Skip to main content
SpringerLink
Log in

Diffuse bone metastases on 68Ga-PSMA PET-CT in a patient with prostate cancer and normal bone scan

  • Image of the Month
  • Published:
European Journal of Nuclear Medicine and Molecular Imaging Aims and scope Submit manuscript

Abstract

A 75-year-old patient was diagnosed with a Gleason 9 prostate carcinoma. His PSA level was 50.4 ng/ml. Routine bone scintigraphy was negative for metastasis (a). Due to the high tumour grading and relatively high PSA level, 68Ga-PSMA PET-CT was ordered to rule out distant metastases. This scan showed numerous skeletal lesions with high tracer accumulation as sign of diffuse osseous metastases (b). On low-dose CT there were no signs of sclerosis (c). 68Ga-PSMA PET-CT also showed high uptake in the prostate and in para-iliac and para-aortal lymph nodes, without lymph node enlargement. No bone biopsy was obtained to confirm the metastases. Due to this result, the treatment plan was changed to systemic therapy, instead of local therapy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Reference

  1. Afshar Oromieh A, Avtzi E, Giesel FL, HollandLetz T, Linhart HG, Eder M, et al. The diagnostic value of PET/CT imaging with the (68)Ga-labelled PSMA ligand HBED-CC in the diagnosis of recurrent prostate cancer. Eur J Nucl Med Mol Imaging. 2015;42:197–209.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Nuclear Medicine, Sint Antonius Ziekenhuis, Nieuwegein, The Netherlands

    J. Lavalaye & P. Kaldeway

  2. Department of Urology, Sint Antonius Ziekenhuis, Nieuwegein, The Netherlands

    H. H. E. van Melick

Authors
  1. J. Lavalaye
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. Kaldeway
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. H. E. van Melick
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to J. Lavalaye.

Ethics declarations

Funding

None.

Conflicts of interest

The authors declare they do not have any conflicts of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lavalaye, J., Kaldeway, P. & van Melick, H.H.E. Diffuse bone metastases on 68Ga-PSMA PET-CT in a patient with prostate cancer and normal bone scan. Eur J Nucl Med Mol Imaging 43, 1563–1564 (2016). https://doi.org/10.1007/s00259-016-3398-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00259-016-3398-1

Keywords

Search

Navigation