Skip to main content
Log in

A comparison of clinical and research DSM-III-R diagnoses of schizophrenia in a Finnish national birth cohort

Clinical and research diagnoses of schizophrenia

  • Original Paper
  • Published:
Social Psychiatry and Psychiatric Epidemiology Aims and scope Submit manuscript

Abstract

As a prerequisite to the use of the Finnish National Hospital Discharge Register in psychiatric epidemiological research, we studied the diagnostic reliability of the register in terms of the psychiatric morbidity experienced by a national birth cohort. We investigated all entries to the register for a sample based upon the Northern Finland 1966 birth cohort at the age of 16 years (n=11017). Until the end of 1993 (age 27 years), a total of 563 subjects had a register diagnosis indicating a psychiatric illness, 37 of them being schizophrenia. When operational criteria (DSM-III-R) were applied to clinical information in the available original hospital records for cases of psychosis, personality disorder and substance abuse (n=249), 71 fulfilled criteria for schizophrenia, including all of the 37 cases in the register and an additional 34 (48% false-negatives), most frequently diagnosed in the register as schizophreniform or other psychosis. Despite the official use of DSM-III-R nomenclature, it appears that the clinical concept of schizophrenia in Finland, manifest within the register, remains very restrictive. The application of operational criteria is a necessary prerequisite for scientific research on schizophrenia.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Mähönen M (1993) Poistoilmoitusrekisteri sepelvaltimotaudin epidemiologisen tutkimuksen tietolähteenä. (The reliability of hospital discharge data as a tool for epidemiologic research on ischemic heart disease). National Research and Development Centre for Welfare and Health, vol 28. Helsinki (English summary)

    Google Scholar 

  2. Koskenvuo M, Kaprio J, Romo M, Langinvainio H (1981) Incidence and prognosis of ischaemic heart disease with respect to marital status and social class. J Epidemiol Community Health 35: 192–196

    Google Scholar 

  3. Poikolainen K (1983) Accuracy of hospital discharge data five alcohol-related diseases. Drug Alcohol Depend 12: 315–322

    Google Scholar 

  4. Keskimäki I, Aro S (1991) The accuracy of data on diagnoses, procedures and accidents in the Finnish Hospital Discharge Register. Int J Health Sci 2: 15–21

    Google Scholar 

  5. Aro S, Aro H, Salinto M, Keskimäki I (1995) Educational level and hospital use in mental disorders. Acta Psychiatr Scand 91: 305–321

    Google Scholar 

  6. WHO (1977) Manual of the international statistical classification of diseases, injuries and causes of death, 9th revision, vol 1. WHO, Geneva

    Google Scholar 

  7. Kuoppasalmi K, Lönnqvist J, Pylkkänen K, Huttunen M (1989) Classification of mental disorders in Finland. A comparison of the Finnish classification of mental disorders in 1987 with DSM-III-R. Psychiatr Fenn 20: 65–81

    Google Scholar 

  8. American Psychiatric Association (1987) DSM-III-R: diagnostic and statistical manual of mental disorders, 3rd edn, revised. American Psychiatric Association. Washington, DC

    Google Scholar 

  9. Rantakallio P (1988) The longitudinal study of the Northern Finland birth cohort of 1966. Pediatr Perinat Epidemiol 2: 59–88

    Google Scholar 

  10. Isohanni M, Oja H, Moilanen I, Koiranen M, Rantakallio P (1995) Smoking or quitting during pregnancy: associations with background and future social factors. Scand J Soc Med 23: 32–38

    Google Scholar 

  11. Rantakallio P, Myhrman A, Koiranen M (1995) Juvenile offenders, with special reference to sex differences. Soc Psychiatry Psychiatr Epidemiol 30: 113–120

    Google Scholar 

  12. McCuffin P, Farmer AE, Harvey I (1991) A polydiagnostic application of operational criteria in psychotic illness: development and reliability of the OPCRIT system. Arch Gen Psychiatry 48: 764–770

    Google Scholar 

  13. Tienari P, Wynne LC, Moring J, Wahlberg K-E, Sorri A, Naarala M, Lahti I (1993) Genetic vulnerability or family environment? Implications from the Finnish adoptive family study of schizophrenia. Psychiatr Fenn 24: 23–41

    Google Scholar 

  14. Jablensky A (1993) The epidemiology of schizophrenia. Curr Opin Psychiatry 6: 43–52

    Google Scholar 

  15. Faraone S, Chen WJ, Goldstein JM, Tsuang MT (1994) Gender differences in age at onset of schizophrenia. Br J Psychiatry 164: 625–629

    Google Scholar 

  16. Häfner H, Maurer K, Loffler W, Riechel-Rüssler A (1991) Schizophrenic und Lebensalter. Nervenarzt 62: 536–548

    Google Scholar 

  17. Lehtinen V, Joukamaa M (1987) Mental disorders in a sample representative of the whole Finnish adult population. In: Cooper B (ed) Psychiatric epidemiology, progress and prospects. Croom Helm, London, pp 43–54

    Google Scholar 

  18. Lehtinen V, Väisänen E (1981) Epidemiology of psychiatric disorders in Finland. A five-year follow-up. Soc Psychiatry 16: 171–180

    Google Scholar 

  19. Väisänen E (1975) Psychiatric disorders in Finland. Acta Psychiatr Scand 263 [Suppl]: 22–33

    Google Scholar 

  20. Keith SJ, Regier DA, Rae DS (1991) Schizophrenic disorders. In: Robins LN, Regier DA (eds) Psychiatric disorders in America. Free Press, New York, pp 33–52

    Google Scholar 

  21. Andreasen NC, Carpenter WT (1993) Diagnosis and classification of schizophrenia. Schizophr Bull 19: 199–214

    Google Scholar 

  22. Jones P, Rodgers B, Murray R, Marmot M (1994) Child developmental risk factors for adult schizophrenia in the British 1946 birth cohort. Lancet 344: 1398–1402

    Google Scholar 

  23. Cohen SI (1995) Overdiagnosis of schizophrenia: role of alcohol and drug misuse. Lancet 346: 1541–1542

    Google Scholar 

  24. World Health Organization (1973) The international pilot study of schizophrenia. WHO, Geneva

    Google Scholar 

  25. Robins LN, Ratcliff KS, Seyfried W (1982) Validity of the Diagnostic Interview Schedule, version II: DSM-III diagnoses. Psychol Med 12: 855–870

    Google Scholar 

  26. Erdman HP, Klein MH, Greist JH, Bass SM, Bires JK, Mactinger PE (1987) A comparison of the Diagnostic Interview Schedule and clinical diagnosis. Am J Psychiatry 144: 1477–1780

    Google Scholar 

  27. Fenning S, Craig TJ, Tanenberg-Karant M, Bromet EJ (1994) Comparison of facility and research diagnoses in first admission psychotic patients. Am J Psychiatry 151: 1423–1429

    Google Scholar 

  28. Pakaslahti A (1986) Principles and practices in diagnosine schizophrenia (dissertation). Publications of the Social Insurance Institution ML 57, Helsinki

  29. Kuusi K (1986) Skitsofreenisten psykoosien ennuste Helsingissä 1975–1983 (dissertation). (Prognosis of schizophrenic psychoses in Helsinki 1975–1983.) Monographs of Psychiatria Fennica 13, Helsinki

  30. Nieminen P, Isohanni M, Winblad I (1994) Length of hospitalization in an acute patients' therapeutic community ward. Acta Psychiatr Scand 90: 466–472

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Isohanni, M., Mäkikyrö, T., Moring, J. et al. A comparison of clinical and research DSM-III-R diagnoses of schizophrenia in a Finnish national birth cohort. Soc Psychiatry Psychiatr Epidemiol 32, 303–308 (1997). https://doi.org/10.1007/BF00789044

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00789044

Keywords

Navigation