Abstract
The aim of this exploratory study was to describe quality of life (QL) domains and independence in activities of daily living (ADL) in patients (n=86) undergoing surgery for colorectal cancer. The patients were consecutively included, and two validated instruments, EORTC's QLQ-C30 and the Katz'/Hulter Åsberg Index of Independence in ADL, were used preoperatively and at follow-up after 5–8 months. The findings were related to tumour localization, tumour burden according to Dukes' classification and to preoperative radiotherapy treatment. The results showed a significant improvement in the patients' scores for emotional functioning, appetite and global QL and a significant increase in financial impact at follow-up. The patients with colon cancer (n=39) also had significantly less pain and less constipation at follow-up compared with preoperatively than did patients with rectal cancer (n=47). The patients with rectal cancer, having undergone preoperative radiotherapy treatment, had significantly lower confidence intervals for means (95%) on the physical functioning and role functioning scales at follow-up versus preoperatively. Total ADL independence decreased from 70% of the patients preoperatively to 57% at follow-up, and independence in instrumental ADL decreased from 72% to 64% of the patients. No patient was dependent in personal ADL preoperatively, while 3% were dependent at follow-up. A lower mean score of global QL was found preoperatively and at follow-up for patients who were dependent in ADL than for patients who were independent in ADL. The instruments were found useful for evaluating individual patients in clinical practice.
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Ulander, K., Jeppsson, B. & Grahn, G. Quality of life and independence in activities of daily living preoperatively and at follow-up in patients with colorectal cancer. Support Care Cancer 5, 402–409 (1997). https://doi.org/10.1007/s005200050099
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DOI: https://doi.org/10.1007/s005200050099