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Seronegative Lyme arthritis

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Abstract

We present a 10-year-old girl who had been diagnosed with juvenile idiopathic arthritis 5 years before and who experienced a flare of arthritis affecting one knee while she was off medication for almost 3 years. Seronegative Lyme arthritis had to be diagnosed based on the detection of Borrelia burgdorferi DNA in synovial fluid. No humoral immune response to Borrelia burgdorferi was detectable before, at the time of diagnosis and up to 3 years later.

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Fig. 1

Abbreviations

NSAID:

Nonsteroidal anti-inflammatory drugs

IAS:

Intraarticular corticoid injections

JIA:

Juvenile idiopathic arthritis

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Authors and Affiliations

  1. Children’s hospital, Section of Pediatric Rheumatology, Immunology and Infectious diseases, University of Wuerzburg, Josef-Schneider-Str. 2, 97090, Wuerzburg, Germany

    A. Holl-Wieden & H. J. Girschick

  2. Institute of Microbiology and Hygiene, University of Würzburg, Wuerzburg, Germany

    S. Suerbaum

Authors
  1. A. Holl-Wieden
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  2. S. Suerbaum
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  3. H. J. Girschick
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Corresponding author

Correspondence to H. J. Girschick.

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Holl-Wieden, A., Suerbaum, S. & Girschick, H.J. Seronegative Lyme arthritis. Rheumatol Int 27, 1091–1093 (2007). https://doi.org/10.1007/s00296-007-0333-6

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  • DOI: https://doi.org/10.1007/s00296-007-0333-6

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