Conclusion
The behavioral and/or psychiatric symptoms in autistic people as described above have been viewed by many professionals dealing with autistic populations as “associated features of autism” that may result from these individuals' inability to cope with the environmental demands and physical discomfort. Traditionally, in treating individuals with autism, special education intervention including behavioral modifications has been the main emphasis. Such an approach has made some progress in milder and uncomplicated cases of autism. However, if many of these behavioral and/or psychiatric symptoms in those with more severe associated features can be viewed as symptoms of various comorbid psychiatric disorders, there are data suggesting that with an appropriate evaluation, predrug workups, a specific diagnosis, and multiple measures of outcome, pharmacotherapy can be a safe and efficacious adjunct treatment for some symptoms in autistic persons. Nevertheless, the data presented here were obtained mainly from autistic children. A great deal of work remains to be done Future research should put more emphasis on developing agreeable, reliable, and valid diagnostic instruments for identifying comorbid psychiatric disorders in autistic people. Future research should also emphasize employing a randomized double-blind placebo-controlled crossover design, as well as involving multicenters and using uniformed diagnostic criteria to study autistic adolescents and adults.
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References
Ando, H., & Yoshimura, I. (1979). Effects of age on communication skill levels and prevalence of maladaptive behaviors in autistic and mentally retarded children.Journal of Autism and Development Disorders, 9, 83–93.
Barabas, G., & Matthews, W. S. (1983). Coincident infantile autism and Tourette syndrome: A case report.Journal of Autism and Developmental Disorders, 13, 280–281.
Chung, S. Y., Luk, S. L., & Lee, P. W. H. (1990). A follow-up study of Infantile Autism in Hong Kong.Journal of Autism and Developmental Disorders, 20, 221–232.
Clarke, D. J., Littlejohns, C. S., Corbett, J. A., & Joseph, S. (1989). Pervasive developmental disorders and psychosis in adult life.British Journal of Psychiatry, 155, 692–699.
Comings, D. E., & Comings, B. G. (1991). Clinical and genetic relationship between autism-pervasive developmental disorder and Tourette syndrome: A study of 19 cases.American Journal of Medical Genetics, 39, 180–191.
Fombonne, E. (1992). Diagnostic assessment in a sample of autistic and developmentally impaired adolescents.Journal of Autism and Developmental Disorders, 22, 563–581.
Ghaziuddin, M., & Tsai, L. (1991). Depression in autistic disorder.British Journal of Psychiatry, 159, 721–723.
Ghaziuddin, M., Tsai, L., & Alessi, N. (1992). ADHD and PDD.Journal of the American Academy of Child and Adolescent Psychiatry, 31, 567.
Gillberg, C. (1985). Asperger's syndrome and recurrent psychosis—A case study.Journal of Autism and Developmental Disorders, 15, 389–397.
Komoto, J., Usui, S., & Hirata, J. (1984). Infantile autism and affective disorder.Journal of Autism and Developmental Disorders, 14, 81–84.
Lainhart, J. E., & Folstein, S. E. (1994). Affective Disorders in people with Autism: A review of published cases.Journal of Autism and Developmental Disorders, 24, 587–601.
Le Couteur, A., Rutter, M., Lord, C., Rios, P., Robertson, S., Holdgrafer, M., & McLennan, J. (1989). Autism Diagnostic Interview: A standardized investigator-based instrument.Journal of Autism and Developmental Disorders, 19, 363–387.
McDougle, C. J., Price, L. H., & Goodman, W. K. (1990). Fluvoxamine treatment of coincident Autistic Disorder and Obsessive-Compulsive Disorder: A case report.Journal of Autism and Developmental Disorders, 20, 537–543.
Petty, L. K. Ornitz, E. M., Michelman, J. D., & Zimmerman, E. G. (1984). Autistic children who become schizophrenic.Archives of General Psychiatry, 41, 129–135.
Realmuto, G. M., & Main, B. (1982). Coincidence of Tourett's disorder and infantile autism.Journal of Autism and Developmental Disorders, 12, 367–372.
Rumsey, J. M., Rapoport, J. L., & Sceery, W. R. (1985). Autistic children as adults: Psychiatric, social, and behavioral outcomes.Journal of the American Academy of Child Psychiatry, 24, 465–473.
Rutter, M., Greenfeld, D., & Lockyer, L. (1967). A five to fifteen year follow-up study of Infantile Psychosis: II. Social and behavioral outcome.British Journal of Psychiatry, 113, 1183–1199.
Simons, J. M. (1974). Observations on compulsive behavior in autism.Journal of Autism and Childhood Schizophrenia, 4, 1–10.
Steingard, R., & Biederman, J. (1987). Lithium responsive manic-like symptoms in two individuals with autism and mental retardation.Journal of American Academy of Child Adolescent Psychiatry, 26, 932–935.
Sverd, J., Montera, G., & Gurevich, N. (1993). Cases for an association between Tourette syndrome, Autistic Disorder, and Schizophrenia-Like Disorder.Journal of Autism and Developmental Disorder, 23, 407–413.
Tsai, L. (1992). Diagnostic issues in high-functioning autism. In E. Schopler & G. B. Mesibov (Eds.),High-functioning individuals with autism (pp. 11–40). New York: Plenum Press.
Tsai, L. (1994).Comorbid disorders of autistic disorder. Presented at the Special Interest Group of Annual Meeting of American Academy of Child and Adolescent Psychiatry, New York City.
Volkmar, F. R., & Cohen, D. J. (1991). Comorbid association of autism and schizophrenia.American Journal of Psychiatry, 148, 1705–1707.
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Tsai, L.Y. Brief report: Comorbid psychiatric disorders of autistic disorder. J Autism Dev Disord 26, 159–163 (1996). https://doi.org/10.1007/BF02172004
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DOI: https://doi.org/10.1007/BF02172004