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Quality of life in children with end-stage renal disease based on a PedsQL ESRD module

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Abstract

Background

Health-related quality of life (HRQOL) is an essential subject for children with end-stage renal disease (ESRD) and their families.

Methods

We performed a cross-sectional investigation of HRQOL in children undergoing renal replacement therapies, such as dialysis and renal transplantation, using the 34-item Pediatric Quality of Life Inventory 3.0 End-Stage Renal Disease (PedsQL 3.0 ESRD) module. We assessed 92 ESRD patients aged 2–18 from four Korean university hospitals.

Results

The male:female ratio was 44:48, and the most common cause of ESRD was chronic glomerulonephritis. Fifty-five children were treated by dialysis, and 37 received renal transplantation. Transplant patients had better HRQOL than dialysis patients in two domains in parent proxy reports: “About my kidney disease” and “Worry.” In child self-reports, transplant patients had better HRQOL than dialysis patients in one domain: Treatment problems. However, there were no significant differences in total QOL scores between peritoneal dialysis (PD) and transplant patients in child self-reports. In addition, there were differences in the ESRD module scores between child self- and parent proxy reports. Children usually reported better QOL than their parents. Child self-reports showed significantly higher QOL scores than parent proxy reports in the domains of General fatigue, Family & peer interaction, and Worry. Children on PD self-reported a significantly higher QOL than children on hemodialysis (HD).

Conclusions

The PedsQL 3.0 ESRD module may be useful as an ESRD-specific instrument to evaluate HRQOL in children; however, a larger, longitudinal prospective study is warranted.

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Authors and Affiliations

  1. Department of Preventive Medicine and Institute of Health Sciences, Gyeongsang National University Hospital, Jinju, Republic of Korea

    Ki-Soo Park

  2. Department of Pediatrics, Kyungpook National University Hospital, 50, Samduk Dong 2Ga, Jung Gu, Daegu, 700-721, Republic of Korea

    Young Ju Hwang, Min Hyun Cho & Cheol Woo Ko

  3. Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, Republic of Korea

    Il Soo Ha, Hee Gyung Kang & Hae Il Cheong

  4. Department of Pediatrics, Asan Medical Center, Seoul, Republic of Korea

    Young Seo Park, Yoon Jung Lee & Joo Hoon Lee

  5. Department of Pediatrics, Samsung Medical Center, Seoul, Republic of Korea

    Hee Yeon Cho

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  1. Ki-Soo Park
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  2. Young Ju Hwang
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  3. Min Hyun Cho
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  4. Cheol Woo Ko
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  8. Young Seo Park
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Correspondence to Min Hyun Cho.

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Park, KS., Hwang, Y.J., Cho, M.H. et al. Quality of life in children with end-stage renal disease based on a PedsQL ESRD module. Pediatr Nephrol 27, 2293–2300 (2012). https://doi.org/10.1007/s00467-012-2262-1

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  • DOI: https://doi.org/10.1007/s00467-012-2262-1

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