Summary
Sixty patients with mild to moderate forms of eczematous otitis externa were treated with budesonide and placebo in a double-blind controlled study using parallel groups. Each treatment period was preceded by otomicroscopic examination and thorough cleaning of the ear canal. The symptoms and signs were assessed with a score system ranging from 0 (no symptoms/signs) to 3 (severe symptoms/signs). Budesonide treatment was associated with a reduction in severity of all symptoms recorded and a marked improvement in erythema, swelling and discharge. Mechanical cleaning of the ear canal and placebo was not a sufficient treatment for this group of patients.
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References
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Jacobsson, S., Karlsson, G., Rignér, P. et al. Clinical efficacy of budesonide in the treatment of eczematous external otitis. Eur Arch Otorhinolaryngol 248, 246–249 (1991). https://doi.org/10.1007/BF00173665
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DOI: https://doi.org/10.1007/BF00173665