Abstract
LSVT-BIG is an exercise for patients with Parkinson’s disease (PD) comprising of 16 1-h sessions within 4 weeks. LSVT-BIG was compared with a 2-week short protocol (AOT-SP) consisting of 10 sessions with identical exercises in 42 patients with PD. UPDRS-III-score was reduced by −6.6 in LSVT-BIG and −5.7 in AOT-SP at follow-up after 16 weeks (p < 0.001). Measures of motor performance were equally improved by LSVT-BIG and AOT-SP but high-intensity LSVT-BIG was more effective to obtain patient-perceived benefit.
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References
Ebersbach G, Ebersbach A, Edler D, Kaufhold O, Kusch M, Kupsch A et al (2010) Comparing exercise in Parkinson’s disease—the Berlin BIG study. Mov Disord 25:1902–1908
Farley BG, Fox CM, Ramig L, Farland DC (2008) Intensive amplitude-specific therapeutic approaches for Parkinson’s disease. Topics Geriatr Rehabil 24:99–114
Hughes AJ, Ben-Shlomo Y, Daniel SE, Lees AJ (1992) What features improve the accuracy of clinical diagnosis in Parkinson’s disease: a clinicopathologic study. Neurology 42:1142–1146
Jenkinson C, Fitzpatrick R, Peto V, Greenhall R, Hyman N (1997) The Parkinson’s disease questionnaire (PDQ-39): development and validation of a Parkinson’s disease summary index score. Age Ageing 26:353–357
Liotti M, Ramig LO, Vogel D, New P, Cook CI, Ingham RJ et al (2003) Hypophonia in Parkinson’s disease: neural correlates of voice treatment revealed by PET. Neurology 60:432–440
Mathiowetz V, Volland G, Kashman N, Weber K (1985) Adult norms for the box and block test of manual dexterity. Am J Occup Ther 39:386–391
Morris ME, Iansek R, Matyas TA, Summers JJ (1996) Stride length regulation in Parkinson’s disease. Normalisation strategies and underlying mechanisms. Brain 119:551–568
Rochester L, Baker K, Hetherington V, Jones D, Willems AM, Kwakkel G et al (2010) Evidence for motor learning in Parkinson’s disease: acquisition, automaticity and retention of cued gait performance after training with external rhythmical cues. Brain Res 1319:103–111
Schwesig R, Kauert R, Wust S, Leuchte S (2010) Reliability of the novel gait analysis system RehaWatch. Biomed Tech (Berl) 55:109–115
Tickle-Degnen L, Ellis T, Saint-Hilaire MH, Thomas CA, Wagenaar RC (2010) Self-management rehabilitation and health-related quality of life in Parkinson’s disease: a randomized controlled trial. Mov Disord 25:194–204
Tomlinson CL, Patel S, Meek C, Herd CP, Clarke CE, Stowe R (2012) Physiotherapy intervention in Parkinson’s disease: systematic review and meta-analysis. BMJ 345:e5004. doi:10.1136/bmj.e5004
Wu T, Hallett M (2008) Neural correlates of dual task performance in patients with Parkinson’s disease. J Neurol Neurosurg Psychiatry 79:760–766
Acknowledgments
We thank Deutsche Parkinson Gesellschaft for financial and organizational support. We also thank Heike Unger and physiotherapists in Beelitz-Heilstätten for skillfully exercising participants. This work was supported by an unrestricted Grant from Deutsche Parkinson Gesellschaft.
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The authors have no financial disclosures to make and no conflict of interest to report with respect to the research reported in this manuscript.
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Ebersbach, G., Grust, U., Ebersbach, A. et al. Amplitude-oriented exercise in Parkinson’s disease: a randomized study comparing LSVT-BIG and a short training protocol. J Neural Transm 122, 253–256 (2015). https://doi.org/10.1007/s00702-014-1245-8
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DOI: https://doi.org/10.1007/s00702-014-1245-8