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Gepubliceerd in: Huisarts en wetenschap 13/2009

01-01-2009 | Onderzoek

Stapsgewijze preventie van angst en depressie bij ouderen

Uitkomsten van een gerandomiseerd onderzoek

Auteurs: Nelleke van ´t Veer-Tazelaar, Harm van Marwijk, Patricia van Oppen, Hein van Hout, Henriëtte van der Horst, Pim Cuijpers, Filip Smit, Aartjan Beekman

Gepubliceerd in: Huisarts en wetenschap | Uitgave 13/2009

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Samenvatting

Van ’t Veer-Tazelaar PJ, Van Marwijk HWJ, Van Oppen P, Van Hout HPJ, Van der Horst HE, Cuijpers P, Smit F, Beekman ATF. Stapsgewijze preventie van angst en depressie bij ouderen. Uitkomsten van een gerandomiseerd onderzoek. Huisarts Wet 2009;52(13):668-73.
Doel Het bepalen van de doeltreffendheid van een geïndiceerd angst- en depressiepreventieprogramma voor ouderen.
Methode Het betrof een gerandomiseerd en gecontroleerd onderzoek. Rekrutering vond plaats tussen 1 oktober 2004 en 1 oktober 2005 in 33 huisartsenpraktijken in West-Friesland. Aan dit onderzoek deden 170 ouderen (75-plus) met subklinische depressie of angst mee. We wezen de deelnemers willekeurig toe aan een preventief stapsgewijs zorgprogramma (n = 86) of aan gebruikelijke zorg (n = 84). Het stapsgewijze zorgprogramma bestond uit vier fasen: 1) watchful waiting, 2) op cognitieve gedragstherapie gebaseerde bibliotherapie, 3) het aanleren van een op cognitieve gedragstherapie gebaseerde probleemoplossingsmethode en 4) een (terug)verwijzing naar de huisarts om een eventuele medicamenteuze aanpak te bespreken. Primaire uitkomst was de cumulatieve incidentie, na een jaar, van een depressie of angststoornis die voldoet aan DSM-IV-criteria, zoals vastgesteld door middel van het Mini International Neuropsychiatric Interview (MINI).
Resultaten De interventie halveerde de eenjaarsincidentie van depressie- en angststoornissen, van 0,24 (20 van 84) in de gebruikelijke zorggroep naar 0,12 (10 van 86) in de groep die het stapsgewijze zorgprogramma aangeboden had gekregen (RR 0,49; 95%-BI 0,24 – 0,98).
Conclusie Geïndiceerde stapsgewijze preventie van depressie en angst bij ouderen halveerde het risico op het ontwikkelen van deze stoornissen. Dit onderzoek werd gefinancierd door ZonMw (2620.0003).
Literatuur
go back to reference Beekman AT, De Beurs E, Van Balkom AJ, Deeg DJ, Van Dyck R, Van Tilburg W. Anxiety and depression in later life: Co-occurrence and communality of risk factors. Am J Psychiatry 2000;157:89-95. Beekman AT, De Beurs E, Van Balkom AJ, Deeg DJ, Van Dyck R, Van Tilburg W. Anxiety and depression in later life: Co-occurrence and communality of risk factors. Am J Psychiatry 2000;157:89-95.
go back to reference Reynolds CF III, Kupfer DJ. Depression and aging: a look to the future. Psychiatr Serv 1999;50:1167-72. Reynolds CF III, Kupfer DJ. Depression and aging: a look to the future. Psychiatr Serv 1999;50:1167-72.
go back to reference De Beurs E, Beekman A, Geerlings S, Deeg D, Van Dyck R, Van Tilburg W. On becoming depressed or anxious in late life: similar vulnerability factors but different effects of stressful life events. Br J Psychiatry 2001;179:426-31. De Beurs E, Beekman A, Geerlings S, Deeg D, Van Dyck R, Van Tilburg W. On becoming depressed or anxious in late life: similar vulnerability factors but different effects of stressful life events. Br J Psychiatry 2001;179:426-31.
go back to reference Diefenbach GJ, Goethe J. Clinical interventions for late-life anxious depression. Clin Interv Aging 2006;1:41-50. Diefenbach GJ, Goethe J. Clinical interventions for late-life anxious depression. Clin Interv Aging 2006;1:41-50.
go back to reference Pinquart M, Duberstein PR, Lyness JM. Treatments for later-life depressive conditions: a meta-analytic comparison of pharmacotherapy and psychotherapy. Am J Psychiatry 2006;163:1493-1501. Pinquart M, Duberstein PR, Lyness JM. Treatments for later-life depressive conditions: a meta-analytic comparison of pharmacotherapy and psychotherapy. Am J Psychiatry 2006;163:1493-1501.
go back to reference Andrews G, Issakidis C, Sanderson K, Corry J, Lapsley H. Utilising survey data to inform public policy: comparison of the cost-effectiveness of treatment of ten mental disorders. Br J Psychiatry 2004;184:526-33. Andrews G, Issakidis C, Sanderson K, Corry J, Lapsley H. Utilising survey data to inform public policy: comparison of the cost-effectiveness of treatment of ten mental disorders. Br J Psychiatry 2004;184:526-33.
go back to reference Chisholm D, Sanderson K, Ayuso-Mateos JL, Saxena S. Reducing the global burden of depression: population-level analysis of intervention cost-effectiveness in 14 world regions. Br J Psychiatry 2004;184:393-403. Chisholm D, Sanderson K, Ayuso-Mateos JL, Saxena S. Reducing the global burden of depression: population-level analysis of intervention cost-effectiveness in 14 world regions. Br J Psychiatry 2004;184:393-403.
go back to reference Wisniewski SR, Fava M, Trivedi MH, Thase ME, Warden D, Niederehe G, et al. Acceptability of second-step treatments to depressed outpatients: a STAR*D report. Am J Psychiatry 2007;164:753-60. Wisniewski SR, Fava M, Trivedi MH, Thase ME, Warden D, Niederehe G, et al. Acceptability of second-step treatments to depressed outpatients: a STAR*D report. Am J Psychiatry 2007;164:753-60.
go back to reference Turner EH, Matthews AM, Linardatos E, Tell RA, Rosenthal R. Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med 2008;358:252-60. Turner EH, Matthews AM, Linardatos E, Tell RA, Rosenthal R. Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med 2008;358:252-60.
go back to reference Mrazek P, Haggerty RJ. Reducing risks for mental disorders. Washington DC: National Academy Press, 1994. Mrazek P, Haggerty RJ. Reducing risks for mental disorders. Washington DC: National Academy Press, 1994.
go back to reference Smit F, Ederveen A, Cuijpers P, Deeg D, Beekman A. Opportunities for cost-effective prevention of late-life depression: an epidemiological approach. Arch Gen Psychiatry 2006;63:290-6. Smit F, Ederveen A, Cuijpers P, Deeg D, Beekman A. Opportunities for cost-effective prevention of late-life depression: an epidemiological approach. Arch Gen Psychiatry 2006;63:290-6.
go back to reference Smit F, Comijs H, Schoevers R, Cuijpers P, Deeg D, Beekman A. Target groups for the prevention of late-life anxiety. Br J Psychiatry 2007;190:428-34. Smit F, Comijs H, Schoevers R, Cuijpers P, Deeg D, Beekman A. Target groups for the prevention of late-life anxiety. Br J Psychiatry 2007;190:428-34.
go back to reference Schoevers RA, Smit F, Deeg DJ, Cuijpers P, Dekker J, Van Tilburg W, et al. Prevention of late-life depression in primary care: do we know where to begin? Am J Psychiatry 2006;163:1611-21. Schoevers RA, Smit F, Deeg DJ, Cuijpers P, Dekker J, Van Tilburg W, et al. Prevention of late-life depression in primary care: do we know where to begin? Am J Psychiatry 2006;163:1611-21.
go back to reference Cole MG. Brief interventions to prevent depression in older subjects: a systematic review of feasibility and effectiveness. Am J Geriatr Psychiatry 2008;16:435-43. Cole MG. Brief interventions to prevent depression in older subjects: a systematic review of feasibility and effectiveness. Am J Geriatr Psychiatry 2008;16:435-43.
go back to reference Cuijpers P, Van Straten A, Smit F. Preventing the incidence of new cases of mental disorders: a meta-analytic review. J Nerv Ment Dis 2005;193:119-25. Cuijpers P, Van Straten A, Smit F. Preventing the incidence of new cases of mental disorders: a meta-analytic review. J Nerv Ment Dis 2005;193:119-25.
go back to reference Cuijpers P, Van Straten A, Smit F, Mihalopoulos C, Beekman A. Preventing the onset of depressive disorders: a meta-analytic review of psychological interventions. Am J Psychiatry 2008;165:1272-80. Cuijpers P, Van Straten A, Smit F, Mihalopoulos C, Beekman A. Preventing the onset of depressive disorders: a meta-analytic review of psychological interventions. Am J Psychiatry 2008;165:1272-80.
go back to reference Haaga DA. Introduction to the special section on stepped care models in psychotherapy. J Consult Clin Psychol 2000;68:547-8. Haaga DA. Introduction to the special section on stepped care models in psychotherapy. J Consult Clin Psychol 2000;68:547-8.
go back to reference Hunkeler EM, Katon W, Tang L, Williams JW Jr, Kroenke K, Lin EH, et al. Long term outcomes from the IMPACT randomised trial for depressed elderly patients in primary care. BMJ 2006;332:259-63. Hunkeler EM, Katon W, Tang L, Williams JW Jr, Kroenke K, Lin EH, et al. Long term outcomes from the IMPACT randomised trial for depressed elderly patients in primary care. BMJ 2006;332:259-63.
go back to reference Jansen AP, Van Hout HP, Van Marwijk HW, Nijpels G, De Bruijne MC, Bosmans JE, et al. (Cost)-effectiveness of case-management by district nurses among primary informal caregivers of older adults with dementia symptoms and the older adults who receive informal care: design of a randomized controlled trial [ISCRTN83135728]. BMC Public Health 2005;5:133. Jansen AP, Van Hout HP, Van Marwijk HW, Nijpels G, De Bruijne MC, Bosmans JE, et al. (Cost)-effectiveness of case-management by district nurses among primary informal caregivers of older adults with dementia symptoms and the older adults who receive informal care: design of a randomized controlled trial [ISCRTN83135728]. BMC Public Health 2005;5:133.
go back to reference Van ’t Veer-Tazelaar PJ, Van Marwijk HW, Jansen AP, Rijmen F, Kostense PJ, Van Oppen P, et al. Depression in old age (75+), the PIKO study. J Affect Disord 2007;106:295-9. Van ’t Veer-Tazelaar PJ, Van Marwijk HW, Jansen AP, Rijmen F, Kostense PJ, Van Oppen P, et al. Depression in old age (75+), the PIKO study. J Affect Disord 2007;106:295-9.
go back to reference Van ’t Veer-Tazelaar PJ, Van Marwijk HW, Van Oppen P, Van Hout HP, Van der Horst HE, Cuijpers P, et al. Stepped-care prevention of anxiety and depression in late life: a randomized controlled trial. Arch Gen Psychiatry 2009;66:297-304. Van ’t Veer-Tazelaar PJ, Van Marwijk HW, Van Oppen P, Van Hout HP, Van der Horst HE, Cuijpers P, et al. Stepped-care prevention of anxiety and depression in late life: a randomized controlled trial. Arch Gen Psychiatry 2009;66:297-304.
go back to reference Antonuccio DO, Steinmetz JL, Lewinsohn PM, Teri L. The Coping with Depression course: A psychoeducational intervention for unipolar depression. Eugene, Oregon: Castalia Publishing Company, 1984. Antonuccio DO, Steinmetz JL, Lewinsohn PM, Teri L. The Coping with Depression course: A psychoeducational intervention for unipolar depression. Eugene, Oregon: Castalia Publishing Company, 1984.
go back to reference Haringsma R, Engels GI, Cuijpers P, Spinhoven P. Effectiveness of the Coping With Depression (CWD) course for older adults provided by the community-based mental health care system in the Netherlands: a randomized controlled field trial. Int Psychogeriatr 2006;18:307-25. Haringsma R, Engels GI, Cuijpers P, Spinhoven P. Effectiveness of the Coping With Depression (CWD) course for older adults provided by the community-based mental health care system in the Netherlands: a randomized controlled field trial. Int Psychogeriatr 2006;18:307-25.
go back to reference Cuijpers P. A psycho-educational approach to the treatment of depression: a meta-analysis of Lewinsohn’s ‘Coping with Depression’ course. Behav Ther 1998;29:521-33. Cuijpers P. A psycho-educational approach to the treatment of depression: a meta-analysis of Lewinsohn’s ‘Coping with Depression’ course. Behav Ther 1998;29:521-33.
go back to reference Radloff LS, Teri L. Use of the Center for Epidemiological Studies-Depression Scale with older adults. Clin Gerontol 1986;5:119-36. Radloff LS, Teri L. Use of the Center for Epidemiological Studies-Depression Scale with older adults. Clin Gerontol 1986;5:119-36.
go back to reference Breslau N. Depressive symptoms, major depression, and generalized anxiety: a comparison of self-reports on CES-D and results from diagnostic interviews. Psychiatry Res 1985;15:219-29. Breslau N. Depressive symptoms, major depression, and generalized anxiety: a comparison of self-reports on CES-D and results from diagnostic interviews. Psychiatry Res 1985;15:219-29.
go back to reference Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, et al. The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 1998;59 Suppl 20:22-33. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E, et al. The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 1998;59 Suppl 20:22-33.
go back to reference Pinninti NR, Madison H, Musser E, Rissmiller D. MINI International Neuropsychiatric Schedule: clinical utility and patient acceptance. Eur Psychiatry 2003;18:361-4. Pinninti NR, Madison H, Musser E, Rissmiller D. MINI International Neuropsychiatric Schedule: clinical utility and patient acceptance. Eur Psychiatry 2003;18:361-4.
go back to reference Rovner BW, Casten RJ, Hegel MT, Leiby BE, Tasman WS. Preventing depression in age-related macular degeneration. Arch Gen Psychiatry 2007;64:886-92. Rovner BW, Casten RJ, Hegel MT, Leiby BE, Tasman WS. Preventing depression in age-related macular degeneration. Arch Gen Psychiatry 2007;64:886-92.
Metagegevens
Titel
Stapsgewijze preventie van angst en depressie bij ouderen
Uitkomsten van een gerandomiseerd onderzoek
Auteurs
Nelleke van ´t Veer-Tazelaar
Harm van Marwijk
Patricia van Oppen
Hein van Hout
Henriëtte van der Horst
Pim Cuijpers
Filip Smit
Aartjan Beekman
Publicatiedatum
01-01-2009
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Huisarts en wetenschap / Uitgave 13/2009
Print ISSN: 0018-7070
Elektronisch ISSN: 1876-5912
DOI
https://doi.org/10.1007/BF03085837

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