Abstract
Renal failure in the newborn infant is mainly determined by vascular causes. In this report we describe a patient with a particular vascular cause of renal failure. The patients was the product of a twin pregnancy in which the twin partner died in utero. In retrospect, the twins appeared to be monozygotic. As the pregnancy was studied carefully prenatally by ultrasound, we were able to observe the development of this condition, characterized by oliguria, oligohydramnios, and lung hypoplasia; the oligohydramnios sequence. After organ development had been normal initially, renal function was lost and the oligohydramnios sequence developed in the survivor after the cotwin had died in utero.
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References
Stapleton FB, Jones DP, Green RS (1987) Acute renal failure in neonates: incidence, actiology and outcome. Pediatr Nephrol 1: 314–320
D'Alton M, Mercer B, Riddick E, Dudley D (1992) Serial thoracic versus abdominal circumference ratios for the prediction of pulmonary hypolasia in premature rupture of the membranes remote from term. Am J Obstet Gynecol 166: 658–663
Reisman LE, Pathak A (1966) Bilateral renal cortical necrosis in the newborn. Am J Dis Child 111: 541–543
Moore CM, McAdams AJ, Sutherland J (1969) Intrauterine disiminated intravascular coagulation: a syndrome of multiple pregnancy with a dead twin fetus. J Pediatr 74: 523–528
Stark H, Geiger R (1973) Renal tubular dysfunction following vascular accidents of the kidneys in the newborn period. J Pediatr 83: 933–940
Gosseye S, Golaire MC, Larroche JC (1982) Cerebral, renal and splenic lesions due to fetal anoxia and their relationship to malformations. Dev Med Child Neurol 24: 510–518
Szymonowicz W, Preston H, Yu VYH (1986) The surviving monozygotic twin. Arch Dis Child 61: 454–458
Larroche JCl, Droullé P, Delezoide AL, Narcy F, Nessmann C (1990) Brain damage in monozygous twins. Biol Neonate 57: 261–278
Fusi I, Gordon H (1990) Twin pregnancy complicated by single intrauterine death. Problems and outcome with conservative management. Br J Obstet Gynaecol 97: 511–516
Schinzel AGL, Smith DW, Miller JR (1979) Monzygotic twinning and structural defects. J Pediatr 95: 921–930
Scheller JM, Nelson KB (1992) Twinning and neurologic morbidity. Am J Dis Child 146: 1110–1113
Benirschke K (1961) Twin placenta in perinatal mortality. NY State J Med 61: 1499–1508
Enbom JA (1985) Twin pregnancy with intrauterine death of one twin. Am J Obstet Gynecol 152: 424–429
Larroche JCl (1986) Fetal encephlopathies of circulatory origin. Biol Neonate 50: 61–74
Anderson RL, Golbus MS, Curry CJR, Callen PW, Hastrup WH (1990) Central nervous system damage and other anomalies in surviving fetus following second trimester antenatal death of cotwin. Prenat Diagn 10: 513–518
Mannino FL, Lyons Jones K, Benirschke K (1977) Congenital skin defects and fetus papyraceus. J Pediatr 91: 559–564
Hughes HE, Miskin M (1986) Congenital microcephaly due to vascular disruption: in utero documentation. Pediatrics 78: 85–97
Jung JH, Graham JM, Schultz N, Smith DW (1984) Congenital hydranencephaly/prorencephaly due to vascular disruption in monozygotic twins. Pediatrics 73: 467–469
Hoyme HE, Higginbottom MC, Jones KL (1981) Vascular etiology of disruptive structural defects in monozygotic twins. Pediatrics 67: 288–291
Yoshioka H, Kadamoto Y, Mino M, Morikawa Y, Kasubuchi Y, Kusunoki T (1979) Multicystic encephalomalacia in liverborn twin with a stillborn macerated co-twin. J Pediatr 79: 798–800
Melnick M (1977) Brain damage in survivor after in-utero death of monozygous co-twin. Lancet II: 1287
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van Heijst, A.F.J., Nijhuis, J.G., Bult, P. et al. Renal failure in the surviving monochorionic twin after death of the co-twin in utero. Pediatr Nephrol 10, 51–54 (1996). https://doi.org/10.1007/BF00863443
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DOI: https://doi.org/10.1007/BF00863443