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Differential outcomes training facilitates memory in people with Korsakoff and Prader-Willi syndromes

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Abstract

This article presents evidence that a teaching procedure called differential outcomes training enhances learning and memory. Differential outcomes training reinforces correct responses with outcomes that are unique and specific to the stimuli that are to be remembered. Teaching with this method enhances performance in people with Korsakoff syndrome and people with Prader-Willi syndrome, populations known to have lerning and working memory deficits. This initial evidence that persons with learning and memory deficits benefit from differential outcomes training should encourage future work on the development of an intervention using this type of training to aide daily functioning by people with learning and memory impairments.

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References

  • American Psychiatric Association. (1994).Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.

    Google Scholar 

  • Biber, C., Butters, N., Rosen, J., Gerstman, L., & Mattis, S. (1981). Encoding strategies and recognition of faces by alcoholic Korsakoff and other brain-damaged patients.Journal of Clinical Neuropsychology, 3, 315–330.

    Article  Google Scholar 

  • Cassidy, S.B. (1984). Prader-Willi syndrome.Current Problems in Pediatrics, 14, 1–55.

    Article  PubMed  Google Scholar 

  • Dricker, J., Butters, N., Berman, G., Samuels, I., & Carey, S. (1978). The recognition and encoding of faces by alcoholic Korsakoff and right hemisphere patients.Neuropsychologia, 16, 683–695.

    Article  PubMed  Google Scholar 

  • Dykens, E.M., Leckman, J.F., & Cassidy, S.B. (1996). Obsessions and compulsions in Prader-Willi syndrome.Journal of Child Psychology and Psychiatry, 37 (8), 995–1002.

    Article  PubMed  Google Scholar 

  • Estévez, A.F., Fuentes, L.J., Mari-Beffa, P., González, C., & Alvarez, D. (2001). The differential outcomes effect as a useful tool to improve conditional discrimination learning in children.Learning and Motivation, 1(32), 48–64.

    Article  Google Scholar 

  • Goeters, S., Blakely, E., & Poling, A. (1992). The differential outcomes effect.Psychological Record, 42, 389–411.

    Google Scholar 

  • Hochhalter, A.K., Sweeney, W.A., Bakke, B.L., Holub, R.J.. & Overmier, J.B. (2000). Improving face recognition in alcohol dementia.Clinical Gerontologist, 22(2), 3–18.

    Article  Google Scholar 

  • Jacobson, R.R., & Lishman, W.A. (1987). Selective memory loss and global intellectual deficits in alcoholic Korsakoff's syndrome.Psychological Medicine, 17, 649–655.

    Article  PubMed  Google Scholar 

  • Joseph, B., Overmier, J.B., & Thompson, T. (1997). Food and nonfood related differential outcomes in equivalence learning by adults with Prader-Willi syndrome.American Journal on Mental Retardation, 101(4), 374–386.

    PubMed  Google Scholar 

  • Joseph, B., Egli, M., Sutcliffe, J.S., & Thompson, T. (2001). Possible dosage effect of maternally expressed genes on visual recognition memory in Prader-Willi syndrome.American Journal of Medical Genetics (Neuropsychiatric Genetics), 105, 71–75.

    Article  Google Scholar 

  • Kopelman, M.D. (1995). The Korsakoff syndrome.British Journal of Psychiatry, 166, 154–173.

    Article  PubMed  Google Scholar 

  • Langlais, P.J. (1995). Alcohol-related thiamine deficiency: Impact on cognitive and memory functioning.Alcohol World, 19 (2), 113–121.

    Google Scholar 

  • Ledbetter, D.H., Mascarello, J.T., Riccardi, V.M., Harper, V.D., Airhard, S.D., & Strobel, R.J. (1982). Chromosome 15 abnormalities and the Prader-Willi syndrome: A follow-up report of 40 cases.American Journal of Human Genetics, 34, 278–285.

    PubMed  Google Scholar 

  • Malanga, P., & Poling, A. (1992). Letter recognition by adults with mental handicaps: Improving performance through differential outcomes.Developmental Disabilities Bulletin, 20(2), 39–48.

    Google Scholar 

  • Mayes, A.R., Downes, J.J., Symons, V., & Shoqeirat, M. (1994). Do amnesics forget faces pathologically fast?Cortex, 30, 543–563.

    PubMed  Google Scholar 

  • Mayes, A.R., Meudell, P., & Neary, D. (1980). Do amnesics adopt inefficient encoding strategies with faces and random shapes?Neuropsychologia, 18, 527–540.

    Article  PubMed  Google Scholar 

  • Oscar-Berman, M., & Bonner, R.T. (1989). Nonmatching-(oddity) and delayed nonmatching-to-sample performance in aging, alcoholic, and alcoholic Korsakoff individuals.Psychobiology, 17, 424–430.

    Google Scholar 

  • Savage, L.M., & Langlais, P.J. (1995). Differential outcomes attenuates spatial memory impairments seen in pyrithiamine-induced thiamine deficient rats.Psychobiology, 23, 153–160.

    Google Scholar 

  • Savage, L.M., & Parsons, J. (1997). The effects of delay interval, intertrial interval, amnestic drugs, and differential outcomes on matching-to-position in rats.Psychobiology, 25(4), 303–312.

    Google Scholar 

  • Savage, L.M., Pitkin, S.R., & Careri, J.M. (1999). Memory enhancement in aged rats: The differential outcomes effect.Developmental Psychobiology, 35(4), 318–327.

    Article  PubMed  Google Scholar 

  • Savage, L.M., Pitkin, S., & Knitowski, K. (1999). Rats exposed to pyrithiamine—induced thiamine deficiency are more sensitive to the amnestic effects of scopolamine and MK-801: Examination of working memory, response selection, and reinforcement contingencies.Behavioural Brain Research, 104, 13–26.

    Article  PubMed  Google Scholar 

  • Savage, L.M., Stanchfield, M.A., & Overmier, J.B. (1994). The effects of scopolamine, diazepam, and lorazepam on working memory in pigeons: An analysis of reinforcement procedures and sample problem type.Pharmacology Biochemistry and Behavior, 48(1), 183–191.

    Article  Google Scholar 

  • Sidman, M. (1997). Equivalence relations.Journal of the Experimental Analysis of Behavior, 68(2), 258–266

    Article  PubMed  Google Scholar 

  • Trapold, M.A. (1970). Are expectancies based upon different positive reinforcing events discriminably different?Learning and Motivation, 1, 129–140.

    Article  Google Scholar 

  • Trapold, M.A., & Overmier, J.B. (1972). The second learning process in instrumental learning. In A.H. Black & W.F. Prokasy (Eds.),Classical Conditioning II: Current Theory and Research (pp. 427–452). New York: Appleton-Century-Crofts.

    Google Scholar 

  • Vietor, M., Adams, R.D., & Collins, G.H..The Wernicke-Korsakoff Syndrome and Related Neurologic Disorders to Alcoholism and Malnutrition. 1989. Philadelphia: F.A. Davis.

    Google Scholar 

  • Warren, J.L., & Hunt, E. (1981). Cognitive processing in children with Prader-Willi syndrome. In V.A. Holm, S. Sulzbacher & P. Pipes (Eds.),The Prader-Willi syndrome (pp. 161–178). Baltimore: University Park Press.

    Google Scholar 

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Correspondence to Angela K. Hochhalter.

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Hochhalter, A.K., Joseph, B. Differential outcomes training facilitates memory in people with Korsakoff and Prader-Willi syndromes. Integr. psych. behav. 36, 196–204 (2001). https://doi.org/10.1007/BF02734093

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