Skip to main content
Log in

Empirically derived subtypes of pervasive developmental disorders: A cluster analytic study

  • Published:
Journal of Autism and Developmental Disorders Aims and scope Submit manuscript

Abstract

A cluster analytic study was conducted to empirically derive behaviorally homogeneous subtypes of pervasive developmental disorders (PDD). Subjects were clustered based on a broad range of behavioral symptoms which characterize autism. Behavioral variables were measured using several of the standardized psychometric instruments most commonly employed in assessing autistic individuals. The cluster solution indicated the presence of four distinct groups. Validity checks generally confirmed significant between-group differences on independent measures of social, language, and stereotyped behaviors. In addition, the four-group cluster solution was compared to previously developed typological systems of PDD (i.e., subcategories based on IQ, early onset, styles of social interaction, and DSM-III-R diagnosis). Results generally supported both the behavioral homogeneity of the four subgroups and also several important between-group differences. The potential utility of using cluster analyses to explore subtypes of PDD is discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Aldenderfer, M. S., & Blashfield, R. K. (1984).Cluster analysis. Beverly Hills: Sage.

    Google Scholar 

  • Aman, M. G., & Kern, R. A. (1989). Review of fenfluramine in the treatment of developmental disabilities.Journal of the American Academy of Child and Adolescent Psychiatry, 28, 549–565.

    Google Scholar 

  • American Psychiatric Association (1980).Diagnostic and statistical manual of mental disorders (3rd ed.). Washington, DC: Author.

    Google Scholar 

  • American Psychiatric Association. (1987).Diagnostic and statistical manual of mental disorders (3rd ed., rev.). Washington, DC: Author.

    Google Scholar 

  • August, G. J., Raz, N., & Baird, T. D. (1985). Brief report: Effects of fenfluramine on behavioral, cognitive, and affective disturbances in autistic children.Journal of Autism and Developmental Disorders, 15, 97–105.

    Google Scholar 

  • August, G. J., Raz, N., & Baird, T. D. (1987). Fenfluramine response in high and low functioning autistic children.Journal of the American Academy of Child and Adolescent Psychiatry, 26, 342–346.

    Google Scholar 

  • Beale, E. M. L. (1969).Cluster analysis. London: Scientific Control Systems.

    Google Scholar 

  • Borgen, F. H., & Barnett, D. C. (1987). Applying cluster analysis in counseling psychology research.Journal of Counseling Psychology, 34, 456–468.

    Google Scholar 

  • Comrey, A. L. (1985). A method for removing outliers to improve factor analytic results.Multivariate Behavioral Research, 20, 273–281.

    Google Scholar 

  • Freeman, B. J., Ritvo, E. R., Yokota, A., & Ritvo, A. (1986). A scale for rating symptoms of patients with the syndrome of autism in real life settings.Journal of the American Academy of Child and Adolescent Psychiatry, 25, 130–136.

    Google Scholar 

  • Garfin, D. G., McCallon, D., & Cox, R. (1988). Validity and reliability of the Childhood Autism Rating Scale with autistic adolescents.Journal of Autism and Developmental Disorders, 18, 367–378.

    Google Scholar 

  • Grossman, H. J. (1983).Classification in mental retardation. Washington, DC: American Association on Mental Retardation.

    Google Scholar 

  • Hertzig, M. E., Snow, M. E., New, E., & Shapiro, T. (1990). DSM-III and DSM-III-R diagnosis of autism and pervasive developmental disorder in nursery school children.Journal of the American Academy of Child and Adolescent Psychiatry, 29, 123–126.

    Google Scholar 

  • Krug, D. A., Arick, J., & Almond, P. (1980). Behavior checklist for identifying severely handicapped individuals with high levels of autistic behavior.Journal of Child Psychology and Psychiatry, 21, 221–229.

    Google Scholar 

  • Lambert, N., Windmiller, M., Thoringer, D., & Cole, L. J. (1975).AAMD Adaptive Behavior Scale (rev. ed.). Washington, DC: American Association on Mental Retardation.

    Google Scholar 

  • Lorr, M. (1983).Cluster analysis for the social sciences. San Francisco: Jossey-Bass.

    Google Scholar 

  • Matson, J. L. (1988).Treating childhood and adolescent psychopathology: A handbook. New York: Plenum Press.

    Google Scholar 

  • Matson, J. L. (1989).Chronic schizophrenia and adult autism: Issues in diagnosis, assessment and treatment. New York: Springer.

    Google Scholar 

  • Matson, J. L., & Mulick, J. A. (1991).Handbook of mental retardation (2nd ed.). New York: Pergamon.

    Google Scholar 

  • Mesibov, G. B., Schopler, E., Schaffer, B., & Michal, N. (1989). Use of the Childhood Autism Rating Scale with autistic adolescents and adults.Journal of the American Academy of Child and Adolescent Psychiatry, 28, 538–541.

    Google Scholar 

  • Milligan, G. W., & Cooper, M. C. (1985). An examination of procedures for determining the number of clusters in a data set.Psychometrika, 50, 159–179.

    Google Scholar 

  • Perry, A., & Factor, D. C. (1989). Psychometric validity and clinical usefulness of the Vineland Adaptive Behavior Scales and the AAMD Adaptive Behavior Scale for an autistic sample.Journal of Autism and Developmental Disorders, 19, 41–55.

    Google Scholar 

  • Pomeroy, J. C., Friedman, C., & Stephens, L. (1991). Autism and Asperger's: Same or different?Journal of the American Academy of Child and Adolescent Psychiatry, 29, 152.

    Google Scholar 

  • Rescorla, L. (1988). Cluster analytic identification of autistic preschoolers.Journal of Autism and Developmental Disorders, 18, 475–492.

    Google Scholar 

  • Ritvo, E. R., & Freeman, B. J. (1978). National Society for Autistic Children Definition of the Syndrome of Autism.Journal of Autism and Developmental Disorders, 8, 162–170.

    Google Scholar 

  • Ritvo, E. R., Freeman, B. J., Geller, E., & Yuwiler, A. (1983). Effects of fenfluramine on 14 outpatients with the syndrome of autism.Journal of the American Academy of Child and Adolescent Psychiatry, 22, 549–558.

    Google Scholar 

  • Ritvo, E. R., Freeman, B. J., Geller, E., Yokota, A., Schroth, P., & Novak, P. (1984). Study of fenfluramine in outpatients with the syndrome of autism.Journal of Pediatrics, 105, 823–828.

    Google Scholar 

  • Rogers, S. J., & DiLalla, D. L. (1990). Age of symptom onset in young children with pervasive developmental disorders.Journal of the American Academy of Child and Adolescent Psychiatry, 29, 863–872.

    Google Scholar 

  • Romesburg, H. C. (1984).Cluster analysis for researchers. Belmont, CA: Lifetime Learning.

    Google Scholar 

  • Rutter, M. (1978). Diagnosis and definition of childhood autism.Journal of Autism and Developmental Disorders, 8, 139–161.

    Google Scholar 

  • Rutter, M., & Garmezy, N. (1983). Developmental psychopathology. In E. M. Hetherington (Ed.),Handbook of child psychology (Vol. 4). New York: Wiley.

    Google Scholar 

  • Rutter, M., & Schopler, E. (1992). Classification of pervasive developmental disorders: Some concepts and practical considerations.Journal of Autism and Developmental Disorders, 22, 459–482.

    Google Scholar 

  • Sarle, W. S. (1983).The cubic clustering criterion. (Technical Report A-108.) Cary, NC: SAS Institute.

    Google Scholar 

  • SAS Institute Inc. (1988).SAS/STAT User's Guide, Release 6.03 Edition. Cary, NC: Author.

    Google Scholar 

  • Sattler, J. M. (1988).Assessment of children. San Diego: Author.

    Google Scholar 

  • Schopler, E. (1978). On confusion in the diagnosis of autism.Journal of Autism and Developmental Disorders, 8, 137–138.

    Google Scholar 

  • Schopler, E., Reichler, R. J., Devellis, R. F., & Daly, K. (1980). Toward objective classification of childhood autism: Childhood Autism Rating Scale (CARS).Journal of Autism and Developmental Disorders, 10, 91–103.

    Google Scholar 

  • Schopler, E., Reichler, R. J., & Renner, B. R. (1988).The Childhood Autism Rating Scale. Los Angeles: Western Psychological Services.

    Google Scholar 

  • Schreibman, L., & Mills, J. I. (1983). Infantile autism. In T. A. Ollendick & M. Hersen (Eds.),Handbook of child psychopathology. New York: Plenum Press.

    Google Scholar 

  • Sevin, J. A., Matson, J. L., Coe, D. A., Fee, V. E., & Sevin, B. M. (1991). A comparison and evaluation of three commonly used autism scales.Journal of Autism and Developmental Disorders, 21, 417–432.

    Google Scholar 

  • Siegel, B., Anders, T. F., Ciaranello, R. D., Bienenstock, B., & Kraemer, H. C. (1986). Empirically derived subclassification of the autistic syndrome.Journal of Autism and Developmental Disorders, 16, 275–293.

    Google Scholar 

  • Siegel, B., Vukicevic, J., Elliot, G. R., & Kraemer, H. C. (1989). The use of signal detection theory to assess DSM-III-R criteria for autistic disorder.Journal of the American Academy of Child and Adolescent Psychiatry, 28, 542–548.

    Google Scholar 

  • Sparrow, S. S., Balla, D. A., & Cicchetti, D. V. (1984). TheVineland Adaptive Behavior Scales. Minneapolis, MN: American Guidance Service.

    Google Scholar 

  • Spitzer, R. L., & Siegel, B. (1990). The DSM-III-R field trial of pervasive developmental disorders.Journal of the American Academy of Child and Adolescent Psychiatry, 29, 855–862.

    Google Scholar 

  • Szatmari, P. (1989).Literature review on the DSM-III-R criteria for autistic disorder. Report to the DSM-IV committee.

  • Szatmari, P., Tuff, L., Finlayson, A. J., & Bartolucci, G. (1990). Asperger's syndrome and autism: Neurocognitive aspects.Journal of the American Academy of Child and Adolescent Psychiatry, 29, 130–136.

    Google Scholar 

  • Tager-Flusberg, H., Calkins, S., Nolin, T., Baumberger, T., Anderson, M., & Chadwick-Dias, A. (1990). A longitudinal study of language in autistic and Down syndrome children.Journal of Autism and Developmental Disorders, 20, 1–22.

    Google Scholar 

  • Volkmar, F. (1987). Diagnostic issues in the pervasive developmental disorders.Journal of Child Psychology and Psychiatry, 28, 365–369.

    Google Scholar 

  • Volkmar, F., Cicchetti, D. V., Dykens, E., Sparrow, S. S., Leckman, J. F., & Cohen, D. J. (1988). An evaluation of the Autism Behavior Checklist.Journal of Autism and Developmental Disorders, 18, 81–97.

    Google Scholar 

  • Volkmar, F., Cohen, D. J., Bregman, J. D., Hooks, M. Y., & Stevenson, J. M. (1989). An examination of social typologies in autism.Journal of the American Academy of Child and Adolescent Psychiatry, 28, 82–86.

    Google Scholar 

  • Volkmar, F., Sparrow, S. S., Goudreau, D., Cicchetti, D. V., Paul, R., & Cohen, D. J. (1987). Social deficits in autism: An operational approach using the Vineland Adaptive Behavior Scales.Journal of the American Academy of Child and Adolescent Psychiatry, 26, 156–161.

    Google Scholar 

  • Ward, J. H. (1963). Hierarchical grouping to optimize an objective function.Journal of the American Statistical Association, 58, 236–244.

    Google Scholar 

  • Wing, L., & Arwood, A. (1987). Syndromes of autism and atypical development. In D. J. Cohen & A. Donnelan (Eds.),Handbook of autism. New York: Wiley.

    Google Scholar 

  • Wing, L., & Gould, J. (1979). Severe impairments of social interaction and associated abnormalities in children: Epidemiology and classification.Journal of Autism and Developmental Disorders, 9, 11–29.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sevin, J.A., Matson, J.L., Coe, D. et al. Empirically derived subtypes of pervasive developmental disorders: A cluster analytic study. J Autism Dev Disord 25, 561–578 (1995). https://doi.org/10.1007/BF02178188

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02178188

Keywords

Navigation