Skip to main content

Advertisement

Log in

Consensus Meeting on Microdialysis in Neurointensive Care

  • Consensus Report
  • Published:
Intensive Care Medicine Aims and scope Submit manuscript

Abstract

Background

Microdialysis is used in many European neurointensive care units to monitor brain chemistry in patients suffering subarachnoid hemorrhage (SAH) or traumatic brain injury (TBI).

Discussion

We present a consensus agreement achieved at a meeting in Stockholm by a group of experienced users of microdialysis in neurointensive care, defining the use of microdialysis, placement of catheters, unreliable values, chemical markers, and clinical use in SAH and in TBI.

Conclusions

As microdialysis is maturing into a clinically useful technique for early detection of cerebral ischemia and secondary brain damage, there is a need to following such definition regarding when and how to use microdialysis after SAH and TBI.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Ungerstedt U, Pycock C (1974) Functional correlates of dopamine neurotransmission. Bull Schweiz Akad Med Wiss 30:44–55

    CAS  PubMed  Google Scholar 

  2. Ungerstedt U (1991) Microdialysis—principles and applications for studies in animals and man. J Intern Med 230:365–3673

    CAS  PubMed  Google Scholar 

  3. Hutchinson P (2002) Third International Satellite Conference on Neuro-Chemical Monitoring: proposed guidelines for neuro-chemical monitoring. Acta Neurochir (Wien) 81:341–342

    Google Scholar 

  4. Hutchinson PJ, O’Connell MT, Al-Rawi PG, Maskell LB, Kett-White R, Gupta AK, Richards HK, Hutchinson DB, Kirkpatrick PJ, Pickard JD (2000) Clinical cerebral microdialysis: a methodological study. J Neurosurg 93:37–43

    CAS  Google Scholar 

  5. Chesnut R (1995) Secondary brain insults after head injury: clinical perspectives. New Horiz 3:366–375

    CAS  PubMed  Google Scholar 

  6. Maas AI, Dearden M, Teasdale GM, Braakman R, Cohadon F, Iannotti F, Karimi A, Lapierre F, Murray G, Ohman J, Persson L, Servadei F, Stocchetti N. Unterberg A (1997) EBIC-guidelines for management of severe head injury in adults. European Brain Injury Consortium. Acta Neurochir (Wien) 139:286–294

    Google Scholar 

  7. Siesjö BK (1978) Brain energy metabolism. Wiley, New York

  8. Persson L, Hillered L (1992) Chemical monitoring of neurosurgical intensive care patients using intracerebral microdialysis. J Neurosurg 76:72–80

    CAS  PubMed  Google Scholar 

  9. Stahl N, Mellergard P, Hallstrom A, Ungerstedt U, Nordstrom CH (2001) Intracerebral microdialysis and bedside biochemical analysis in patients with fatal traumatic brain lesions. Acta Anaesthesiol Scand 45:977–985

    Article  CAS  PubMed  Google Scholar 

  10. Persson L, Valtysson J, Enblad P, Warme PE, Cesarini K, Lewen A, Hillered L (1996) Neurochemical monitoring using intracerebral microdialysis in patients with subarachnoid hemorrhage. J Neurosurg 84:606–616

    CAS  PubMed  Google Scholar 

  11. Hillered L, Persson L (1999) Theory and practice of microdialysis—prospect for future clinical use. Acta Neurochir Suppl (Wien) 75:3–6

    Google Scholar 

  12. Marklund N, Salci K, Lewen A, Hillered L (1997) Glycerol as a marker for post-traumatic membrane phospholipid degradation in rat brain. Neuroreport 8:1457–1461

    CAS  PubMed  Google Scholar 

  13. Unterberg AW, Sakowitz OW, Sarrafzadeh AS, Benndorf G, Lanksch WR (2001) Role of bedside microdialysis in the diagnosis of cerebral vasospasm following aneurysmal subarachnoid hemorrhage. J Neurosurg 94:740–749

    CAS  PubMed  Google Scholar 

  14. Nilsson OG, Brandt L, Ungerstedt U, Saveland H (1999) Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration. Neurosurgery 45:1176–1184

    Article  CAS  PubMed  Google Scholar 

  15. Stahl N, Schalén W, Ungerstedt U, Nordstrom CH (2003) Bedside biochemical monitoring of the penumbra zone surrounding an evacuated acute subdural haematoma. Acta Neurol Scand 108:211–215

    Article  CAS  PubMed  Google Scholar 

  16. Sarrafzadeh AS, Sakowitz OW, Kiening KL, Benndorf G, Lanksch WR, Unterberg AW (2002) Bedside microdialysis: a tool to monitor cerebral metabolism in subarachnoid hemorrhage patients? Crit Care Med 30:1062–1070

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Urban Ungerstedt.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bellander, BM., Cantais, E., Enblad, P. et al. Consensus Meeting on Microdialysis in Neurointensive Care. Intensive Care Med 30, 2166–2169 (2004). https://doi.org/10.1007/s00134-004-2461-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00134-004-2461-8

Keywords

Navigation