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Long-term follow-up after cystectomy for bladder pain syndrome: pain status, sexual function and quality of life

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Abstract

Purpose

To assess the long-term complications, pain status, sexual function and quality of life after cystectomy for bladder pain syndrome (BPS).

Methods

We retrospectively reviewed functional variables for 35 patients (34 women/1 man, 67 ± 9 years old) who underwent cystectomy due to BPS since 1993 in our department. Cystectomy was offered to patients with BPS refractory to conservative treatments. Six cystectomies with ileal conduit (17.1%) and 29 supratrigonal cystectomies with enterocystoplasty (82.9%) were performed. Prospectively, patients completed questionnaires on pain [BPIC-SS, visual analogue scale (VAS) for pain], health-related quality of life (EQ-5D) and sexual function (FSFI; 2–36), rated satisfaction with surgery (0–10) and reported whether they would undergo the same surgery again.

Results

Mean follow-up was 107 ± 83 months. In two (5.7%) patients, pain persisted and in one patient (2.8%) pain recurred after 20 months. Significant improvements in daytime and nighttime frequency and bladder capacity were observed postoperatively. 21 patients completed questionnaires. Mean BPIC-SS was 7.5 ± 8.4, mean VAS score 2.5 ± 2.8. 14 (66.7%) patients reported no problems related to pain on the EQ-5D, similar to our regional reference population. 13 (61.9%) patients had sexual intercourse after surgery, ten of them without pain. Mean FSFI score was 9.5 ± 9. Satisfaction with surgery was 8.8 ± 1.7 and 20 (95.2%) patients would undergo the same surgery again.

Conclusion

Pain persistence or recurrence after cystectomy for BPS is infrequent. Quality of life related to pain is similar to that in the general population and patients can resume sexual activity without pain.

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Funding

This study was not funded.

Author information

Authors and Affiliations

  1. Female and Functional Urology Department, Fundació Puigvert, C/Cartagena 340-350, 08025, Barcelona, Spain

    Laura Mateu Arrom, Cristina Gutiérrez Ruiz, Olga Mayordomo Ferrer, Virginia Martínez Barea & Carlos Errando Smet

  2. Chief of the Urology Department, Fundació Puigvert, Barcelona, Spain

    Joan Palou Redorta

Authors
  1. Laura Mateu Arrom
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  2. Cristina Gutiérrez Ruiz
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  3. Olga Mayordomo Ferrer
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  4. Virginia Martínez Barea
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  5. Joan Palou Redorta
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  6. Carlos Errando Smet
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Contributions

LM: project development, data collection, data analysis, manuscript writing. CG: project development, manuscript writing. OM: data collection. VM: manuscript writing. JP: manuscript editing. CE: project development, data analysis, manuscript writing and editing.

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Correspondence to Laura Mateu Arrom.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Mateu Arrom, L., Gutiérrez Ruiz, C., Mayordomo Ferrer, O. et al. Long-term follow-up after cystectomy for bladder pain syndrome: pain status, sexual function and quality of life. World J Urol 37, 1597–1603 (2019). https://doi.org/10.1007/s00345-018-2554-6

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  • DOI: https://doi.org/10.1007/s00345-018-2554-6

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