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The genetic analysis of repeated measures. I. Simplex models

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Abstract

The well-known simplex model is extended to a model that may be used for the genetic and environmental analysis of covariance structures. This “double” simplex structure can be specified as a LISREL model. It is shown that data which give rise to a simplex correlation structure, such as repeated-measures data, do not fit a factor-analysis model. The parameter estimation of the simplex model is illustrated with computer-simulated twin data.

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Boomsma, D.I., Molenaar, P.C.M. The genetic analysis of repeated measures. I. Simplex models. Behav Genet 17, 111–123 (1987). https://doi.org/10.1007/BF01065991

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  • DOI: https://doi.org/10.1007/BF01065991

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