Skip to main content
SpringerLink
Log in

Brief report: Duplication of chromosome 15q11-13 in two individuals with autistic disorder

  • Brief Reports
  • Published:
Journal of Autism and Developmental Disorders Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • American Psychiatric Association. (1987).Diagnostic and statistical manual of mental disorders, (3rd ed., rev.). Washington, DC: Author.

    Google Scholar 

  • Cohen, I. L., Sudhalter, V., Pfadt, A., Jenkins, E. C., Brown, W. T., & Vietze, P. M. (1991). Why are autism and the fragile-X syndrome associated? Conceptual and methodological issues.American Journal of Human Genetics, 48, 195–202.

    Google Scholar 

  • Elliot, G. R., & Ciaranello, R. D. (1987). Neurochemical hypotheses of childhood psychoses. In E. Schopler & G. Mesibov (Eds.),Neurobiological issues in autism. New York: Plenum Press.

    Google Scholar 

  • Folstein, S. E., & Piven, J. (1991). Etiology of autism: genetic influences.Pediatrics, 87, 767–773.

    Google Scholar 

  • Gillberg, C., Steffenburg, S., Walhstrom, J., Gillberg, I. C., Sjostedt, A., Martinsson, T., Liedgren, S., & Eeg-Olofsson, O. (1991). Autism associated with marker chromosome.Journal of the American Academy of Child and Adolescent Psychiatry, 30, 489–494.

    Google Scholar 

  • Ledbetter, D. H., Riccardi, V. M., Airhart, S. D., Strobel R. J., Keenan, S. B., & Crawford, J. D. (1981). Deletions of chromosome 15 as a cause of the Prader-Willi Syndrome.New England Journal of Medicine, 304, 325–329.

    Google Scholar 

  • Ledbetter, D. H., Mascarello, J. T., Riccardi, V. M., Harper, V. D., Airhart, S. D., & Strobel, R. J. (1982). Chromosome 15 abnormalities and the Prader-Willi Syndrome.American Journal of Human Genetics, 34, 278–285.

    Google Scholar 

  • Lupski, J. R., Wise, C. A., Kuwano, A., Pentao, L., Parke, J. T., Glaze, D. G., Ledbetter, D. H., Greenberg, F., & Patel, P. I. (1992). Gene dosage is a mechanism for Charcot-Marie-Tooth disease type 1A.Nature Genetics, 1, 29–33.

    Google Scholar 

  • Piven, J., Gayle, J., Landa, R., Wzorek, M., & Folstein, S. (1991). The prevalence of fragile X in a sample of autistic individuals diagnosed using a standardized interview.Journal of the American Academy of Child and Adolescent Psychiatry, 30, 825–830.

    Google Scholar 

  • Robinson, W. P., Binkert, F., Gine, R., Vazquez, C., Muller, W., Rosenkrantz, N., & Schinzel, A. (1993). Clinical and molecular analysis of five inv dup (15) patients.European Journal of Human Genetics, 1, 37–50.

    Google Scholar 

  • Schinzel, A. (1981). Particular behavioral symptomatology in patients with rarer autosomal chromosome aberrations. In Schmid W., Nielsen J. (ed): “Human Behavior and Genetics”. Amsterdam: Elsevier/North Holland.

    Google Scholar 

  • Wagstaff, J., Knoll, J. H. M., Fleming, J., Kirkness, E. F., Martin-Gallardo, A., Greenberg, F., Graham, J. M., Menninger, J., Ward, D., Venter, J. C., & Lalande, M. (1991). Localization of the gene encoding the GABA-A receptor β3 subunit to the Angelman/Prader-Willi region of human chromosome 15.American Journal of Human Genetics, 49, 330–337.

    Google Scholar 

  • Wisniewski, L., Hassold, T., Heffelfinger, J., & Higgins, J. V., (1979). Cytogenetic and clinical studies in five cases of inv dup(15).Human Genetics, 50, 259–270.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Psychiatry, University of Iowa College of Medicine, USA

    Peggy Baker & Joseph Piven

  2. Center for Human Genetics, Case Western Reserve University, USA

    Stuart Schwartz

  3. Department of Pediatrics, University of Iowa College of Medicine, USA

    Shiva Patil

Authors
  1. Peggy Baker
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Joseph Piven
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Stuart Schwartz
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Shiva Patil
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Work on this paper was supported in part by NIMH grant MH-01028-02 to Dr. Piven. We thank Denis Hulseberg for performing FISH studies on Case 1.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Baker, P., Piven, J., Schwartz, S. et al. Brief report: Duplication of chromosome 15q11-13 in two individuals with autistic disorder. J Autism Dev Disord 24, 529–535 (1994). https://doi.org/10.1007/BF02172133

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02172133

Keywords

Search

Navigation