Abstract
Background
Sleep problems may lead to, or be symptomatic of, depression and other mental illnesses yet few studies have investigated their association with suicide risk.
Design
Prospective cohort study.
Setting
Taiwan.
Participants
393,983 men and women aged 20 or above participating in the MJ health check-up programme.
Results
There were 335 suicides over a mean of 7.4 years follow-up. There was a reverse J-shaped association between sleep duration and suicide risk. When compared with those sleeping 6–8 h per night the adjusted hazard ratios (95 % confidence intervals) for suicide associated with 0–4, 4–6 and >8 h sleep were 3.5 (2.0–6.1), 1.5 (1.1–1.9) and 1.5 (1.1–2.0), respectively. People requiring sleeping pills to get to sleep (1.2 % participants) were at over 11-fold increased risk; difficulty falling asleep (11.5 % participants), frequent dreaming (16.7 %) and being easily awoken (30.6 %) were associated with a 2.0-, 1.6- and 1.3-fold increased risk of suicide, respectively.
Conclusions
Less than 6 h sleep duration, sleep disturbances and reported use of sleep medicines are markers of suicide risk. Sleep problems should be assessed when evaluating suicide risk.
Similar content being viewed by others
References
Barraclough BM, Pallis DJ (1975) Depression followed by suicide: a comparison of depressed suicides with living depressives. Psychol Med 5:55–61
Bjorngaard JH, Bjerkeset O, Romundstad P, Gunnell D (2011) Sleeping problems and suicide in 75,000 Norwegian adults: a 20 year follow-up of the HUNT I study. Sleep 34:1155–1159
Brower KJ, McCammon RJ, Wojnar M, Ilgen MA, Wojnar J, Valenstein M (2011) Prescription sleeping pills, insomnia, and suicidality in the National Comorbidity Survey Replication. J Clin Psychiatry 72:515–521
Cappuccio FP, D’Elia L, Strazzullo P, Miller MA (2010) Sleep duration and all-cause mortality: a systematic review and meta-analysis of prospective studies. Sleep 33:585–592
Carli V, Roy A, Bevilacqua L, Maggi S, Cesaro C, Sarchiapone M (2011) Insomnia and suicidal behaviour in prisoners. Psychiatry Res 185:141–144
Chang SS, Sterne JA, Lu TH, Gunnell D (2010) ‘Hidden’ suicides amongst deaths certified as undetermined intent, accident by pesticide poisoning and accident by suffocation in Taiwan. Soc Psychiatry Psychiatr Epidemiol 45:143–152
Chang SS, Wen CP, Tsai MK, Lawlor DA, Yang YC, Gunnell D (2012) Adiposity, its related biologic risk factors, and suicide: a cohort study of 542,088 Taiwanese adults. Am J Epidemiol 175:804–815
Dahl RE, Lewin DS (2002) Pathways to adolescent health sleep regulation and behavior. J Adolesc Health 31:175–184
Ferrie JE, Kumari M, Salo P, Singh-Manoux A, Kivimaki M (2011) Sleep epidemiology—a rapidly growing field. Int J Epidemiol 40:1431–1437
Fitzgerald CT, Messias E, Buysse DJ (2011) Teen sleep and suicidality: results from the youth risk behavior surveys of 2007 and 2009. J Clin Sleep Med 7:351–356
Fujino Y, Mizoue T, Tokui N, Yoshimura T (2005) Prospective cohort study of stress, life satisfaction, self-rated health, insomnia, and suicide death in Japan. Suicide Life Threat Behav 35:227–237
Gangwisch JE, Babiss LA, Malaspina D, Turner JB, Zammit GK, Posner K (2010) Earlier parental set bedtimes as a protective factor against depression and suicidal ideation. Sleep 33:97–106
Goodwin RD, Marusic A (2008) Association between short sleep and suicidal ideation and suicide attempt among adults in the general population. Sleep 31:1097–1101
Kripke DF, Garfinkel L, Wingard DL, Klauber MR, Marler MR (2002) Mortality associated with sleep duration and insomnia. Arch Gen Psychiatry 59:131–136
Liu X (2004) Sleep and adolescent suicidal behavior. Sleep 27:1351–1358
McCall WV, Blocker JN, D’Agostino R Jr, Kimball J, Boggs N, Lasater B, Rosenquist PB (2010) Insomnia severity is an indicator of suicidal ideation during a depression clinical trial. Sleep Med 11:822–827
McKnight-Eily LR, Eaton DK, Lowry R, Croft JB, Presley-Cantrell L, Perry GS (2011) Relationships between hours of sleep and health-risk behaviors in US adolescent students. Prev Med 53:271–273
Ohayon MM (2002) Epidemiology of insomnia: what we know and what we still need to learn. Sleep Med Rev 6:97–111
Pigeon WR, Caine ED (2010) Insomnia and the risk for suicide: does sleep medicine have interventions that can make a difference? Sleep Med 11:816–817
Ribeiro JD, Pease JL, Gutierrez PM, Silva C, Bernert RA, Rudd MD, Joiner TE Jr (2012) Sleep problems outperform depression and hopelessness as cross-sectional and longitudinal predictors of suicidal ideation and behavior in young adults in the military. J Affect Disord 136:743–750
Roberts RE, Shema SJ, Kaplan GA, Strawbridge WJ (2000) Sleep complaints and depression in an aging cohort: a prospective perspective. Am J Psychiatry 157:81–88
Rod NH, Vahtera J, Westerlund H, Kivimaki M, Zins M, Goldberg M, Lange T (2010) Sleep disturbances and cause-specific mortality: results from the GAZEL cohort study. Am J Epidemiol 173:300–309
Staner L (2010) Comorbidity of insomnia and depression. Sleep Med Rev 14:35–46
Szklo-Coxe M, Young T, Peppard PE, Finn LA, Benca RM (2010) Prospective associations of insomnia markers and symptoms with depression. Am J Epidemiol 171:709–720
Taiwan Suicide Prevention Center (2010) Trends in suicide rates in Taiwan, 1994–2009. http://www.tspc.doh.gov.tw/tspc/portal/know/index.jsp?type=2 (Accessed 25 Jan 2011)
Tanskanen A, Tuomilehto J, Viinamaki H, Vartiainen E, Lehtonen J, Puska P (2001) Nightmares as predictors of suicide. Sleep 24:844–847
Turvey CL, Conwell Y, Jones MP, Phillips C, Simonsick E, Pearson JL, Wallace R (2002) Risk factors for late-life suicide: a prospective, community-based study. Am J Geriatr Psychiatry 10:398–406
Wen CP, Levy DT, Cheng TY, Hsu CC, Tsai SP (2005) Smoking behaviour in Taiwan, 2001. Tob Control 14:i51–i55
Wen CP, Wai JP, Tsai MK, Yang YC, Cheng TY, Lee MC, Chan HT, Tsao CK, Tsai SP, Wu X (2011) Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study. Lancet 378:1244–1253
Acknowledgments
This study is supported in part by Taiwan Department of Health Clinical Trial and Research Center of Excellence (DOH102-TD-B-111-004). Professor David Gunnell is a UK National Institute for Health Research Senior Investigator. Dr. Shu-Sen Chang’s fellowship at the University of Bristol was funded by the National Science Council, Taiwan (NSC-98-2917-I-564-162). Dr. Shu-Sen Chang was supported by the Hong Kong Research Grants Council (RCG) General Research Fund (HKU784210M and HKU784012M). We thank the institutional support from the National Health Research Institutes, Taiwan. The views in this manuscript are those of the authors and not necessarily any funding bodies or of the MJ Health Management Institution.
Conflict of interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Gunnell, D., Chang, SS., Tsai, M.K. et al. Sleep and suicide: an analysis of a cohort of 394,000 Taiwanese adults. Soc Psychiatry Psychiatr Epidemiol 48, 1457–1465 (2013). https://doi.org/10.1007/s00127-013-0675-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00127-013-0675-1