Skip to main content
Log in

Pain agnosia and self-injury in the syndrome of reversible somatotropin deficiency (psychosocial dwarfism)

  • Published:
Journal of autism and childhood schizophrenia Aims and scope Submit manuscript

Abstract

Hospital and social service records of 32 patients, 23 boys and 9 girls, with reversible behavioral symptoms in a syndrome of dwarfism characterized by reversible inhibition of growth in stature are surveyed and discussed. When first seen, the patients ranged in age from 22 months to 16 years and 2 months. After initial hospitalization, they were discharged to a convalescent home and then to foster homes to experience a prolonged change of domicile and thus continue to grow. Changes in domicile from adverse environments, where growth failure began and persisted, to ameliorative where catch-up growth took place covaried significantly (p<.001) with decreased incidence of physical injury, severe physical punishment or abuse, self-inflicted injury, and behavior indicating pain agnosia. It is suggested that self-injury may counteract cognitional starvation under conditions of sensory deprivation when self-inflicted injury and pain agnosia coexist.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Beçak, W., Beçak, M. L., & Schmidt, B. J. Chromosomal trisomy of group 13–15 in two cases of generalized congenital analgesia.Lancet, 1963,1, 664–665.

    PubMed  Google Scholar 

  • Bowlby, J. Maternal care and mental health. Geneva:World Health Organization Monograph Series, 1952.

  • Capitanio, M. A., & Kirkpatrick, J. A. Widening of the cranial sutures. A roentgen observation during periods of accelerated growth in patients treated for deprivation dwarfism.Radiology, 1969,92, 53–59.

    PubMed  Google Scholar 

  • Critchley, M. Congenital indifference to pain.Annals of Internal Medicine, 1956,45, 737–747.

    PubMed  Google Scholar 

  • Ford, F. R., & Wilkins, L. Congenital universal indifference to pain.Bulletin of The Johns Hopkins Hospital, 1938,62, 448–466.

    Google Scholar 

  • Freedman, D. A. The role of early mother/child relations in the etiology of some cases of mental retardation. In G. Farrell (Ed.),Advances in mental science. I: Congenital mental retardation. Austin: University of Texas Press, 1969.

    Google Scholar 

  • Harlow, H. F. The development of affectional patterns in infant monkeys. In B. M. Foss (Ed.),Determinants of infant behavior. London: Methuen, 1961.

    Google Scholar 

  • Harlow, H. F. Early social deprivation and later behavior in the monkey. In A. Abrams, H. Garner, & J. Toman (Eds.),Unfinished tasks in the behavioral sciences. Baltimore: Williams & Wilkins, 1964.

    Google Scholar 

  • Harlow, H. F., & Suomi, S. J. Induced psychopathology in monkeys.Engineering and Science, 1970,33, 8–14.

    Google Scholar 

  • Marchand, W. E. Occurrence of painless myocardial infarction in psychotic patients.New England Journal of Medicine, 1955,253, 51–55.

    PubMed  Google Scholar 

  • Marchand, W. E. Occurrence of painless acute surgical disorders in psychotic patients.New England Journal of Medicine, 1959,260, 580–585.

    PubMed  Google Scholar 

  • Martschenko, A. T. Die Waechter schaemen sich. (Trans.: The guards are embarrassed.)Der Spiegel, 1969,23, 140–153.

    Google Scholar 

  • Melzack, R. Early experience: A neuropsychological approach to heredity-environment interactions. In G. Newton & S. Levine (Eds.),Early experience and behavior. Springfield, Ill.: Charles C Thomas, 1968.

    Google Scholar 

  • Miller, R. E., Mirsky, I. A., Caul, W. F., & Sakata, T. Hyperphagia and polydipsia in socially isolated rhesus monkeys.Science, 1969,165, 1027–1028.

    PubMed  Google Scholar 

  • Nyhan, W. L. A disorder of uric acid metabolism and cerebral function in childhood.Arthritis and Rheumatism, 1965,8, 659–664.

    PubMed  Google Scholar 

  • Ogden, T. E., Robert, F., & Carmichael, E. A. Some sensory syndromes in children: Indifference to pain and sensory neuropathy.Journal of Neurology, Neurosurgery and Psychiatry, 1959,22, 267–276.

    Google Scholar 

  • Patton, R. G., & Gardner, L. I. Influence of family environment on growth: The syndrome of “maternal deprivation”.Pediatrics, 1962,30, 957–962.

    Google Scholar 

  • Patton, R. G., & Gardner, L. I.Growth failure in maternal deprivation. Springfield, Ill.: Charles C Thomas, 1963.

    Google Scholar 

  • Patton, R. G., & Gardner, L. I. Short stature associated with maternal deprivation syndrome: Disordered family environment as cause of so-called idiopathic hypopituitarism. In L. I. Gardner (Ed.),Endocrine and genetic diseases of childhood. Philadelphia: Saunders, 1969.

    Google Scholar 

  • Petrie, A.Individuality in pain and suffering. Chicago: University of Chicago Press, 1967.

    Google Scholar 

  • Powell, G. F., Brasel, J. A., & Blizzard, R. M. Emotional deprivation and growth retardation simulating idiopathic hypopituitarism.New England Journal of Medicine, 1967,276, 1271–1278.

    PubMed  Google Scholar 

  • Powell, G. F., Brasel, J. A., Raiti, S., & Blizzard, R. M. Emotional deprivation and growth retardation simulating idiopathic hypopituitarism. II. Endocrinologic evaluation of the syndrome.New England Journal of Medicine, 1967,276, 1279–1283.

    PubMed  Google Scholar 

  • Reinhart, J. B., & Drash, A. L. Psychosocial dwarfism: Environmentally induced recovery.Psychosomatic Medicine, 1969,31, 165–172.

    PubMed  Google Scholar 

  • Silver, H. K., & Finkelstein, M. Deprivation dwarfism.Pediatrics, 1967,70, 317–324.

    Google Scholar 

  • Spitz, R. A. Hospitalism.Psychoanalytic Study of the Child, 1945,1, 53–74.

    Google Scholar 

  • Spitz, R. A., & Wolf, K. M. Anaclitic depression.Psychoanalytic Study of the Child, 1946,2, 313–342.

    Google Scholar 

  • Wolff, G., & Money, J. Relationship between sleep and growth in patients with reversible somatotropin deficiency (psychosocial dwarfism).Psychological Medicine, 1972, in press.

Download references

Author information

Authors and Affiliations

Authors

Additional information

This study was supported by a grant from the Erickson Educational Foundation and by USPHS grants HD 18635, HD 00325, HD 01852 and RR 00035 (GCRCP).

The patients in this sample were diagnosed and managed under the supervision of Dr. Robert M. Blizzard. The clinical cooperation of members of the pediatric endocrine clinic and the availability of its medical files are greatly appreciated. Dr. Robert Athanasiou assisted with the statistical reduction of the data. We also thank the staff at Happy Hills Hospital for their excellent cooperation.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Money, J., Wolff, G. & Annecillo, C. Pain agnosia and self-injury in the syndrome of reversible somatotropin deficiency (psychosocial dwarfism). J Autism Dev Disord 2, 127–139 (1972). https://doi.org/10.1007/BF01537566

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01537566

Keywords

Navigation