Abstract
In the 20 years since its introduction, radial access for diagnostic and interventional coronary procedures has been well validated in countless scientific studies. Nevertheless, the use of this access route varies greatly among—and even within—countries. Fear of the unknown may make some experienced interventionalists hesitant to adopt the transradial approach in spite of its proven advantages. In our review, we describe practical aspects of the transradial access, such as the role of Allen’s test in patient selection and considerations on the optimal puncture technique of the radial artery. Catheter selection, anatomic variations which may complicate access, as well as strategies to avoid and/or manage possible complications are outlined. Finally, we review the literature on the reduction of access site complications by adopting the transradial approach. Even in interventions for acute myocardial infarction, transradial access can be used safely and effectively. In addition to a reduced rate of access site complications, a reduction in overall in-hospital major adverse cardiac events has been demonstrated. The advantage regarding access site complications could be seen even when closure devices were utilized for transfemoral procedures.
Zusammenfassung
Etwa 20 Jahre nach Einführung des transradialen Zugangs für Herzkatheteruntersuchungen und Koronarinterventionen sind die Vorteile dieses Verfahrens im Vergleich zum transfemoralen Vorgehen gut untersucht; dennoch kommt es unterschiedlich häufig zur Anwendung. In dieser Arbeit werden praktische Aspekte des transradialen Zugangs dargestellt, die Bedeutung des Allen-Tests bei der Auswahl geeigneter Patienten und die optimale Punktionstechnik der A. radialis. Anatomische Varianten der A. radialis können Probleme verursachen und müssen bedacht werden. Zur Koronarangiographie werden üblicherweise Standardkatheter wie beim transfemoralen Vorgehen verwendet. Komplikationen sind bei der Beachtung von wenigen, wichtigen Grundregeln selten und können in der Regel sicher gehandhabt werden. In klinischen Untersuchungen wurde gezeigt, dass Blutungen im Rahmen von Koronarinterventionen mit einem schlechteren Outcome verbunden sind. Durch die Anwendung des transradialen Zugangs können Blutungen an der Punktionsstelle signifikant verringert werden. Auch bei akuten Myokardinfarkten kann der transradiale Zugang sicher eingesetzt werden; im Vergleich zur transfemoralen Technik ließ sich nicht nur eine geringere Komplikationsrate an der Punktionsstelle, sondern auch ein besseres kardiovaskuläres Outcome nachweisen. Selbst beim Einsatz von Verschlusssystemen im Rahmen des femoralen Zugangs zeigte sich bezüglich der Komplikationsrate ein Vorteil für den transradialen Zugang.
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References
Radner S (1948) Thoracal aortography by catheterization from the radial artery; preliminary report of a new technique. Acta Radiol 29:178–180
Campeau L (1989) Percutaneous radial artery approach for coronary angiography. Cathet Cardiovasc Diagn 16:3–7
Kiemeneij F (1989) Transradial coronary artery angioplasty. Am Heart J 129:1–7
Kiemeneij F, Laaraman GJ (1994) Percutaneous transradial artery approach for coronary Palmaz-Schatz stent implantation. Am Heart J 128:167–174
Rao SV, Ou FS, Wang TY et al (2008) Trends in the prevalence and outcomes of radial and femoral approaches to percutaneous coronary intervention: a report from the National Cardiovascular Data Registry. JACC Cardiocasc Interv 1:379–386
Doganov A (2010) The radial approach: en route to routine? EuroIntervention 6:175–177
Benit E, Vranckx, Jaspers L, Jackmaert et al (1996) Frequency of a positive modified Allen’s test in 1000 consecutive patients undergoing cardiac catheterization. Cathet Cardiovasc Diagn 38(4):352–354
Barbeau GR, Arsenault F, Dugas L et al (2004) Evaluation of the ulnopalmar arterial arches with pulse oximetry and plethysmography: comparison with the Allen’s test in 1,010 patients. Am Heart J 147:489–493
Gilchrist IC (2008) Radial complications: rare but critical. Cardiac Interventions Today 39–42
Stella PR, Kiemeneij F, Laarman GJ, Odekerken D et al (1997) Incidence and outcomes of radial artery occlusion following transradial artery coronary angioplasty. Cathet Cardiovasc Diagn 40:156–158
Louvard Y, Ludwig J (2008) The radial approach to angiography and intervention. Cordis Europe
Ludwig J, Achenbach S, Flachskampf FA (2010) Transradial approach: a modified puncture technique for arterial access. EuroIntervention 6:280–282
Freestone B, Nolan J (2010) Transradial cardiac procedures: the state of the art. Heart 96:883–891
Nie B, Zhou YJ, Li GZ, Shi DM et al (2009) Clinical study of arterial anatomic variations for transradial coronary procedure in Chinese population. Chin Med J 122:2097–2102
Bertrand OF, Rao SV, Pancholy S, Jolly SS et al (2010)Transradial approach for coronary angiography and interventions: results of the first international transradial practice survey. JACC Cardiovasc Interv 3:102–1031
Eltahawy EA, Cooper CJ (2010) Managing radial access vascular complications. Cardiac Interventions Today 46–49
Zankl AR, Andrassy M, Volz C, Ivandic B et al (2010) Radial artery thrombosis following transradial coronaty angiography: incidence and rationale for treatment of symptomatic patients with low-molecular-weight heparins. Clin Res Cardiol 99:841–847
Brueck M, Bandorski D, Kramer W, Wieczorek M et al (2009) A randomized comparison of transradial versus transfemoral approach for coronary angiography and angioplasty. JACC Cardiovasc Interv 2:1047–1054
Moscucci M, Fox KA, Cannon CP, Klein W et al (2003) Predictors of major bleeding in acute coronary syndrome: the Global Registry of Acute Coronary Events (GRACE). Eur Heart J 24:1815–1823
Kinnard TD, Stabile E, Mintz GS, Lee CW et al (2003) Incidence, predictors and prognostic implications of bleeding and blood transfusion following percutaneous coronary interventions. Am J Cardiol 92:930–935
Fuchs S, Kornowski R, Teplitsky I, Brosh D et al (2009) Major bleeding complicating contemporary primary percutaneous coronary interventions- incidence, predictors and prognostic implications. Cardiovasc Revasc Med 10:88–93
Yatskar L, Selzer F, Feit F, Cohen HA et al (2007) Access site hematoma reqiring blood transfusion predicts mortality in patients undergoing percutaneous coronary intervention: data from the National Heart, Lung, and Blood Institute Dynamic Registry. Catheter Cardiovasc Interv 69:961–966
Manoukian SV, Feit F, Mehran R, Voeltz MD et al (2007) Impact of major bleeding on 30-day-mortality and clinical outcomes in patients with acute coronary syndromes: an analysis from the ACUITY Trial. J Am Coll Cardiol 49:1362–1368
Rao SV, O’Grady K, Pieper KS, Grnager CB et al (2005) Impact of bleeding severity on clinical outcomes among patients with acute coronary syndromes. Am J Cardiol 96:1200–1206
Kiemeneij F, Laarman GJ, Odekerken D, Slagboom T et al (1997) Arandomized comparison of percutaneous transluminal coronary angioplasty by the radial, brachial and femoral approaches: the access study. J Am Coll Cardiol 29:1269–1275
Mann JT, Cubeddhu MG, Schneider JE, Arrowood M (1996) Right radial Access for PTCA: A prospective study demonstrates reduced complications and hospital charges. J Invasive Cardiol 8[Suppl D]:40–44
Pristipino C, Trani C, Nazzaro MS, Berni A et al (2009) Major improvement of percutaneous cardiovascular procedure outcomes with radial artery catheterization: results from the PREVAIL study. Heart 95:476–482
Chase AJ, Fretz EB, Warburton WP, Klinke WP et al (2008) Association of the arterial access site at angioplasty with transfusion and mortality: the M.O.R.T.A.L study (mortality benefit of reduced transfusion after percutaneous coronary intervention via the arm or leg). Heart 94:1019–1025
Jolly SS, Amlani S, Hamon M, Yusuf S et al (2009) Radial versus femoral access for coronary angiography or intervention and the impact on major bleeding and ischemic events: a systematic review and meta-analysis of randomized trials. Am Heart J 157:132–140
Louvard Y, Benamer H, Garot P, Hildick-Smith D et al (2004) Comparison of transradial and transfemoral approaches for coronary angiography and angioplasty in octogenarians (the OCTOPLUS study). Am J Cardiol 94:1177–1180
Achenbach S, Ropers D, Kallert L, Turan N et al (2008) Transradial versus transfemoral approach for coronary angiography and intervention in patients above 75 years of age. Catheter Cardiovasc Interv 72:629–635
Steg G, Aubry P (1996) Radial access for primary PTCA in patients with acute myocardial infarction and contraindication or impossible femoral access. Catheter Cardiovasc Diagn 39:424–426
Ochiai M, Isshiki T, Toyoizumi H, Eto K at al (1999) Efficacy of transradial primary stenting in patients witch acute myocardial infarction. Am J Cardiol 83:966–968
Mulukutla SR, Cohen HA (2002) Feasibilty and efficacy of transradial access for coronary interventions in patients with acute myocardial infarction. Catheter Cardiovasc Interv 57:167–171
Louvard Y, Ludwig J, Levevre T, Schmeisser A et al (2002) Transradial approach for coronary angioplasty in the setting of acute myocardial infarction: a dual center registry. Catheter Cardiovasc Interv 55:206–211
Saito S, Tanaka S, Hiroe Y, Miyashita Y et al (2003) Comparative study on transradial approach vs. transfemoral approach in primary stent implantation for patients with acute myocardial infarction: results of the test for myocardial infarction by prospective unicenter randomization for access sites (TEMPURA) trial. Catheter Cardiovasc Interv 59:26–33
Cantor WJ, Puley G, Natarajan MK, Dzavik V et al (2005) Radial versus femoral access for emergent percutaneous coronary intervention with adjunct glycoprotein IIb/IIIa inhibition in acute myocardial infarction-the RADIAL-AMI pilot randomized trial. Am Heart J 150:543–549
Hetherington SL, Adam Z, Morley R, Belder MA de et al (2009) Primary percutaneous coronary intervention for acute ST-segment elevation myoacardial infarction: changing patterns of vascular access, radial versus femoral artery. Heart 95:1608–1612
Vorobcsuk A, Konyi A, Aradi D, Horvath IG et al (2009) Transradial versus transfemoral percutaneous coronary intervention in acute myocardial infarction: Systemic overview and meta-analysis. Am Heart J 158:14–21
Nikolsky E, Mehran R, Halkin A, Aymong ED et al (2004) Vascular complications associated with arteriotomy closure devices in patients undergoing percutaneous coronary procedures: a meta-analysis. J Am Coll Cardiol 44:1200–1209
Patel MR, Jneid H, Derdeyn CP, Klein LW et al (2010) Arteriotomy closure devices for cardiovascular procedures: a scientific statement from the American Heart Association. Circulation 122:1882–1893
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The corresponding author states that he has a consultancy contract with the company B. Braun.
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Ludwig, J., Achenbach, S., Daniel, W. et al. The transradial approach. Herz 36, 386–395 (2011). https://doi.org/10.1007/s00059-011-3483-y
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DOI: https://doi.org/10.1007/s00059-011-3483-y