Abstract
Background
Birth-related factors have been associated with adult chronic disease. Whilst the potential association between these factors and depression in adulthood was been described rather less is known about the role of these exposures in the development of anxiety.
Method
Cross-sectional population-based survey recruited adults aged 18–25 years. Participants were classified on the basis of responses to the Hospital Anxiety and Depression Scale. Birth-related exposures were determined by hospital medical record review. A proportional odds model was used to assess associations between birth factors and anxiety and depression.
Results
No significant associations were found between birth factors and anxiety. Significant associations were found between depression with low birth weight (odds ratio 2.88, 95% confidence interval 1.26–6.59) and neonatal admission to ITU (3.12, 1.25, 7.78).
Conclusion
Low birth weight and neonatal intensive care unit admission are significantly associated with depression in adults. Other birth related variables were not significantly associated with either depression or anxiety.
Similar content being viewed by others
References
Alati R, Lawlor D, Mamun A, Williams G, Najman J, O’Callaghan M, Bor W (2007) Is there a foetal origin to depression? Evidence from the Mater University study of Pregnancy and its outcomes. Am J Epidemiol 165:418–424
Bager P, Melbye M, Rostgaard K, Benn C, Westergaard T (2003) Mode of delivery of risk of allergic rhinitis and asthma. J Allergy Clin Immunol 111:51–55
Barker D (1998) Mothers, babies and health in later life. 2nd edn. Churchill, Livingstone
Baumeister H, Härter M (2007) Prevalence of mental disorders based on general population surveys. Soc Psychiatry Psychiatr Epidemiol 42:537–546
Bjelland I, Dahl A, Haug T, Neckelmann D (2002) The validity of the hospital anxiety and depression scale. An updated literature review. J Psychosom Res 52:69–77
Costello E, Worthman C, Erkanli A, Angold A (2007) Prediction from low birth weight to female adolescent depression. A test of competing hypotheses. Arch Gen Psychiatry 64:338–344
Cwikel J, Zilber N, Feinson M, Lerner Y (2007) Prevalence an risk factors of threshold and sub-threshold psychiatric disorders in primary care. Soc Psychiatry Psychiatr Epidemiol doi:10.1007/s00127-007-0286-9
De Graaf R, Bijl R, Smit F, Vollenbergh W, Spijker J (2004) Risk factors for 12-month comorbidity of mood, anxiety and substance use disorders: findings from the Netherlands mental health survey and incidence study. Am J Psychiatry 159:620–629
Gale C, Ashurst H, Hall N, MacCallum P, Martyn C (2002) Size at birth and carotid atherosclerosis in later life. Atherosclerosis 163:141–147
Gale C, Martyn C (2004) Birth weight and later life depression in a national birth cohort. Br J Psychiatry 184:28–33
Harding J (2001) The nutritional basis of the fetal origins of adult disease. Int J Epidemiol 30:15–23
Jacobi F, Wittchen H, Holting C, Hofler M, Pfister H, Muller N, Lieb R (2004) Prevalence, co-morbidity and correlates of mental disorders in the general population: results from the German Health Interview and Examination Survey (GHS). Psychol Med 34:597–611
Kero J, Gissler M, Gronlund M, Kero P, Koskinen P, Hemminki E, Isolauri E (2002) Mode of delivery and asthma – Is there a connection? Pediatr Res 52:6–11
Kessler K, McGonagle K, Zhao S, Nelson C, Hughes E, Eshleman S, Wittchen M, Kendler K (1994) Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Arch Gen Psychiatry 51:8–19
Law C, Shiell A (1996) Is blood pressure inversely related to birth weight? The strength of evidence from a systematic review of the literature. J Hypertens 14:935–941
Mallen C, Peat G, Thomas E, Croft P (2005) Severely disabling chronic pain in young adults. Prevalence from a population-based postal survey in North Staffordshire. BMC Musculoskelet Disord 6:42
Mallen C, Peat G, Thomas E, Croft P (2006) Is chronic musculoskeletal pain in adulthood related to factors at birth? A population-based case-control study of young adults. Eur J Epidemiol 21:237–243
Mikolajczyk R, Maxwell A, El ansari W, Naydenova V, Stock C, Ilieva S, Dudziak U, Nagyova I (2007) Prevalence of depressive symptoms in university students from Germany, Denmark, Poland and Bulgaria. Soc Psychiatry Psychiatr Epidemiol, doi:10.1007/s00127-007-0282-0
Nomura Y, Wickramaratne P, Pilowsky D, Newcorn J, Bruder-Costello B, Davey C, Fifer W, Brooks-Gunn J, Weissman M (2007) Low birth weight an risk of affective disorders and selected medical illness in offspring at high and low risk for depression. Compr Psychiatry 48:470–478
Osler M, Nordentoft M, Andersen A-M (2005) Birth dimensions and risk of depression in adulthood: cohort study of Danish men born in 1953. Br J Psychiatry 186:400–403
Paile-Hyvärinen, Räikkönen K, Forsén T, Kajantie E, Ylihärsila H, Salonen M, Osmond C, Eriksson J (2007) Depression and its association with diabetes, cardiovascular diease, and birth weight. Ann Med 39:634–640
Patton G, Coffey C, Carlin J, Olsson C, Morley R (2004) Prematurity at birth and adolescent depressive disorder. Br J Psychiatry 184:446–447
Patton G, Hibbert M, Carlin J, Shao Q, Rosler M, Caust J, Bowes G (1996) Menarche and the onset of depression and anxiety in Victoria, Australia. J Epidemiol Community Health 50:661–666
Peters JW, Schouw R, Anand KJ, van Dijk M, Duivenvoorden HJ, Tibboel D (2005) Does neonatal surgery lead to increased pain sensitivity in later childhood? Pain 114:444–454
Peterson B, Harrell F (1990) Partial proportional odds models for ordinal response variables. Appl Stat 39:205–217
Phillips D, Barker D, Fall C, Seckl J, Whorwood C, Wood P, Walker B (1998) Elevated plasma cortisol concentrations: a link between low birth weight and the insulin resistance syndrome? J Clin Endocrinol Metab 83:757–760
Phipps K, Barker D, Hales C, Fall C, Osmond C, Clark P (1993) Fetal growth and impaired glucose tolerance in men and women. Diabetologia 36:225–228
Poulsen P, Vaag A, Kyvik K, Moller Jensen D, Beck-Nielsen H (1997) Low birth weight is associated with NIDDM in discordant monozygotic and dizygotic twin pairs. Diabetologia 40:439–446
Rich-Edwards J, Stampfer M, Manson J, Rosner B, Harkinson S, Colditz G, Willett W, Hennekens C (1997) Birth weight and risk of cardiovascular disease in a cohort of women followed up since 1976. BMJ 315:396–400
Robinson S, Walton R, Clark P, Barker D, Hales C, Osmond C (1992) The relation of foetal growth to plasma glucose in young men. Diabetologia 35:444–446
Räikkönen K, Pesonen A-K, Kajantie E, Heinonen K, Forsén T, Phillips D, Osmond C, Barker D, Eriksson J (2007) Length of gestation and depressive symptoms at age 60 years. Br J Psychiatry 190:469–474
Taddio A, Katz J, Ilerisch AL, Koren G (1997) Effect of neonatal circumcision on pain response during subsequent routine vaccination in boys. Lancet 349:599–603
Thompson C, Syddall H, Rodin I, Osmond C, Barker D (2001) Birth weight and risk of depressive disorder in later life. Br J Psychiatry 179:450–455
Wright A, Jorm A, Harris M, McGorry P (2007) What’s in a name? Is accurate recognition and labelling of mental disorders by young people associated with better help-seeking and treatment preferences? Soc Psychiatry Psychiatr Epidemiol doi:10.1007/s00127-006-0156-x
Zigmond A, Snaith R (1983) The hospital anxiety and depression scale (HAD). Acta Psychiatr Scand 67:361–370
Acknowledgments
The authors would like to thank the practices and patients who participated in this study. We would also like to thank the Primary Care Musculoskeletal Research Centre Administration team and the Keele GP Research Partnership Team for their help. Special thanks are extended to Dr George Peat and Professor Peter Croft for their help in designing the study and for comments earlier drafts of this article. An Arthritis Research Campaign Primary Care Fellowship funds Dr. Christian Mallen.
Conflict of interest statement
CM and ET were involved in the conception, design and conduct of the study. All authors contributed to the analysis and drafting of the article. All authors approved the final draft. All authors declare they have no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Mallen, C., Mottram, S. & Thomas, E. Birth factors and common mental health problems in young adults. Soc Psychiat Epidemiol 43, 325–330 (2008). https://doi.org/10.1007/s00127-007-0304-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00127-007-0304-y