Abstract
Purpose
To examine the effect of physical activity on the physical and psychosocial symptoms of lung cancer survivors.
Methods
A longitudinal design was used in this study. Participants were recruited from the chest and surgical departments of medical centers in Taiwan. The instruments used were the Godin Leisure-Time Exercise Questionnaire and the Taiwanese version of the M.D. Anderson Symptom Inventory.
Results
In total, 185 survivors were followed up for 6 months (response rate 66 %). Disturbed sleep was the most prevalent symptom in the participants. A generalized estimating equation (GEE) method was employed to analyze the relationships among intensity of physical activity, symptom severity, and symptom interference in the daily life of the participants. Regarding symptom severity, significant differences were observed in fatigue, drowsiness, and disturbed sleep between the participants who engaged in moderate physical activity and those who did not engage in any physical activity. Regarding symptom interference, the participants who engaged in light physical activity experienced a significantly lower level of symptom interference than did those with a sedentary lifestyle.
Conclusion
This is the first study to explore the role of physical activity in alleviating symptoms in lung cancer survivors by using the GEE method. The results suggest that physical activity plays an essential role in alleviating the physical and psychological symptoms of lung cancer survivors.
Similar content being viewed by others
References
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61:69–90
Chang JA, Lin CC (2009) A longitudinal study of the role of patient-reported outcomes on survival prediction of palliative cancer inpatients in Taiwan. Support Care Cancer 17:1285–1294
Hwang CL, Yu CJ, Shih JY, Yang PC, Wu YT (2012) Effects of exercise training on exercise capacity in patients with non-small cell lung cancer receiving targeted therapy. Support Care Cancer 20:3169–3177
Stevinson C, Faught W, Steed H et al (2007) Associations between physical activity and quality of life in ovarian cancer survivors. Gynecol Oncol 106:244–250
Peddle CJ, Au HJ, Courneya KS (2008) Associations between exercise, quality of life, and fatigue in colorectal cancer survivors. Dis Colon Rectum 51:1242–1248
Mishra SI, Scherer RW, Snyder C, Geigle PM, Berlanstein DR, Topaloglu O (2012) Exercise interventions on health-related quality of life for people with cancer during active treatment. Clin Otolaryngol 37:390–392
Cheung WY, Barmala N, Zarinehbaf S, Rodin G, Le LW, Zimmermann C (2009) The association of physical and psychological symptom burden with time to death among palliative cancer outpatients. J Pain Symptom Manag 37:297–304
Chow E, Fung K, Panzarella T, Bezjak A, Danjoux C, Tannock I (2002) A predictive model for survival in metastatic cancer patients attending an outpatient palliative radiotherapy clinic. Int J Radiat Oncol Biol Phys 53:1291–1302
Luoma ML, Hakamies-Blomqvist L, Sjöström J et al (2003) Prognostic value of quality of life scores for time to progression (TTP) and overall survival time (OS) in advanced breast cancer. Eur J Cancer 39:1370–1376
Knobf MT, Thompson AS, Fennie K, Erdos D (2014) The effect of a community-based exercise intervention on symptoms and quality of life. Cancer Nurs 37:E43–E50
Alfano CM, Smith AW, Irwin ML et al (2007) Physical activity, long-term symptoms, and physical health-related quality of life among breast cancer survivors: a prospective analysis. J Cancer Surviv 1:116–128
Yang CY, Tsai JC, Huang YC, Lin CC (2011) Effects of a home-based walking program on perceived symptom and mood status in postoperative breast cancer women receiving adjuvant chemotherapy. J Adv Nurs 67:158–168
Stevinson C, Steed H, Faught W et al (2009) Physical activity in ovarian cancer survivors: associations with fatigue, sleep, and psychosocial functioning. Int J Gynecol Cancer 19:73–78
Cheville AL, Kollasch J, Vandenberg J et al (2013) A home-based exercise program to improve function, fatigue, and sleep quality in patients with stage IV lung and colorectal cancer: a randomized controlled trial. J Pain Symptom Manag 45:811–821
Tang MF, Liou TH, Lin CC (2010) Improving sleep quality for cancer patients: benefits of a home-based exercise intervention. Support Care Cancer 18:1329–1339
Payne JK, Held J, Thorpe J, Shaw H (2008) Effect of exercise on biomarkers, fatigue, sleep disturbances, and depressive symptoms in older women with breast cancer receiving hormonal therapy. Oncol Nurs Forum 35:635–642
Sprod LK, Mohile SG, Demark-Wahnefried W et al (2012) Exercise and cancer treatment symptoms in 408 newly diagnosed older cancer patients. J Geriatr Oncol 3:90–97
Rogers LQ, Markwell SJ, Courneya KS, McAuley E, Verhulst S (2011) Physical activity type and intensity among rural breast cancer survivors: patterns and associations with fatigue and depressive symptoms. J Cancer Surviv 5:54–61
Humpel N, Iverson DC (2010) Sleep quality, fatigue and physical activity following a cancer diagnosis. Eur J Cancer Care 19:761–768
Godin G, Shephard RJ (1985) A simple method to assess exercise behavior in the community. Can J Appl Sport Sci 10:141–146
Jacobs DR Jr, Ainsworth BE, Hartman TJ, Leon AS (1993) A simultaneous evaluation of 10 commonly used physical activity questionnaires. Med Sci Sports Exerc 25:81–91
Miller DJ, Freedson PS, Kline GM (1994) Comparison of activity levels using the Caltrac accelerometer and five questionnaires. Med Sci Sports Exerc 26:376–382
Rock C, Doyle C, Demark-Wahnefried W, Meyerhardt J, Courneya K, Schwartz A, Bandera E, Hamilton K, Grant B, McCullough M, Byers T, Gansler T (2012) Nutrition and physical activity guidelines for cancer survivors. CA Cancer J Clin 62:243–274
Pate RR, Pratt M, Blair SN et al (1995) Physical activity and public health: a recommendation from the centers for disease control and prevention and the American college of sports medicine. J Am Med Assoc 273:402–407
Lin CC, Chang AP, Cleeland CS, Mendoza TR, Wang XS (2007) Taiwanese version of the M. D. anderson symptom inventory: symptom assessment in cancer patients. J Pain Symptom Manag 33:180–188
Cleeland CS, Mendoza TR, Wang XS et al (2000) Assessing symptom distress in cancer patients: the M. D. Anderson Symptom Inventory. Cancer 89:1634–1646
Cohen J (1992) Statistical power analysis in the behavioral sciences. Lawrence Erlbaum, Hillsdale
Lin YY, Wu YC, Rau KM, Lin CC (2013) Effects of physical activity on the quality of life in taiwanese lung cancer patients receiving active treatment or off treatment. Cancer Nurs 36:E35–E41
Gooneratne NS, Dean GE, Rogers AE, Nkwuo JE, Coyne JC, Kaiser LR (2007) Sleep and quality of life in long-term lung cancer survivors. Lung Cancer 58:403–410
Ginsburg ML, Quirt C, Ginsburg AD, MacKillop WJ (1995) Psychiatric illness and psychosocial concerns of patients with newly diagnosed lung cancer. CMAJ 152:701–708
Baker F, Denniston M, Smith T, West MM (2005) Adult cancer survivors: how are they faring? Cancer 104:2565–2576
Wang SY, Tsai CM, Chen BC, Lin HC, Lin CC (2008) Symptom clusters and relationships to symptom interference with daily life in Taiwanese lung cancer patients. J Pain Symptom Manag 35:258–266
Jones LW, Eves ND, Peterson BL et al (2008) Safety and feasibility of aerobic training on cardiopulmonary function and quality of life in postsurgical nonsmall cell lung cancer patients: a pilot study. Cancer 113:3430–3439
Riesenberg H, Lübbe AS (2010) In-patient rehabilitation of lung cancer patients—a prospective study. Support Care Cancer 18:877–882
Karvinen KH, Courneya KS, North S, Venner P (2007) Associations between exercise and quality of life in bladder cancer survivors: a population-based study. Cancer Epidemiol Biomarkers Prev 16:984–990
Peddle-McIntyre C, Bell G, Fenton D, McCargar L, Courneya K (2012) Feasibility and preliminary efficacy of progressive resistance exercise training in lung cancer survivors. Lung Cancer 75:126–132
Jones LW, Eves ND, Spasojevic I, Wang F, Il'yasova D (2011) Effects of aerobic training on oxidative status in postsurgical non-small cell lung cancer patients: a pilot study. Lung Cancer 72:46–51
Buffart LM, Galvao DA, Brug J, Chinapaw MJM, Newton RU (2014) Evidence-based physical activity guidelines for cancer survivors: current guidelines, knowledge gaps and future research directions. Cancer Treat Rev 40:327–340
Acknowledgments
The authors thank all participants of this study.
Conflict of interest
The authors have no conflicts of interest or financial relationships to disclose.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Lin, YY., Rau, KM. & Lin, CC. Longitudinal study on the impact of physical activity on the symptoms of lung cancer survivors. Support Care Cancer 23, 3545–3553 (2015). https://doi.org/10.1007/s00520-015-2724-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00520-015-2724-7