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Motor performance, exercise tolerance, and health-related quality of life in children on dialysis

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Abstract

In contrast to the adult population, little is known regarding health-related quality of life and exercise tolerance in children with end-stage renal disease (ESRD) undergoing chronic intermittent hemodialysis. We designed a pilot study to investigate whether research into this area is indicated. The aim of this study was to describe the motor skills, exercise tolerance, and health-related quality of life in children with ESRD. The study population consisted of ten hemodialysis patients (aged 7–16 years). In eight children motor proficiency according to Bruininks-Oseretsky was determined. In all ten children a progressive exercise test on a treadmill was performed. The results were compared with an age-matched healthy reference group. Nine children filled in the TNO-AZL Child Quality of Life (TACQOL) scoring list. One child had a markedly reduced fine motor skills capacity; another five children scored ≤−2 SD compared with healthy children in gross motor skills. Seven children showed a diminished VO2max (per kilogram body weight); six of these are physically inactive. Four of these seven children did not sustain the maximum workload. The self-assessed physical and mental health of children on dialysis seems comparable to the general population. We found no correlation between exercise performance or motor skills and hemoglobin levels, Kt/V, and time on dialysis. In conclusion, in this study most children had a reduced exercise tolerance and gross motor skills. There was no difference in fine motor skills. Pediatric dialysis patients report a good health-related quality of life.

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References

  1. Brodin E, Ljungman S, Hedberg M, Sunnerhagen KS (2001) Physical activity, muscle performance and quality of life in patients treated with chronic peritoneal dialysis. Scand J Urol Nephrol 35:71–78

    Article  CAS  PubMed  Google Scholar 

  2. Johansen KL, Chertow GM, Mulligen K, Carey S, Schoenfeld PY, Kent-Braun JA (2000) Physical activity levels in patients on hemodialysis and healthy sedentary controls. Kidney Int 57:2564–2570

    Article  CAS  PubMed  Google Scholar 

  3. Fitts SS, Guthrie MR, Blagg CR (1999) Exercise coaching and rehabilitation counseling improve quality of life for predialysis and dialysis patients. Nephron 82:115–121

    Article  CAS  PubMed  Google Scholar 

  4. Mittal SK, Ahern L, Flaster E, Maesaka JK, Fishbane S (2001) Self-assessed physical and mental function of haemodialysis patients. Nephrol Dial Transplant 16:1387–1394

    Article  CAS  PubMed  Google Scholar 

  5. Kong CH, Tattersall JE, Greenwood RN, Farrington K (1999) The effect of exercise during haemodialysis on solute removal. Nephrol Dial Transplant 14:2927–2931

    Article  CAS  PubMed  Google Scholar 

  6. Brass EP, Adler S, Sietsema KE, Hiatt WR, Orlando AM, Amato A (2001) Intravenous l -carnitine increases plasma carnitine, reduces fatigue, and may preserve exercise capacity in haemodialysis patients. Am J Kidney Dis 37:1018–1028

    CAS  PubMed  Google Scholar 

  7. Tawney KW, Tawney PJW, Hladik G, Hogan SL, Falk RJ, Weaver C, Moore DT, Lee MY (2000) The Life Readiness Program: a physical rehabilitation program for patients on hemodialysis. Am J Kidney Dis 36:581–591

    CAS  PubMed  Google Scholar 

  8. Chi-yuen Lo, Leonard L, Wai-kai L, (1998) Benefits of exercise training in patients on continuous ambulatory peritoneal dialysis. Am J Kidney Dis 32:1011–1018

    PubMed  Google Scholar 

  9. Suzuki M, Tsutsui M, Yokoyama A, Hirasawa Y (1995) Normalization of hematocrit with recombinant human erythropietin in chronic hemodialysis patients does not fully improve their exercise tolerance abilities. Artif Organs 12:1258–1261

    Google Scholar 

  10. Painter P (1994) The importance of exercise training in rehabilitation of patients with end-stage renal disease. Am J Kidney Dis 24:S2–S9

    CAS  PubMed  Google Scholar 

  11. Kutner NG, Zhang R, McClellan WM (2000) Patient-reported quality of life early in dialysis treatment: effects associated with usual exercise activity. Nephrol Nurs J 27:357–367

    CAS  PubMed  Google Scholar 

  12. Painter P, Moore G, Carlson L, Paul S, Myll J, Phillips W, Haskell W (2002) Effects of exercise training plus normalisation of hematocrit on exercise capacity and health-related quality of life. Am J Kidney Dis 39:257–265

    PubMed  Google Scholar 

  13. Capodaglio EM, Villa G, Jurisic D, Salvadeo A (1998) Levels of sustainable aerobic workload in dialysis patients. Int J Artif Organs 21:391–397

    CAS  PubMed  Google Scholar 

  14. Sietsema KE, Hiatt WR, Esler A, Adler S, Amato A, Brass EP (2002) Clinical and demographic predictors of exercise capacity in end-stage renal disease. Am J Kidney Dis 39:76–85

    Article  PubMed  Google Scholar 

  15. Miller BW, Cress CL, Johnson ME, Nichols DH, Schnitzler MA (2002) Exercise during hemodialysis decreases the use of antihypertensive medications. Am J Kidney Dis 39:828–833

    PubMed  Google Scholar 

  16. Zanconato S, Baraldi E, Montini G, Zacchello G, Zacchello F (1990) Exercise tolerance in end-stage renal disease. Child Nephrol Urol 10:26–31

    CAS  PubMed  Google Scholar 

  17. Sabath RJ (1999) Exercise evaluation of children with end-stage renal disease. Adv Ren Replace Ther 6:189–194

    CAS  PubMed  Google Scholar 

  18. Gledhill J, Rangel L, Garralda E (2000) Surviving chronic physical illness: psychosocial outcome in adult life. Arch Dis Child 83:104–110

    Article  CAS  PubMed  Google Scholar 

  19. Morton MJ, Reynolds JM, Garralda ME, Postlethwaite RJ, Roh D (1994) Psychiatric adjustment in end-stage renal disease: a follow up study of former paediatric patients. J Psychosom Res 38:293–303

    Article  CAS  PubMed  Google Scholar 

  20. Bruininks RH (1978) Bruininks-Oseretsky test of motor proficiency. Manual. American Guidance Service, Minnesota

  21. Cole B, Finch E, Gowland C, Mayo N (1994) Physical rehabilitation outcome measures. Canadian Physiotherapy Association, Toronto, pp 148–149

  22. Brinkhorst RA (1996) Dutch Heart Association, The Hague, The Netherlands

  23. Verrips EGH, Vogels TGC, Koopman HM, (1999) Measuring health-related quality of life in a child population. Eur J Public Health 9:188–193

    Google Scholar 

  24. Vogels TGC, Verrips EGH, Koopman HM (2000) TACQOL Manual. Center for Child Health and Pediatrics, Leiden

  25. Hulstijn-Dirkmaat GM, Jetten MLJ, Damhuis EHW, Essink ML (1992) Achterblijven motorische ontwikkeling van jonge kinderen met een ernstige nieraandoening. Ned Tijdschr Geneeskd 136:2281–2285

    CAS  PubMed  Google Scholar 

  26. Payne VG, Moorow JR (1993) Exercise and VO2 max in children: a meta-analysis. Res Q Exerc Sport 64:305–313

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Pediatric Physical Therapy and Exercise Physiology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, The Netherlands

    Rian M. Eijsermans & Paul J. Helders

  2. Department of Pediatric Nephrology, Wilhelmina Children’s Hospital, University Medical Center, Utrecht, The Netherlands

    Desiree G. Creemers & Cock H. Schröder

  3. Department of Pediatric Physical Therapy and Exercise Physiology, Wilhelmina Children’s Hospital, University Medical Center, Room KB 02.0560, P.O. Box 85090, 3508 AB Utrecht, The Netherlands

    Rian M. Eijsermans

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  1. Rian M. Eijsermans
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  2. Desiree G. Creemers
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  3. Paul J. Helders
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  4. Cock H. Schröder
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Correspondence to Rian M. Eijsermans.

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Eijsermans, R.M., Creemers, D.G., Helders, P.J. et al. Motor performance, exercise tolerance, and health-related quality of life in children on dialysis. Pediatr Nephrol 19, 1262–1266 (2004). https://doi.org/10.1007/s00467-004-1583-0

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  • DOI: https://doi.org/10.1007/s00467-004-1583-0

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