Abstract
Chromatid interchange between somatic chromosomes, a phenomenon occasionally observed in normal lymphocytes in culture, occurs with a greatly increased frequency in Bloom's syndrome lymphocytes. Highly characteristic interchanges occur at apparently homologous sites on homologous chromosomes and affect certain regions preferentially.
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German, J., Crippa, L.P. & Bloom, D. Bloom's syndrome. III. Analysis of the chromosome aberration characteristic of this disorder. Chromosoma 48, 361–366 (1974). https://doi.org/10.1007/BF00290993
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DOI: https://doi.org/10.1007/BF00290993