Skip to main content
Log in

Het placebo-effect in de huisartsenpraktijk: communicatie als medicijn

  • Artikelen
  • Published:
Bijblijven

Samenvatting

Er is groeiend empirisch bewijs dat conditioneringsprocessen, het manipuleren van verwachtingen en de reductie van negatieve gevoelens een placebo- (of nocebo-)effect in werking kunnen zetten. De arts-patiëntcommunicatie biedt mogelijkheden om deze mechanismen te beïnvloeden. Het is voor de effectiviteit van de behandeling van belang dat huisartsen zich bewust zijn van deze mechanismen en de werking ervan proberen in te schatten. Zij kunnen doelgerichte communicatie hierbij op verschillende manieren als instrument gebruiken.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literatuur

  1. Dulmen AM van, Bensing JM. The effect of context in health care: A programming study. RGO, Den Haag, 2001.

    Google Scholar 

  2. Shapiro AK, Shapiro E. The placebo: Is it much ado about nothing? In: Harrington A, editor. The placebo-effect: An interdisciplinary exploration. Cambridge (MA): Harvard University Press, 1997.

    Google Scholar 

  3. Roberts AH, Kewman DG, Mercier L, Hovell M. The power of nonspecific effects in healing: Implications for psychosocial and biological treatments. Clin Psychol Rev 1993;13:375-91.

    Google Scholar 

  4. Wampold BE, Imel ZE, Minami T. The story of placebo effects in medicine: Evidence in context. J Clin Psychol 2007;63:379-90.

    Google Scholar 

  5. Di Blasi Z, Harkness E, Ernst E, Georgiou A, Kleijnen J. Influence of context effects on health outcomes: A systematic review. Lancet 2001;357:757-62.

    Google Scholar 

  6. Benedetti F. How the doctor's words affect the patient's brain. Eval Health Prof 2002;25:369-86.

    Google Scholar 

  7. Colloca L, Lopiano L, Lanotte M, Benedetti F. Overt versus covert treatment for pain, anxiety, and Parkinson's disease. Lancet Neurol 2004;3:679-84.

    Google Scholar 

  8. Myers MG, Cairns JA, Singer J. The consent form as a possible cause of side effects. Clin Pharmacol Ther 1987;42:250-3.

    Google Scholar 

  9. Jewett DL, Fein G, Greenberg MH. A double-blind study of symptom provocation to determine food sensitivity. N Engl J Med 1990;323:429-33.

    Google Scholar 

  10. Lieberman MD, Jarcho JM, Berman S, Naliboff BD, Suyenobu BY, Mandelkern M, et al. The neural correlates of placebo effects: A disruption account. Neuroimage 2004;22:447-55.

    Google Scholar 

  11. Goebel MU, Trebst AE, Steiner J, Xie YF, Exton MS, Frede S, et al. Behavioral conditioning of immunosuppression is possible in humans. FASEB J 2002;16:1869-73.

    Google Scholar 

  12. Crow R, Gage H, Hampson S, Hart J, Kimber A, Thomas H. The role of expectancies in the placebo effect and their use in the delivery of health care: A systematic review. Health Technol Assess 1999;3:1-96.

    CAS  PubMed  Google Scholar 

  13. Levine JD, Gordon NC, Fields HL. The mechanism of placebo analgesia. Lancet 1978;2:654-7.

    Google Scholar 

  14. Petrovic P, Kalso E, Petersson KM, Ingvar M. Placebo and opioid analgesia: Imaging a shared neuronal network. Science 2002;295:1737-40.

    Google Scholar 

  15. Ursin H, Eriksen H. Cognitive activation theory of stress, sensitization, and common health complaints. Ann N Y Acad Sci 2007;1113:304-10.

    Google Scholar 

  16. Cohen S, Frank E, Doyle WJ, Skoner DP, Rabin BS, Gwaltney JM Jr. Types of stressors that increase susceptibility to the common cold in healthy adults. Health Psychol 1998;17:214-23.

    Google Scholar 

  17. Vase L, Robinson ME, Verne GN, Price DD. Increased placebo analgesia over time in irritable bowel syndrome (IBS) patients is associated with desire and expectation but not endogenous opioid mechanisms. Pain 2005;115:338-47.

    Google Scholar 

  18. Pollo A, Vighetti S, Rainero I, Benedetti F. Placebo analgesia and the heart. Pain 2003;102:125-33.

    Google Scholar 

  19. Thomas KB. General practice consultations: Is there any point in being positive? Br Med J (Clin Res Ed) 1987;294:1200-2.

    Google Scholar 

  20. Stewart-Williams S, Podd J. The placebo effect: Dissolving the expectancy versus conditioning debate. Psychological Bulletin 2004;130:324-40.

    Google Scholar 

  21. Barsky AJ, Saintfort R, Rogers MP, Borus JF. Nonspecific medication side effects and the nocebo phenomenon. JAMA 2002;287:622-7.

    Google Scholar 

  22. Hall MA, Dugan E, Zheng B, Mishra AK. Trust in physicians and medical institutions: What is it, can it be measured, and does it matter? Milbank Q 2001;79:613-39.

    Google Scholar 

  23. Ben-Sira, Z. Affective and instrumental components in the physician-patient relationship: An additional dimension of interaction theory. J Health Soc Behav 1980;21:170-80.

    Google Scholar 

  24. Fogarty LA, Curbow BA, Wingard JR, McDonnell K, Somerfield MR. Can 40 seconds of compassion reduce patient anxiety? J Clin Oncol 1999;17:371-9.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

promovendus, Nederlands instituut voor onderzoek van de gezondheidszorg (NIVEL), Utrecht.

directeur Nederlands instituut voor onderzoek van de gezondheidszorg (NIVEL), Utrecht; hoogleraar afdeling Gezondheidspsychologie, Faculteit Sociale Wetenschappen, Universiteit Utrecht.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Verheul, W., Bensing, J.M. Het placebo-effect in de huisartsenpraktijk: communicatie als medicijn. BIJB 24, 38–44 (2008). https://doi.org/10.1007/BF03076330

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03076330

Keywords

Navigation