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PF4-heparin antibodies during ECMO: incidence, course, and outcomes

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References

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Acknowledgments

We thank Prof. I. Elalamy for performing the SRAs for the study.

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Authors and Affiliations

  1. Cardiothoracic Intensive Care Unit, Service de Réanimation Adulte, Hôpital Marie Lannelongue, 133 Avenue de la Résistance, 92350, Le Plessis Robinson, France

    Florent Laverdure, Talna Kortchinsky, Saïda Rezaiguïa-Delclaux, Audrey Imbert & François Stéphan

  2. Hemostasis Laboratory, Hôpital Marie Lannelongue, 133 Avenue de la Résistance, 92350, Le Plessis Robinson, France

    Virginie Louvain-Quintard

Authors
  1. Florent Laverdure
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  2. Virginie Louvain-Quintard
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  3. Talna Kortchinsky
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  4. Saïda Rezaiguïa-Delclaux
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  5. Audrey Imbert
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  6. François Stéphan
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Corresponding author

Correspondence to François Stéphan.

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Conflicts of interest

F Laverdure, V Louvain-Quintard, T Kortchinsky, S Rezaiguïa-Delclaux, A Imbert, and F Stéphan have no conflicts of interest to disclose.

Role of the sponsors

The study was funded solely by institutional and departmental sources, which had no role in developing the research or manuscript.

Electronic supplementary material

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134_2016_4262_MOESM1_ESM.jpg

Patient flow chart. OD optical density, PAT platelet aggregation test, PF4-H anti-platelet factor 4 antibodies, HIT heparin-induced thrombocytopenia. *No suggestive clinical presentation, retrospective results (JPEG 43 kb)

134_2016_4262_MOESM2_ESM.jpg

Platelet counts over time in patients with and without PF4-H antibodies. No significant difference was shown between patients with and without PF4-H (ANOVA test). Black triangles patients without PF4-H. White squares patients with PF4-H (JPEG 21 kb)

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Laverdure, F., Louvain-Quintard, V., Kortchinsky, T. et al. PF4-heparin antibodies during ECMO: incidence, course, and outcomes. Intensive Care Med 42, 1082–1083 (2016). https://doi.org/10.1007/s00134-016-4262-2

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  • DOI: https://doi.org/10.1007/s00134-016-4262-2

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