Skip to main content
SpringerLink
Log in

Validity of childhood disintegrative disorder apart from autistic disorder with speech loss

  • ORIGINAL CONTRIBUTION
  • Published:
European Child & Adolescent Psychiatry Aims and scope Submit manuscript

Abstract.

In order to test clinical validity of DSM-IV childhood disintegrative disorder (CDD), 10 CDD children (mean age = 8.2 years, SD = 3.8; 7 male and 3 female) and 30 age- and gender-matched children with DSM-IV autistic disorder (AD) with speech loss (SL) (ADSL) were compared on 24 variables not directly related to CDD criteria. Compared with the ADSL children, the CDD children showed fearfulness significantly more frequently during the period of SL; displayed epilepsy significantly more frequently and stereotypy significantly more prominently at first visit on average about 6 years after SL; and had significantly less uneven intellectual profile at first visit to support the validity of CDD to a certain extent. No significant difference in the retardation level at first visit between the two groups suggested no worse short-term outcome in CDD than ADSL, although a long-term prospective study to compare them from infancy is needed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. American Psychiatric Association (1980) Diagnostic and Statistical Manual of Mental Disorders, 3rd edn. American Psychiatric Association, Washington, DC

  2. American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders, 4th edn. American Psychiatric Association, Washington, DC

  3. American Psychiatric Association (2000) Autistic disorder. In: Diagnostic and Statistical Manual of Mental Disorders, 4th edn. text revision. American Psychiatric Association, Washington, DC, pp 70–75

  4. Bartak L, Rutter M (1976) Differences between mentally retarded and normally intelligent autistic children. J Autism Childhood Schizophr 6:109–120

    CAS  Google Scholar 

  5. Bodfish JW, Symons FJ, Parker DE, Lewis MH (2000) Varieties of repetitive behavior in autism: Comparisons to mental retardation. J Autism Devel Disord 30:237–243

    Article  CAS  Google Scholar 

  6. Brown J, Prelock PA (1995) The impact of regression on language development in autism. J Autism Devel Disord 25:305–309

    CAS  Google Scholar 

  7. Burd L, Ivey M, Barth A, Kerbeshian J (1998) Two males with childhood disintegrative disorder: A prospective 14-year outcome study. Devel Med Child Neurol 40:702–707

    CAS  Google Scholar 

  8. Chakrabarti S, Fombonne E (2001) Pervasive developmental disorders in preschool children. JAMA 285:3093–3099

    Article  CAS  PubMed  Google Scholar 

  9. Evans-Jones LG, Rosenbloom L (1978) Disintegrative psychosis in childhood. Devel Med Child Neurol 20:462–470

    CAS  Google Scholar 

  10. Heller T (1908) Über Dementia infantilis: Verblödungsprozess im Kindesalter. Zeitschrift für die Erforschung und Behandlung des Jugendlichen Schwachsinns 2:17–28

    Google Scholar 

  11. Hill AE, Rosenbloom L (1986) Disintegrative psychosis of childhood: Teenage follow-up. Devel Med Child Neurol 28:34–40

    CAS  Google Scholar 

  12. Hoshino Y, Kaneko M, Yashima Y, Kumashiro H, Volkmar FR, Cohen DJ (1987) Clinical features of autistic children with setback course in their infancy. Japanese J Psychiatry Neurol 41:237–246

    CAS  Google Scholar 

  13. Kobayashi R, Murata T (1998) Setback phenomenon in autism and long-term prognosis. Acta Psychiatr Scand 98:296–303

    CAS  PubMed  Google Scholar 

  14. Kurita H (1985) Infantile autism with speech loss before the age of thirty months. J Am Acad Child Psychiatry 24:191–196

    CAS  PubMed  Google Scholar 

  15. Kurita H (1988) The concept and nosology of Heller’s syndrome: Review of articles and report of two cases. Japanese J Psychiatry Neurol 42:785–793

    Google Scholar 

  16. Kurita H, Miyake Y, Katsuno K (1989) Reliability and validity of the Childhood Autism Rating Scale–Tokyo Version (CARS-TV). J Autism Devel Disord 19:389–396

    CAS  Google Scholar 

  17. Kurita H, Kita M, Miyake Y (1992) A comparative study of development and symptoms among disintegrative psychosis and infantile autism with and without speech loss. J Autism Devel Disord 22:175–188

    CAS  Google Scholar 

  18. Lockyer L, Rutter M (1970) A five- to fifteen-year follow-up study of infantile psychosis. IV.Patterns of cognitive ability. Br J Soc Clin Psychol 9:152–163

    CAS  PubMed  Google Scholar 

  19. Malhotra S, Singh SP (1993) Disintegrative psychosis of childhood: An appraisal and case study. Acta Paedopsychiatr 56:37–40

    CAS  PubMed  Google Scholar 

  20. Malhotra S, Gupta N (2002) Childhood disintegrative disorder: Re-examination of the current concept. Eur Child Adolesc Psychiatry 11:108–114

    Article  CAS  PubMed  Google Scholar 

  21. Mouridsen SE, Rich B, Isager T (1998) Validity of childhood disintegrative psychosis: General findings of a long-term follow-up study. Br J Psychiatry 172:263–267

    CAS  PubMed  Google Scholar 

  22. Rogers SJ, DiLalla DL (1990) Age of symptom onset in young children with pervasive developmental disorders. J Am Acad Child Adolesc Psychiatry 29:863–872

    CAS  PubMed  Google Scholar 

  23. Schopler E, Reichler RJ, DeVellis RF, Daly K (1980) Toward objective classification of childhood autism: Childhood Autism Rating Scale (CARS). J Autism Devel Disord 10:91–103

    CAS  Google Scholar 

  24. Shah A, Frith U (1983) An islet of ability in autistic children: A research note. J Child Psychol Psychiatry 24:613–620

    CAS  PubMed  Google Scholar 

  25. Tuchman RF, Rapin I (1997) Regression in pervasive developmental disorders: Seizures and epileptiform electroencephalogram correlates. Pediatrics 99:560–566

    Article  CAS  PubMed  Google Scholar 

  26. Volkmar FR, Cohen DJ (1989) Disintegrative disorder or “late onset” autism. J Child Psychol Psychiatry 30:717–724

    CAS  PubMed  Google Scholar 

  27. Volkmar FR (1992) Childhood disintegrative disorder: Issues for DSM-IV. J Autism Devel Disord 22:625–642

    CAS  Google Scholar 

  28. Volkmar FR, Rutter M (1995) Childhood disintegrative disorder: Results of the DSM-IV autism field trial. J Am Acad Child Adolesc Psychiatry 34:1092–1095

    Article  CAS  PubMed  Google Scholar 

  29. World Health Organization (1977) International Classification of Diseases 1975 revision Vol. 1. World Health Organization, Geneva

  30. World Health Organization (1989) ICD-10 Chapter V: Mental and Behavioural Disorders: Diagnostic Criteria for Research (April 1989 draft for field trials). World Health Organization, Geneva

  31. World Health Organization (1993) The ICD-10 Classification of Mental and Behavioural Disorders: Diagnostic Criteria for Research. World Health Organization, Geneva

Download references

Author information

Authors and Affiliations

  1. Dept. of Mental Health, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo Bunkyo-ku, Tokyo 113-0033, Japan

    Hiroshi Kurita MD, Tomonori Koyama MS & Yutaro Setoya PhD

  2. Dept. of Psychiatry, Graduate School of Medicine, University of Shinshyu, Matsumoto, Japan

    Kaoru Shimizu MD

  3. Faculty of Law, University of Senshu, Tokyo, Japan

    Hirokazu Osada PhD

Authors
  1. Hiroshi Kurita MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tomonori Koyama MS
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yutaro Setoya PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kaoru Shimizu MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Hirokazu Osada PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hiroshi Kurita MD.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kurita, H., Koyama, T., Setoya, Y. et al. Validity of childhood disintegrative disorder apart from autistic disorder with speech loss. European Child & Adolescent Psychiatry 13, 221–226 (2004). https://doi.org/10.1007/s00787-004-0397-8

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00787-004-0397-8

Key words

Search

Navigation