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Prevalence of Associated Cardiovascular Abnormalities in 500 Patients With Aortic Coarctation Referred for Cardiovascular Magnetic Resonance Imaging to a Tertiary Center

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Abstract

Coarctation of the aorta (CoA) is a common congenital defect whose overall incidence is 5–8% of all congenital cardiac anomalies. Associated cardiac anomalies have been well described in previous studies examining specific subgroups of CoA patients, particularly infants and necropsy specimens. The majority of studies, conducted from the 1970s to 1980s, excluded older children, adolescents, and adults. Given the advent of improved surgical and interventional techniques, many CoA patients are surviving into adulthood. This study examined a population of 500 CoA patients in the authors’ cardiovascular magnetic resonance imaging (MRI) database involving a population of CoA survivors 5–79 years of age. This was to give a new perspective on the prevalence of associated cardiovascular abnormalities including the bicuspid aortic valve, arch hypoplasia, intracardiac shunts, and subaortic stenosis. These associated abnormalities are less prevalent than in previous studies, reflecting a milder spectrum of CoA. Cardiovascular MRI with its multiplanar imaging capabilities and lack of ionizing radiation is safe and suitable for evaluation and follow-up assessment of CoA patients. Evaluation of CoA by MRI should not be confined to the arch, but should include the heart and mediastinal vessels to assess for the presence and severity of any expected or unexpected associated anomalies.

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Acknowledgments

Lynette L. S. Teo was supported by a grant from the Health Manpower Development Plan (National Healthcare Group, Ministry of Health, Singapore). Sonya V. Babu-Narayan was supported by the British Heart Foundation. This project was supported by the NIHR Cardiovascular Biomedical Research Unit of Royal Brompton and Harefield NHS Foundation Trust and Imperial College London.

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Authors and Affiliations

  1. Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore

    Lynette L. S. Teo

  2. Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK

    Tim Cannell, Sonya V. Babu-Narayan, Marina Hughes & Raad H. Mohiaddin

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  1. Lynette L. S. Teo
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  2. Tim Cannell
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  3. Sonya V. Babu-Narayan
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  4. Marina Hughes
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  5. Raad H. Mohiaddin
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Correspondence to Raad H. Mohiaddin.

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Teo, L.L.S., Cannell, T., Babu-Narayan, S.V. et al. Prevalence of Associated Cardiovascular Abnormalities in 500 Patients With Aortic Coarctation Referred for Cardiovascular Magnetic Resonance Imaging to a Tertiary Center. Pediatr Cardiol 32, 1120–1127 (2011). https://doi.org/10.1007/s00246-011-9981-0

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  • DOI: https://doi.org/10.1007/s00246-011-9981-0

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