Abstract
LSVT-BIG is an exercise for patients with Parkinson’s disease (PD) comprising of 16 1-h sessions within 4 weeks. LSVT-BIG was compared with a 2-week short protocol (AOT-SP) consisting of 10 sessions with identical exercises in 42 patients with PD. UPDRS-III-score was reduced by −6.6 in LSVT-BIG and −5.7 in AOT-SP at follow-up after 16 weeks (p < 0.001). Measures of motor performance were equally improved by LSVT-BIG and AOT-SP but high-intensity LSVT-BIG was more effective to obtain patient-perceived benefit.
References
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Acknowledgments
We thank Deutsche Parkinson Gesellschaft for financial and organizational support. We also thank Heike Unger and physiotherapists in Beelitz-Heilstätten for skillfully exercising participants. This work was supported by an unrestricted Grant from Deutsche Parkinson Gesellschaft.
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The authors have no financial disclosures to make and no conflict of interest to report with respect to the research reported in this manuscript.
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Ebersbach, G., Grust, U., Ebersbach, A. et al. Amplitude-oriented exercise in Parkinson’s disease: a randomized study comparing LSVT-BIG and a short training protocol. J Neural Transm 122, 253–256 (2015). https://doi.org/10.1007/s00702-014-1245-8
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DOI: https://doi.org/10.1007/s00702-014-1245-8