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The pediatric Chiari I malformation: a review

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Abstract

Background

Both the diagnosis and treatment regimens for the Chiari I malformation (CIM) are varied and controversial. The present paper analyzes the literature regarding this form of hindbrain herniation in regard to definition, anatomy, pathobiology, symptoms, findings, treatment, and outcomes.

Discussions

Appropriate literature germane to the CIM is reviewed and discussed. There is variation in the reported anatomy, outcome, and treatment for children with CIM. Based on the literature, most patients have preoperative symptoms or findings (e.g., syringomyelia) improve no matter what surgical technique is utilized. However, standardized treatment paradigms based on randomized controlled studies are still necessary to elucidate the optimal selection and treatment criteria.

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Authors and Affiliations

  1. Section of Pediatric Neurosurgery, Children’s Hospital, University of Alabama at Birmingham, 1600 7th Avenue South ACC 400, Birmingham, AL, 35233, USA

    R. Shane Tubbs & W. Jerry Oakes

  2. Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL, USA

    R. Shane Tubbs & W. Jerry Oakes

  3. University of Alabama School of Medicine, Birmingham, AL, USA

    Michael J. Lyerly

  4. Department of Anatomical Sciences, St. George’s University, Grenada, Boston, MA, USA

    Marios Loukas

  5. Department of Education and Development, Harvard Medical School, Boston, MA, USA

    Marios Loukas

  6. Tuberculosis and Lung Disease Research Center, Tabriz Medical University, Tabriz, Iran

    Mohammadali M. Shoja

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  1. R. Shane Tubbs
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Correspondence to R. Shane Tubbs.

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Tubbs, R.S., Lyerly, M.J., Loukas, M. et al. The pediatric Chiari I malformation: a review. Childs Nerv Syst 23, 1239–1250 (2007). https://doi.org/10.1007/s00381-007-0428-0

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  • DOI: https://doi.org/10.1007/s00381-007-0428-0

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