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Quality of life in head and neck cancers patients: predictive factors, functional and psychosocial outcome

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European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

The principal endpoints in head and neck cancer are survival with improvement of quality of life (QoL) in cancer patients. Patients treated for head and neck cancer suffer from a number of symptom domains: physical symptoms linked to diet and feeding, communication disorders, pain and their general state of health; psychological symptoms including depression, irritability, loss of self-esteem (occasionally feelings of shame), and social symptoms including relationship difficulties with partner (sexual disorders) or with other family members, loss of work, reduction in salary, and sense of uselessness, resulting in a negative impact on their daily life. At present, most tools only partially evaluate patient QoL, concentrating on the global impact of disease and its treatment on patients’ physical and psychological condition. The “sociability” of individual patients is rarely evaluated, and the development of qualitative studies in this domain will enable improved understanding of the social factors involved in each patient’s adaptability to disease, its treatment and after-effects.

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References

  1. De Graeff A, de Leeuw JR, Ros WJ, Hordijk GJ, Blijham GH, Winnubust JA (2000) Long-term quality of life of patients with head and neck cancer. Laryngoscope 110:98–106

    Article  PubMed  Google Scholar 

  2. Allison PJ, Locker D, Wood-Dauphin S, Black M, Feine JS (1998) Correlates of health-related quality of life in upper aerodigestive tract cancer patients. Qual Life Res 7:713–722

    Article  PubMed  CAS  Google Scholar 

  3. Lee-PrestonV, Steen IN, Dear A, Kelly CG, Welch AR, Meikle D, Stafford FW, Wilson JA (2004) Optimizing the assessment of quality of life after laryngeal cancer treatment. J Laryngol Otol 118:432–448

    Article  Google Scholar 

  4. Taylor JC, Terrel JE, Ronis DL, Fowler KE, Bishop C, Lambert MT, Myers LL, Duffy SA (2004) Disability in patients with head, neck cancer. Arch Otolaryngol Head Neck Surg 130:764–769

    Article  PubMed  Google Scholar 

  5. Woodard TD, Oplatek A, Petruzelli GJ (2007) Life after total laryngectomy. Arch Otolaryngol Hea Neck Surg 133:526–532

    Article  Google Scholar 

  6. Duffy SA, Terrel JE, Valenstein M, Ronis DL, Copeland LA, Connors M (2002) Effect of smoking, alcohol and depression on the quality of life of head and neck cancer patients. Gen Hosp Psychiatry 24:140–147

    Article  PubMed  Google Scholar 

  7. Allison PJ (2002) Alcohol consumption is associated with improved health-related quality of life in head and neck cancer patients. Oral Oncol 38:81–86

    Article  PubMed  CAS  Google Scholar 

  8. Vartanian JG, Carvahlo AL, Toyota J, Kowalski ISG, Kowalski LP (2006) Socioeconomic effect of and risk factors for disability in long-term survivors of head and neck cancer. Arch Otolaryngol Head Neck Surg 132:32–35

    Article  PubMed  Google Scholar 

  9. Long SA, D’Antonio LL, Robinson EB, Zimmerman G, Petti G, Chonkich G (1996) Factors related to quality of life and functional status in 50 patients with head and neck cancer. Laryngoscope 106:1084–1088

    Article  PubMed  CAS  Google Scholar 

  10. Fang FM, Chiu HC, Kuo WR, Wang CL, Leung SW, Chen HC et al (2002) Health-related quality of life for nasopharyngeal carcinoma patients with cancer-free survival after treatment. Int J Radiat Oncol Biol Phys 53:959–968

    PubMed  Google Scholar 

  11. Terrell JE, Ronis DL, Fowler KE, Bradford CR, Chepea DB, Prince ME, Teknos TN, Wolf GT, Duffy SA (2004) Clinical predictors of quality of life in patients with head and neck cancer. Arch Otolaryngol Head Neck Surg 30:401–408

    Article  Google Scholar 

  12. Morton RP (2003) Studies in the quality of life of head and neck cancer patients: results of a two-year longitudinal study and a comparative cross-sectional cross-cultural survey. Laryngoscope 113:1091–1103

    Article  PubMed  Google Scholar 

  13. Hammerlid E, Silander E, Hornestam L, Sullivan M (2001) Health-related quality of life three years after diagnosis of head and neck cancer a longitudinal study. Head Neck 23:113–125

    Article  PubMed  CAS  Google Scholar 

  14. Bartelink H, Schellens JH, Verheij M (2002) The combined use of radiotherapy and chemotherapy in the treatment of solid tumours. Eur J Cancer 38:216–222

    Article  PubMed  CAS  Google Scholar 

  15. List M, Siston A, Haraf D, Schumm P, Kies P, Stenson K et al (1999) Quality of life and performance in advanced head and neck cancer patients on concomitant chemoradiotherapy: a prospective examination. J Clin Oncol 17:1020–1028

    PubMed  CAS  Google Scholar 

  16. Allal AS, Nicoucar K, Mach N, Dulguerov P (2003) Quality of life in patients with oropharynx carcinomas: assessment after accelerated radiotherapy with or without chemotherapy versus radical surgery and postoperative radiotherapy. Head Neck 25:833–840

    Article  PubMed  Google Scholar 

  17. Deleyiannis FWB, Weymuller EA Jr, Coltrera MD, Futran N (1999) Quality of life after laryngectomy: are functional disabilities important? Head Neck 21:319–324

    Article  PubMed  CAS  Google Scholar 

  18. Scrimger R, Kanji A, Parliament M, Warkentin H, Field C, Jha N, Hanson J (2007) Correlation between saliva production and quality of life measurements in head and neck cancer patients treated with intensity-modulated radiotherapy. Am J Clin Oncol 30:271–277

    Article  PubMed  Google Scholar 

  19. Abendstein H, Nordgren M, Boysen M, Jannert M, Silander E, Ahlner-Elmqvist M, Hammerlid E, Bjordal K (2005) Quality of life and head and neck cancer: a 5-year prospective study. Laryngoscope 115:2183–2192

    Article  PubMed  Google Scholar 

  20. Magné N, Marcy PY, Chamorey E, Guardiola E, Pivot X, Schneider M, Demard F, Bensadoun RJ (2001) Concomitant twice-a-day radiotherapy and chemotherapy in unresectable head and neck cancer patients: a long-term quality of life analysis. Head Neck 23:678–682

    Article  PubMed  Google Scholar 

  21. Mehanna HM, Morton RP (2006) Does quality of life predict long term survival in patients with head and neck cancer? Arch Otolaryngol Head Neck Surg 132:27–31

    Article  PubMed  Google Scholar 

  22. Terrell JE, Nanavati K, Esclamado RM, Bradford CR, Wolf GT (1999) Health impact of head and neck cancer. Otolaryngol Head Neck Surg 120:852–859

    Article  PubMed  CAS  Google Scholar 

  23. Tschudi D, Stoeckli S, Schmid S (2003) Quality of life after different treatment modalities for carcinoma of the oropharynx. Laryngoscope 113:1949–1954

    Article  PubMed  Google Scholar 

  24. List MA, Rutherford JL, Stracks J, Pauloski BR, Logemann JA, Lundy D, Sullivan P, Goodwin W, Kies M, Vokes EE (2004) Prioritizing treatment outcomes: head and neck cancer patients versus nonpatients. Head Neck 26:163–170

    Article  PubMed  Google Scholar 

  25. Morton RP (1995) Evolution of quality of life assessment in head and neck cancer. J Laryngol Otol 109:1029–1035

    Article  PubMed  CAS  Google Scholar 

  26. Ferrer Ramirez MJ, Ferriol EE, Doménech FG, Llatas MC, Suarez-Varela MM, Martinez RL (2003) Psychosocial adjustment in patient surgically treated for laryngeal cancer. Otolayngol Head Neck Surg 129:92–97

    Article  Google Scholar 

  27. Babin E, Joly F, Vadillo M, Dehesdin D (2005) Qualité de vie en cancérologie. Application aux cancers des voies aéro-digestives supérieures. Ann Otolaryngol Chir Cervicofac 122:134–141

    PubMed  CAS  Google Scholar 

  28. Bjordal K, Kaasa S (1995) Psychological distress in head and neck cancer patients 7–11 years after curative treatment. Br J Cancer 71:592–597

    PubMed  CAS  Google Scholar 

  29. D’Antonio LL, Long SA, Zimmerman GJ, Peterman AH, Petti GH, Chonkich GD (1998) Relationship between quality of life and depression in patients with head and neck cancer. Laryngoscope 108:806–811

    Article  PubMed  CAS  Google Scholar 

  30. Nahum AM, Golden J (1963) Psychological problems of laryngectomy. JAMA 28:70–80

    Google Scholar 

  31. Babin E (2002) La vie après la laryngectomie totale. Rev Laryngol Otol Rhinol 122:303–309

    Google Scholar 

  32. Armstrong E, Isman K, Dooley P, Brine D, Riley N, Dentice R, King S, Khanbhai F (2001) An investigation into the quality of life of individuals after laryngectomy. Head Neck 23:16–24

    Article  CAS  Google Scholar 

  33. Herranz J, Gavilan J (1999) Psychosocial adjustment after laryngeal cancer surgery. Ann Otol Rhinol Laryngol 108:990–997

    PubMed  CAS  Google Scholar 

  34. Kessler RC, Greenberg PE, Mickelson KD, Meneades LM, Wang PS (2001) The effects of chronic medical conditions on work loss and work cutback. J Occup Environ Med 43:218–225

    Article  PubMed  CAS  Google Scholar 

  35. Pusic A, Liui JC, Chen CM, Cano S, Davidge K, Klassen A, Branski R, Patel S, Kraus D, Cordeiro PG (2007) A systematic review of patient-reported outcome measures in head and neck cancer surgery. Otolayngol Head Neck Surg 136:525–535

    Article  Google Scholar 

  36. Coates A, Gebski JC, Signorini D, Murray P, McNeil D, Byrne M (1992) Prognostic value of quality-of-life scores during chemotherapy for advanced breast cancer. J Clin Oncol 10:1833–1838

    PubMed  CAS  Google Scholar 

  37. Ruckdeschel JC, Piantadosi S (1991) The Lung Cancer Study Group. Quality of life assessment in lung surgery for bronchogenic carcinoma. J Theor Surg 6:201–205

    Google Scholar 

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Babin, E., Sigston, E., Hitier, M. et al. Quality of life in head and neck cancers patients: predictive factors, functional and psychosocial outcome. Eur Arch Otorhinolaryngol 265, 265–270 (2008). https://doi.org/10.1007/s00405-007-0561-0

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  • DOI: https://doi.org/10.1007/s00405-007-0561-0

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