachia: the Great Smoky Mountains Study. Am J Public Health 87:827–832

    Article  PubMed  CAS  Google Scholar 

  11. Costello EJ, Mustillo S, Erkanli A, Keeler G, Angold A (2003) Prevalence and development of psychiatric disorders in childhood and adolescence. Arch Gen Psychiatry 60:837–844

    Article  PubMed  Google Scholar 

  12. Domenech-Llaberia E, Vinas F, Pia E, Jane MC, Mitjavila M, Corbella T, Canals J (2009) Prevalence of major depression in preschool children. Eur Child Adolesc Psychiatry 18:597

    Article  PubMed  Google Scholar 

  13. Dong M, Giles WH, Felitti VJ, Dube SR, Williams JE, Chapman DP, Anda RF (2004) Insights into causal pathways for ischemic heart disease: adverse childhood experiences study. Circulation 110:1761–1766

    Article  PubMed  Google Scholar 

  14. Döpfner M, Breuer D, Wille N, Erhart M, Ravens-Sieberer U (2008) How often do children meet ICD-10/DSM-IV criteria of attention deficit-/hyperactivity disorder and hyperkinetic disorder? Parent-based prevalence rates in a national sample—results of the BELLA study. Eur Child Adolesc Psychiatry 17:59

    Article  PubMed  Google Scholar 

  15. Egger H, Erkanli A, Keeler G, Potts E, Walter B, Angold A (2006) Test–retest reliability of the Preschool Age Psychiatric Assessment (PAPA). J Am Acad Child Adolesc Psychiatry 45:538–549

    Article  PubMed  Google Scholar 

  16. Egger HL, Angold A (2006) Common emotional and behavioral disorders in preschool children: presentation, nosology, and epidemiology. J Child Psychol Psychiatry 47:313–337

    Article  PubMed  Google Scholar 

  17. Florescu S, Moldovan M, Mijhaescu-Pintia C, Ciutan M, Sorel GE (2007) The mental health study—Romania 2007: prevalence, severity, and treatment of 12 month DSM-IV disorders. In: Management in Health, vol 13. http://journal.managementinhealth.com/index.php/rms/article/view/30/103. Accessed 2 Jan 2011

  18. Flouri E, Tzavidis N, Kallis C (2010) Adverse life events, area socioeconomic disadvantage, and psychopathology and resilience in young children: the importance of risk factors’ accumulation and protective factors’ specificity. Eur Child Adolesc Psychiatry 19:535–546

    Article  PubMed  Google Scholar 

  19. Furniss T, Beyer T, Guggenmos J (2006) Prevalence of behavioural and emotional problems among six-years-old preschool children: baseline results of a prospective longitudinal study. Soc Psychiatry Psychiatr Epidemiol 41:394

    Article  PubMed  Google Scholar 

  20. Furniss T, Beyer T, Mueller J (2009) Impact of life events on child mental health before school entry at age six. Eur Child Adolesc Psychiatry 18:717–724

    Article  PubMed  Google Scholar 

  21. Gater R, Jordanova V, Maric N, Alikaj V, Bajs M, Cavic T, Dimitrov H, Iosub D, Mihai A, Szalontay AS, Helmchen H, Sartorius N (2005) Pathways to psychiatric care in Eastern Europe. Br J Psychiatry 186:529–535

    Article  PubMed  Google Scholar 

  22. Goodman A, Goodman R (2011) Population mean scores predict child mental disorder rates: validating SDQ prevalence estimators in Britain. J Child Psychol Psychiatry 52:100–108

    Article  PubMed  Google Scholar 

  23. Heckman JJ (2006) Skill formation and the economics of investing in disadvantaged children. Science 312:1900–1902

    Article  PubMed  CAS  Google Scholar 

  24. Hölling H, Kurth B-M, Rothenberger A, Becker A, Schlack R (2008) Assessing psychopathological problems of children and adolescents from 3 to 17 years in a nationwide representative sample: results of the German health interview and examination survey for children and adolescents (KiGGS). Eur Child Adolesc Psychiatry 17:34

    Article  PubMed  Google Scholar 

  25. Hood KK, Eyberg SM (2003) Outcomes of parent-child interaction therapy: mothers’ reports of maintenance three to six years after treatment. J Clin Child Adolesc Psychol 32:419–430

    Article  PubMed  Google Scholar 

  26. Huss M, Halling H, Kurth B-M, Schlack R (2008) How often are German children and adolescents diagnosed with ADHD? Prevalence based on the judgment of health care professionals: results of the German health and examination survey (KiGGS). Eur Child Adolesc Psychiatry 17:52

    Article  PubMed  Google Scholar 

  27. Ionescu C (2005) Depression in post-communist Romania. Lancet 365:345–346

    Google Scholar 

  28. Ivanovo MY, Achenbach TM, Rescorla LA, Harder VS, Ang RP, Bilenberg N, Bjarnadottir G, Capron C, De Pauw SSW, Dias P, Dobrean A, Doepfner M, Duyme M, Eapen V, Erol N, Esmaeili EM, Ezpeleta L, Frigerio A, Gonçalves MM, Gudmundsson HS, Jeng S-F, Jetishi P, Jusiene R, Kim Y-A, Kristensen S, Lecannelier F, Leung PWL, Liu J, Montirosso R, Oh KJ, Plueck J, Pomalima R, Shahini M, Silva JR, Simsek Z, Sourander A, Valverde J, Van Leeuwen KG, Woo BSC, Wu Y-T, Zubrick SR, Verhulst FC (2009) Preschool psychopathology reported by parents in 23 societies: testing the seven-syndrome model of the Child Behavior Checklist for ages 1.5–5. J Am Acad Child Adolesc Psychiatry 49:1215

  29. Keenan K, Shaw DS, Walsh B, Delliquadri E, Giovannelli J (1997) DSM-III-R disorders in preschool children from low-income families. J Am Acad Child Adolesc Psychiatry 36:620–627

    Article  PubMed  CAS  Google Scholar 

  30. Kim-Cohen J, Arseneault L, Newcombe R, Adams F, Bolton H, Cant L, Delgado K, Freeman J, Golaszewski A, Kelesidi K, Matthews C, Mountain N, Oxley D, Watson S, Werts H, Caspi A, Moffitt TE (2009) Five-year predictive validity of DSM-IV conduct disorder research diagnosis in 4 1/2–5-year-old children. Eur Child Adolesc Psychiatry 18:284–291

    Article  PubMed  Google Scholar 

  31. Lahey BB, Applegate B (2001) Validity of DSM-IV ADHD. J Am Acad Child Adolesc Psychiatry 40:502–503

    Article  PubMed  CAS  Google Scholar 

  32. Lavigne JV, Arend R, Rosenbaum D, Binns HJ, Christoffel KK, Gibbons RD (1998) Psychiatric disorders with onset in the preschool years: I. Stability of diagnoses. J Am Acad Child Adolesc Psychiatry 37:1246–1254

    Article  PubMed  CAS  Google Scholar 

  33. Lavigne JV, Gibbons RD, Christoffel KK, Arend R, Rosenbaum D, Binns H, Dawson N, Sobel H, Isaacs C (1996) Prevalence rates and correlates of psychiatric disorders among preschool children. J Am Acad Child Adolesc Psychiatry 35:205–214

    Article  Google Scholar 

  34. Lieberman AF, Ippen CG, Van Horn PJ (2006) Child–parent psychotherapy: 6 month follow-up of a randomized controlled trial. J Am Acad Child Adolesc Psychiatry 45:913–918

    Article  PubMed  Google Scholar 

  35. Luby JL, Belden AC, Pautsch J, Si X, Spitznagel E (2009) The clinical significance of preschool depression: Impairment in functioning and clinical markers of the disorder. J Affect Disord 112:111–119

    Article  PubMed  Google Scholar 

  36. Luby JL, Heffelfinger A, Mrakotsky C, Brown K, Hessler M, Spitznagel E (2003) Alterations in stress cortisol reactivity in depressed preschoolers relative to psychiatric and no-disorder comparison groups. Arch Gen Psychiatry 60:1248–1255

    Article  PubMed  Google Scholar 

  37. Luby JL, Heffelfinger A, Mrakotsky C, Hessler M, Brown K, Hildebrand T (2002) Preschool major depressive disorder: preliminary validation for developmentally modified DSM-IV criteria. J Am Acad Child Adolesc Psychiatry 41:928–937

    Article  PubMed  Google Scholar 

  38. McIntosh AM, Holmes S, Gleeson S, Burns JK, Hodges AK, Byrne MM, Dobbie R, Miller P, Lawrie SM, Johnstone EC (2002) Maternal recall bias, obstetric history and schizophrenia. Br J Psychiatry 181:520–525

    Article  PubMed  CAS  Google Scholar 

  39. Perna L, Bolte G, Mayrhofer H, Spies G, Mielck A (2010) The impact of the social environment on children’s mental health in a prosperous city: an analysis with data from the city of Munich. BMC Public Health 10:199–209

    Article  PubMed  Google Scholar 

  40. Rescorla L, Achenbach T, Ivanova MY, Dumenci L, Almqvist F, Bilenberg N, Bird H, Chen W, Dobrean A, Döpfner M, Erol N, Fombonne E, Fonseca A, Frigerio A, Grietens H, Hannesdottir H, Kanbayashi Y, Lambert M, Larsson B, Leung P, Liu X, Minaei A, Mulatu, Novik TS, Oh K-J, Roussos A, Sawyer M, Simsek Z, Steinhausen H-C, Weintraub S, Weisz J, Metzke CW, Wolanczyk T, Yang H-J, Zilber N, Zukauskiene R, Verhulst F (2007) Behavioral and emotional problems reported by parents of children ages 6 to 16 in 31 societies. J Emot Behav Disord 15:130

    Article  Google Scholar 

  41. SAS Institute Inc. (2008) SAS 9.2. SAS, Cary, USA

  42. Scheeringa MS, Peebles CD, Cook CA, Zeanah CH (2001) Toward establishing procedural, criterion, and discriminant validity for PTSD in early childhood. J Am Acad Child Adolesc Psychiatry 40:52–60

    Article  PubMed  CAS  Google Scholar 

  43. Scheeringa MS, Zeanah CH (2008) Reconsideration of Harm’s Way: onsets and comorbidity patterns of disorders in preschool children and their caregivers following Hurricane Katrina. J Clin Child Adolesc Psychol 37:508–518

    Article  PubMed  Google Scholar 

  44. Scheeringa MS, Zeanah CH, Myers L, Putnam F (2004) Heart period and variability findings in preschool children with posttraumatic stress symptoms. Biol Psychiatry 55:685–691

    Article  PubMed  Google Scholar 

  45. Slemming K, Sørensen M, Thomsen P, Obel C, Henriksen T, Linnet K (2010) The association between preschool behavioural problems and internalizing difficulties at age 10–12 years. Eur Child Adolesc Psychiatry 19:787

    Article  PubMed  Google Scholar 

  46. Sourander A (2001) Emotional and behavioural problems in a sample of Finnish three-year-olds. Eur Child Adolesc Psychiatry 10:98–104

    Article  PubMed  CAS  Google Scholar 

  47. SPSS Statistics (2008) SPSS Statistics 17.0. SPSS, Chicago, USA

  48. Thompson MJJ, Stevenson J, Sonuga-Barke E, Nott P (1996) Mental health of preschool children and their mothers in a mixed urban/rural population: I. Prevalence and ecological factors. Br J Psychiatry 168:16

    Article  PubMed  CAS  Google Scholar 

  49. U.S. Census Bureau (2011) Child care arrangements of preschoolers by type of arrangement 1991–2005. http://www.census.gov/prod/2010pubs/p70-121.pdf. Accessed 18 Aug 2011

  50. Wakschlag LS, Keenan K (2001) Clinical significance and correlates of disruptive behavior in environmentally at-risk preschoolers. J Clin Child Psychol 30:262

    Article  PubMed  CAS  Google Scholar 

  51. Wakschlag LS, Leventhal BL, Thomas J, Pine DS, Narrow WE, First MB, Sirovatka PJ, Regier DA (2007) Disruptive behavior disorders and ADHD in preschool children: characterizing heterotypic continuities for a developmentally informed nosology for DSM-V. In: Rieger D, First MB, Narrow WE (eds) Age and gender considerations in psychiatric diagnosis: a research agenda for DSM-V. American Psychiatric Publishing, Inc., Arlington, p 243

    Google Scholar 

  52. Weissman MM, Pilowsky DJ, Wickramaratne PJ, Talati A, Wisniewski SR, Fava M, Hughes CW, Garber J, Malloy E, King CA, Cerda G, Sood AB, Alpert JE, Trivedi MH, Rush AJ, for the SDCT (2006) Remissions in maternal depression and child psychopathology: a STAR*D-Child Report. JAMA 295:1389–1398

  53. Zeanah CH, Egger HL, Smyke AT, Nelson CA, Fox NA, Marshall PJ, Guthrie D (2009) Institutional rearing and psychiatric disorders in Romanian preschool children. Am J Psychiatry 166:777–785

    Article  PubMed  Google Scholar 

  54. Zeanah CH, Boris NW, Larrieu JA (1997) Infant development and developmental risk: a review of the past 10 years. J Am Acad Child Adolesc Psychiatry 36:165–176

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

The authors express their appreciation to the families and staff at Dr. Victor Gomoiu Children’s Hospital and the Marie Curie Children’s Hospital. This study was funded by the Fundatia Tulane, Bucharest, Romania

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None of the authors have competing interests related to this study.

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Correspondence to Mary Margaret Gleason.

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Gleason, M.M., Zamfirescu, A., Egger, H.L. et al. Epidemiology of psychiatric disorders in very young children in a Romanian pediatric setting. Eur Child Adolesc Psychiatry 20, 527–535 (2011). https://doi.org/10.1007/s00787-011-0214-0

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  • DOI: https://doi.org/10.1007/s00787-011-0214-0

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