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Evidence for two different ICD-11 posttraumatic stress disorders in a community sample of adolescents and young adults

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European Archives of Psychiatry and Clinical Neuroscience Aims and scope Submit manuscript

Abstract

For the 11th revision of the International classification of diseases, a general category of posttraumatic stress disorders has been proposed with two distinct sibling disorders: posttraumatic stress disorder (PTSD) and complex PTSD (CPTSD). General population data are examined on evidence for these two disorders. Data were drawn from a 10-year prospective longitudinal, epidemiological study with a representative community sample (N = 3021, 14–24 years at baseline) in Germany. Mixture modelling on latent classes was conducted in a subset of all reported episodes with exposure to interpersonal traumas. Associations between class membership, symptom criteria, and other mental disorders were investigated. Four distinctly interpretable latent classes were found. Class 1 episodes (N = 181) typically included core PTSD symptoms associated with strong impairment (OR 11.68; 95 % CI 4.54–30.05). 18.3 % of these episodes matched the criteria of ICD-11 PTSD. Class 2 episodes (N = 78) had a high probability of PTSD core symptoms and disturbances in self-organization and were associated with strong impairment (OR 38.47; 95 % CI 15.77–93.86). Half of them (49.4 %) matched the proposed ICD-11 criteria of CPTSD. Class 3 (N = 79) was typically characterized by episodes with disturbances in self-organization but a low probability of PTSD core symptoms and impairment. Class 4 (N = 633) was related to a relatively low probability of symptom reports. Membership in class 2 was associated with lower educational attainment, a lower social class, and more other mental disorders. Findings support the ICD-11 proposal to differentiate between PTSD and CPTSD. Further studies should extend exploration to other types of traumatic events in samples covering the full age range.

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References

  1. Maercker A, Brewin CR, Bryant RA, Cloitre M, Reed GM, van Ommeren M, Humayun A, Jones LM, Kagee A, Llosa AE, Rousseau C, Somasundaram DJ, Souza R, Suzuki Y, Weissbecker I, Wessely SC, First MB, Saxena S (2013) Proposals for mental disorders specifically associated with stress in the ICD-11. Lancet 381:1683–1685

    Article  PubMed  Google Scholar 

  2. Maercker A, Brewin CR, Bryant RA, Cloitre M, van Ommeren M, Jones LM, Humayan A, Kagee A, Llosa AE, Rousseau C, Somasundaram DJ, Souza R, Suzuki Y, Weissbecker I, Wessely SC, First MB, Reed GM (2013) Diagnosis and classification of disorders specifically associated with stress: new proposals for ICD-11. World Psychiatry 12:198–206

    Article  PubMed  PubMed Central  Google Scholar 

  3. Cloitre M, Garvert DW, Brewin CR, Bryant RA, Maercker A (2013) Evidence for proposed ICD-11 PTSD and complex PTSD: a latent profile analysis. Eur J Psychotraumatol. doi:10.3402/ejpt.v4i0.20706

    Google Scholar 

  4. Dalenberg CJ, Glaser D, Alhassoon OM (2012) Statistical support for subtypes in posttraumatic stress disorder: the how and why of subtype analysis. Depress Anxiety 29:671–678

    Article  PubMed  Google Scholar 

  5. Lanius RA, Vermetten E, Loewenstein RJ, Brand B, Schmahl C, Bremner JD, Spiegel D (2010) Emotion modulation in PTSD: clinical and neurobiological evidence for a dissociative subtype. Am J Psychiatry 167:640–647

    Article  PubMed  PubMed Central  Google Scholar 

  6. Andrews L, Joseph S, Shevlin M, Troop N (2006) Confirmatory factor analysis of posttraumatic stress symptoms in emergency personnel: an examination of seven alternative models. Pers Individ Differ 41:213–224

    Article  Google Scholar 

  7. Pietrzak RH, Tsai J, Harpaz-Rotem I, Whealin JM, Southwick SM (2012) Support for a novel five-factor model of posttraumatic stress symptoms in three independent samples of Iraq/Afghanistan veterans: a confirmatory factor analytic study. J Psychiatry Res 46:317–322

    Article  Google Scholar 

  8. American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders: DSM-5, 5th edn. American Psychiatric Publishing, Arlington

    Google Scholar 

  9. Asmundson GJ, Stapleton JA, Taylor S (2004) Are avoidance and numbing distinct PTSD symptom clusters? J Trauma Stress 17:467–475

    Article  PubMed  Google Scholar 

  10. Friedman MJ, Resick PA, Bryant RA, Strain J, Horowitz M, Spiegel D (2011) Classification of trauma and stressor-related disorders in DSM-5. Depress Anxiety 28:737–749

    Article  PubMed  Google Scholar 

  11. Friedman MJ (2013) Finalizing PTSD in DSM-5: getting here from there and where to go next. J Trauma Stress 26:548–556

    Article  PubMed  Google Scholar 

  12. Rademaker AR, Van Minnen A, Ebberink F, Van Zuiden M, Hagenaars MA, Geuze E (2012) Symptom structure of PTSD: support for a hierarchical model separating core PTSD symptoms from dysphoria. Eur J Psychotraumatol. doi:10.3402/ejpt.v3i0.17580

    Google Scholar 

  13. Herman JL (1992) Trauma and recovery: the aftermath of violence from domestic violence to political terrorism. Guilford Press, New York

    Google Scholar 

  14. American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders (4th ed., text rev.). Author: Washington, DC

  15. Roth S, Newman E, Pelcovitz D, Van der Kolk B, Mandel FS (1997) Complex PTSD in victims exposed to sexual and physical abuse: results from the DSM-IV field trial for posttraumatic stress disorder. J Trauma Stress 10:539–555

    CAS  PubMed  Google Scholar 

  16. Cloitre M, Courtois CC, Charuvastra A, Carapezza R, Stolbach BC, Green BL (2011) Treatment of complex PTSD: results of the ISTSS expert clinician survey on best practices. J Trauma Stress 24:616–627

    Article  Google Scholar 

  17. Dorahy MJ, Corry M, Shannon M, Macsherry A, Hamilton G, McRobert G, Elder R, Hanna D (2009) Complex PTSD, interpersonal trauma and relational consequences: findings from a treatment-receiving Northern Irish sample. J Affect Disord 112:71–80

    Article  PubMed  Google Scholar 

  18. Dorrepaal E, Thomaes K, Smit JH, Hoogendoorn A, Veltman DJ, van Balkom AJ, Draijer N (2012) Clinical phenomenology of childhood abuse-related complex PTSD in a population of female patients: patterns of personality disturbance. J Trauma Dissociation 13:271–290

    Article  PubMed  Google Scholar 

  19. Resick PA, Bovin MJ, Calloway AL, Dick AM, King MW, Mitchell KS, Suvak MK, Wells SY, Stirman SW, Wolf EJ (2012) A critical evaluation of the complex PTSD literature: implications for DSM-5. J Trauma Stress 25:241–251

    Article  PubMed  Google Scholar 

  20. Lieb R, Isensee B, von Sydow K, Wittchen HU (2000) The early developmental stages of psychopathology study (EDSP): a methodological update. Eur Addict Res 6:170–182

    Article  CAS  PubMed  Google Scholar 

  21. Wittchen HU, Perkonigg A, Lachner G, Nelson CB (1998) The early developmental stages of psychopathology study (EDSP)—objectives and design. Eur Addict Res 4:18–27

    Article  CAS  PubMed  Google Scholar 

  22. Wittchen HU, Pfister H (1997) DIA-X-Interviews: manual für Screening-Verfahren und Interview; Interviewheft Längsschnittuntersuchung [DIA-X-Lifetime]; Ergänzungsheft [DIA-X Lifetime]; Interviewheft Querschnittuntersuchung [DIA-X 12 Monate]; Ergänzungsheft [DIA-X 12 Monate]; PC-Programm zur Durchführung des Interviews (Längs- und Querschnittuntersuchung); Auswertungsprogramm. Swets and Zeitlinger, Frankfurt

  23. Reed V, Gander F, Pfister H, Steiger A, Sonntag H, Trenkwalder C, Sonntag A, Hundt W, Wittchen HU (1998) To what degree the composite international diagnostic interview (CIDI) correctly identifies DSM-IV disorders? testing validity issues in a clinical sample. Int J Methods Psychiatry Res 7:142–155

    Article  Google Scholar 

  24. Wittchen HU, Lachner G, Wunderlich U, Pfister H (1998) Test–retest reliability of the computerized DSM-IV-version of the munich-composite international diagnostic interview (MCIDI). Soc Psychiatr Psychiatric Epidemiol 33:568–578

    Article  CAS  Google Scholar 

  25. Watson D (2005) Rethinking the mood and anxiety disorders: a quantitative hierarchical model for DSM-V. J Abnorm Psychol 114:522–536

    Article  PubMed  Google Scholar 

  26. Perkonigg A, Kessler RC, Storz S, Wittchen HU (2000) Traumatic events and posttraumatic stress disorder in the community: prevalence, risk factors and comorbidity. Acta Psychiatry Scand 101:46–59

    Article  CAS  Google Scholar 

  27. Derogatis LR (1986) SCL-90-R. Self-report symptom inventory. In: Collegium internationale psychiatriae scalaru M (eds) Internationale Skalen für Psychiatrie. Beltz, Weinheim

  28. Franke GH (2000) Symptom checkliste von L. R. Derogatis Manual. Beltz Test Gmbh, Göttingen

    Google Scholar 

  29. Royall RM (1986) The prediction approach to robust variance estimation in two-stage cluster sampling. J Am Stat Assoc 81:119–123

    Article  Google Scholar 

  30. Schwarz G (1978) Estimating the dimension of a model. Ann Stat 6:461–464

    Article  Google Scholar 

  31. Sclove S (1987) Application of model-selection criteria to some problems in multivariate analysis. Psychometrika 52:333–343

    Article  Google Scholar 

  32. Akaike H (1987) Factor analysis and AIC. Psychometrika 52:317–332

    Article  Google Scholar 

  33. Lo Y, Mendell NR, Rubin DB (2001) Testing the number of components in a normal mixture. Biometrika 88:767–778

    Article  Google Scholar 

  34. Asparouhov T, Muthén B (2014) Auxiliary variables in mixture modeling: three-step approaches using mplus. Structural equation modeling. Multidiscip J 21:1–13

    Google Scholar 

  35. Elklit A, Hyland P, Shevlin M (2014) Evidence of symptom profiles consistent with posttraumatic stress disorder and complex posttraumatic stress disorder in different trauma samples. Eur J Psychotraumatol. doi:10.3402/ejpt.v5.24221

    Google Scholar 

  36. Knefel M, Garvert DW, Cloitre M, Lueger-Schuster B (2015) Update to an evaluation of ICD-11 PTSD and complex PTSD criteria in a sample of adult survivors of childhood institutional abuse by Knefel & Lueger-Schuster (2013): a latent profile analysis. Eur J Psychotraumatol. doi:10.3402/ejpt.v6.25290

    PubMed  PubMed Central  Google Scholar 

  37. Cloitre M, Garvert DW, Weiss B, Carlson E, Bryant RA (2014) Distinguishing PTSD, complex PTSD, and borderline personality disorder: a latent class analysis. Eur J Psychotraumatol. doi:10.3402/ejpt.v5.2509

    PubMed  PubMed Central  Google Scholar 

  38. Reed GM (2010) Toward ICD-11: improving the clinical utility of WHO’s international classification of mental disorders. Prof Psychol Res Pract 41:457–464

    Article  Google Scholar 

  39. Keeley JW, Reed GM, Roberts MC, Evans SC, Robles R, Matsumoto C, Brewin CR, Cloitre M, Perkonigg A, Rousseau C, Gureje O, Lovell AM, Sharan P, Maercker A Disorders specifically associated with stress: a case-controlled field study for ICD-11 mental and behavioural disorders. Inter J Clinic Health Psychol (in press)

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Acknowledgments

This work is part of the early developmental stages of psychopathology (EDSP) Study. The EDSP Study has been funded by the German Federal Ministry of Education and Research (BMBF) project no. 01EB9405/6, 01 EB 9901/6, EB01016200, 01EB0140, and 01EB0440. Part of the field work and analyses were also additionally supported by grants of the Deutsche Forschungsgemeinschaft (DFG) LA1148/1-1, WI2246/1-1, WI 709/7-1, and WI 709/8-1. Principal investigators of the EDSP are Dr. Hans-Ulrich Wittchen and Dr. Roselind Lieb. Core staff members of the EDSP group are: Dr. Kirsten von Sydow, Dr. Gabriele Lachner, Dr. Axel Perkonigg, Dr. Peter Schuster, Dr. Michael Höfler, Dipl.-Psych. Holger Sonntag, Dipl.-Psych. Tanja Brückl, Dipl.-Psych. Elzbieta Garczynski, Dr. Barbara Isensee, Dipl.-Psych. Agnes Nocon, Dr. Chris Nelson, Dipl.-Inf. Hildegard Pfister, Dr. Victoria Reed, Dipl.-Soz. Barbara Spiegel, Dr. Andrea Schreier, Dr. Ursula Wunderlich, Dr. Petra Zimmermann, Dr. Katja Beesdo-Baum, Dr. Antje Bittner, Dr. Silke Behrendt, and Dr. Susanne Knappe. Scientific advisors are Dr. Jules Angst (Zurich), Dr. Jürgen Margraf (Basel), Dr. Günther Esser (Potsdam), Dr. Kathleen Merikangas (NIMH, Bethesda), Dr. Ron Kessler (Harvard, Boston), and Dr. Jim van Os (Maastricht).

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Correspondence to Axel Perkonigg.

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Perkonigg, A., Höfler, M., Cloitre, M. et al. Evidence for two different ICD-11 posttraumatic stress disorders in a community sample of adolescents and young adults. Eur Arch Psychiatry Clin Neurosci 266, 317–328 (2016). https://doi.org/10.1007/s00406-015-0639-4

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