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Urinary tract infections in children with spina bifida: an inventory of 41 European centers

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Abstract

The introduction of clean intermittent catheterization (CIC) in 1972 and low-dose chemoprophylaxis (LDCP, antibiotic prophylaxis), anticholinergic medication and urological surgery in the mid-1980s has improved the long-term outcome of renal function in children with neurogenic bladder sphincter dysfunction (NBSD) due to spina bifida (SB). We have conducted a European survey of the protocols for diagnosing and treating urinary tract infections (UTIs) in these children, using a web-based questionnaire. The responses from 41 centers in 14 European countries confirm that although most centers have standardized protocols for treating UTIs, there is no consensus among European centers in terms of protocols for preventing, diagnosing and treating UTIs in children with NBSD and for CIC.

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Abbreviations

CIC:

clean intermittent catheterization

LDCP:

low dose chemoprophylaxis, antibiotic prophylaxis

NBSD:

neurogenic bladder sphincter dysfunction

SB:

spina bifida

UTI:

urinary tract infection

VUR:

vesico-ureteral reflux

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Authors and Affiliations

  1. Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands

    Bas S. H. J. Zegers, Pauline L. H. Winkler–Seinstra, Tom V. P. M. de Jong, Jan L. L. Kimpen & Catharine C. E. de Jong–de Vos van Steenwijk

  2. Department of Pediatrics, Máxima Medical Center, Postbox 7777, 5500 MB, Veldhoven, The Netherlands

    Bas S. H. J. Zegers

  3. Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands

    Cuno S. P. M. Uiterwaal

Authors
  1. Bas S. H. J. Zegers
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  2. Pauline L. H. Winkler–Seinstra
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  3. Cuno S. P. M. Uiterwaal
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  4. Tom V. P. M. de Jong
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  5. Jan L. L. Kimpen
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  6. Catharine C. E. de Jong–de Vos van Steenwijk
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Correspondence to Bas S. H. J. Zegers.

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Zegers, B.S.H.J., Winkler–Seinstra, P.L.H., Uiterwaal, C.S.P.M. et al. Urinary tract infections in children with spina bifida: an inventory of 41 European centers. Pediatr Nephrol 24, 783–788 (2009). https://doi.org/10.1007/s00467-008-1067-8

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  • DOI: https://doi.org/10.1007/s00467-008-1067-8

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