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Gepubliceerd in: Tijdschrift voor Kindergeneeskunde 2/2008

01-04-2008

Immunotherapie op de kinderleeftijd

Auteurs: H. deGroot, E. H. G. vanLeer

Gepubliceerd in: Tijdschrift voor Kindergeneeskunde | Uitgave 2/2008

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Samenvatting

Specifieke immunotherapie met allergeenextracten heeft als doel een atopische patiënt minder gevoelig te maken voor een specifiek allergeen (hyposensibilisatie). Bij kinderen is vooralsnog alleen subcutane immunotherapie bewezen effectief. Deze therapie kan worden toegepast bij kinderen met allergische rinoconjunctivitis en/of mild tot matig ernstig astma veroorzaakt door een allergie voor graspollen, boompollen, huisstofmijt of kat. Subcutane immunotherapie voor insecten kan toegepast worden na een doorgemaakte levensbedreigende anafylactische reactie op een insectensteek. Dit artikel beschrijft de indicaties, effectiviteit, contraindicaties, veiligheid en praktische uitvoering van subcutane immunotherapie bij kinderen. Tevens wordt een overzicht gegeven van de andere vormen van immunotherapie, te weten sublinguale en nasale immunotherapie.
Literatuur
1.
go back to reference Bousquet J, Lockey RF, Malling HJ. Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper. Allergy. 1998; 53(Suppl 44):1-42. Bousquet J, Lockey RF, Malling HJ. Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper. Allergy. 1998; 53(Suppl 44):1-42.
2.
go back to reference Bousquet J, Cauwenberge P van, Khaltaev N. Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol. 2001;108:S147-334. Bousquet J, Cauwenberge P van, Khaltaev N. Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol. 2001;108:S147-334.
3.
go back to reference Groot H de. Allergie voor insecten. Huisarts Wet. 2002;45:362-7. Groot H de. Allergie voor insecten. Huisarts Wet. 2002;45:362-7.
4.
go back to reference Bonifazi F, Jutel M, Bilo BM, et al.; EAACI Interest Group on Insect Venom Hypersensitivity. Prevention and treatment of Hymenoptera venom allergy: guidelines for clinical practice. Allergy. 2005; 60:1459-70. Bonifazi F, Jutel M, Bilo BM, et al.; EAACI Interest Group on Insect Venom Hypersensitivity. Prevention and treatment of Hymenoptera venom allergy: guidelines for clinical practice. Allergy. 2005; 60:1459-70.
5.
go back to reference Hauk PK, Friedl K, Kaufmehl K, et al. Subsequent insect stings in children with hypersensitivity to Hymenoptera. J Pediatr. 1995;126:185-90. Hauk PK, Friedl K, Kaufmehl K, et al. Subsequent insect stings in children with hypersensitivity to Hymenoptera. J Pediatr. 1995;126:185-90.
6.
go back to reference Valentine MD, Schuberth KC, Kagey-Sobotka A, et al. The value of immunotherapy with venom in children with allergy to insect stings. N Engl J Med. 1990;323:1601-3. Valentine MD, Schuberth KC, Kagey-Sobotka A, et al. The value of immunotherapy with venom in children with allergy to insect stings. N Engl J Med. 1990;323:1601-3.
7.
go back to reference Wilson DR, Torres Lima M, Durham DR. Sublingual immunotherapy for allergic rhinitis: systemic review and meta-analysis. Allergy. 2005;60:4-12. Wilson DR, Torres Lima M, Durham DR. Sublingual immunotherapy for allergic rhinitis: systemic review and meta-analysis. Allergy. 2005;60:4-12.
8.
go back to reference Roder E, Berger MY, Groot H de, et al. Immunotherapy in children and adolescents with allergic rhinoconjunctivitis: a systematic review. Pediatr Allergy Immunol. 2008 Jan 24; Epub ahead of print. Roder E, Berger MY, Groot H de, et al. Immunotherapy in children and adolescents with allergic rhinoconjunctivitis: a systematic review. Pediatr Allergy Immunol. 2008 Jan 24; Epub ahead of print.
9.
go back to reference Roder E, Berger MY, Hop WC, et al. Sublingual immunotherapy with grass pollen is not effective in symptomatic youngsters in primary care. J Allergy Clin Immunol. 2007;119:892-8. Roder E, Berger MY, Hop WC, et al. Sublingual immunotherapy with grass pollen is not effective in symptomatic youngsters in primary care. J Allergy Clin Immunol. 2007;119:892-8.
10.
go back to reference Calamita Z, Saconato H, Pela AB, et al. Efficacy of sublingual immunotherapy in asthma: systematic review of randomized-clinical trials using the Cochrane Collaboration method. Allergy. 2006; 61:1162-72. Calamita Z, Saconato H, Pela AB, et al. Efficacy of sublingual immunotherapy in asthma: systematic review of randomized-clinical trials using the Cochrane Collaboration method. Allergy. 2006; 61:1162-72.
11.
go back to reference Pajno GB, Caminiti L, Vita D, et al. Sublingual immunotherapy in mite-sensitized children with atopic dermatitis: a randomized, double-blind, placebo-controlled study. J Allergy Clin Immunol. 2007;120:164-70. Pajno GB, Caminiti L, Vita D, et al. Sublingual immunotherapy in mite-sensitized children with atopic dermatitis: a randomized, double-blind, placebo-controlled study. J Allergy Clin Immunol. 2007;120:164-70.
12.
go back to reference Holt PG, Vines J, Britten D. Sublingual allergen administration. I. Selective suppression of IgE production in rats by high allergen doses. Clin Allergy. 1988;18:229-34. Holt PG, Vines J, Britten D. Sublingual allergen administration. I. Selective suppression of IgE production in rats by high allergen doses. Clin Allergy. 1988;18:229-34.
13.
go back to reference Macatinia SE, Hosken NA, Litton M, et al. Dendritic cells produce IL-12 and direct the development of Thl cells from naive CD4+ T cells. J Immunol. 1995;154:5071-9. Macatinia SE, Hosken NA, Litton M, et al. Dendritic cells produce IL-12 and direct the development of Thl cells from naive CD4+ T cells. J Immunol. 1995;154:5071-9.
14.
go back to reference Novak N, Allam J-P, Betten H, et al. The role of antigen presenting cells at distinct anatomic sites: they accelerate and they slow down allergies. Allergy. 2004;59:5-14. Novak N, Allam J-P, Betten H, et al. The role of antigen presenting cells at distinct anatomic sites: they accelerate and they slow down allergies. Allergy. 2004;59:5-14.
15.
go back to reference Bagnasco M, Mariani G, Passalacqua G, et al. Absorption and distribution kinetics of the major Parietaria judaica allergen (Par j 1) administered by noninjectable routes in healthy human beings. J Allergy Clin Immunol. 1997;100:122-9. Bagnasco M, Mariani G, Passalacqua G, et al. Absorption and distribution kinetics of the major Parietaria judaica allergen (Par j 1) administered by noninjectable routes in healthy human beings. J Allergy Clin Immunol. 1997;100:122-9.
16.
go back to reference Businco L, Zannino L, Cantani A, et al. Systemic reactions to specific immunotherapy in children with respiratory allergy: a prospective study. Pediatr Allergy Immunol. 1995;6:44-7. Businco L, Zannino L, Cantani A, et al. Systemic reactions to specific immunotherapy in children with respiratory allergy: a prospective study. Pediatr Allergy Immunol. 1995;6:44-7.
17.
go back to reference Coifman RE, Cox LS; Immunotherapy and Allergy Diagnosics Committee of the AAAAI. 2006 American Academy of Allergy, Asthma & Immunology member immunotherapy practice patterns and concerns. J Allergy Clin Immunol. 2007;119:1012-3. Coifman RE, Cox LS; Immunotherapy and Allergy Diagnosics Committee of the AAAAI. 2006 American Academy of Allergy, Asthma & Immunology member immunotherapy practice patterns and concerns. J Allergy Clin Immunol. 2007;119:1012-3.
18.
go back to reference Di Rienzo V, Pagani A, Parmiani S, et al. Post-marketing surveillance study on the safety of sublingual immunotherapy in pediatric patients. Allergy. 1999;54:1110-3. Di Rienzo V, Pagani A, Parmiani S, et al. Post-marketing surveillance study on the safety of sublingual immunotherapy in pediatric patients. Allergy. 1999;54:1110-3.
19.
go back to reference Fiocchi A, Pajno G, La Grutta S, et al. Safety of sublingual-swallow immunotherapy in children aged 3 to 7 years. Ann Allergy Asthma Immunol. 2005;95:254-8. Fiocchi A, Pajno G, La Grutta S, et al. Safety of sublingual-swallow immunotherapy in children aged 3 to 7 years. Ann Allergy Asthma Immunol. 2005;95:254-8.
20.
go back to reference Enrique E, Pineda F, Malek T, et al. Sublingual immunotherapy for hazelnut food allergy: A randomized, double-blind, placebo-controlled study with a standardized hazelnut extract. J Allergy Clin Immunol. 2005;116:1073-9. Enrique E, Pineda F, Malek T, et al. Sublingual immunotherapy for hazelnut food allergy: A randomized, double-blind, placebo-controlled study with a standardized hazelnut extract. J Allergy Clin Immunol. 2005;116:1073-9.
21.
go back to reference Leung DYM, Sampsom HA, Yunginger JW, et al. Effect of anti-IgE therapy in patients with peanut allergy. N Engl J Med. 2003;348:986-93. Leung DYM, Sampsom HA, Yunginger JW, et al. Effect of anti-IgE therapy in patients with peanut allergy. N Engl J Med. 2003;348:986-93.
Metagegevens
Titel
Immunotherapie op de kinderleeftijd
Auteurs
H. deGroot
E. H. G. vanLeer
Publicatiedatum
01-04-2008
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Tijdschrift voor Kindergeneeskunde / Uitgave 2/2008
Print ISSN: 0376-7442
Elektronisch ISSN: 1875-6840
DOI
https://doi.org/10.1007/BF03078184

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