Skip to main content

Advertisement

Log in

Suicidality in Autism Spectrum Disorder: a Commentary

  • Commentary
  • Published:
Advances in Neurodevelopmental Disorders Aims and scope Submit manuscript

Abstract

Recent studies report a higher prevalence of suicidality (ideation, attempts and deaths by suicide) among individuals with autism spectrum disorder (ASD) than in the general population. Unfortunately, there is little research addressing the conceptualization and management of suicidality in the ASD population. In this commentary, we explore potential modifications in the processes leading to suicidality in individuals with ASD and considerations relevant to clinical support and service development. Specifically, based on a multilevel framework, we highlight individual, contextual and systemic risk factors of suicidality in the ASD population noted in the literature. We discuss how patterns of ASD-related behaviours may modify specific pathways in theories of suicide as developed for the general population. We explore how ASD symptomology may contribute to maladaptive coping strategies and dynamics between those with ASD and their care providers. Considerations for prevention and proactive responses at various levels of practice and implications for support and service development are discussed as future directions in the field.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Alice, S. C., David, O. B., Sonia, T., Christine, E. C., Mary Beth, K., & Helen, T.-F. (2007). Sex differences in toddlers with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37(1), 86–97. doi:10.1007/s10803-006-0331-7.

    Article  Google Scholar 

  • Arnett, J. J. (2000). Emerging adulthood. A theory of development from the late teens through the twenties. American Psychologist, 55(5), 469–480.

    Article  PubMed  Google Scholar 

  • Balfe, M., & Tantam, D. (2010). A descriptive social and health profile of a community sample of adults and adolescents with Asperger syndrome. BMC Research Notes, 3(1). doi: 10.1186/1756-0500-3-300.

  • Baron-Cohen, S., Lombardo, M. V., Auyeung, B., Ashwin, E., Chakrabarti, B., & Knickmeyer, R. (2011). Why are autism spectrum conditions more prevalent in males? PLoS Biology, 9(6), e1001081. doi:10.1371/journal.pbio.1001081.

    Article  PubMed  PubMed Central  Google Scholar 

  • Bennett, M. (2015). The importance of interviewing adults on the autism spectrum about their depression and suicidal ideation experiences. Journal of Autism and Developmental Disorders, 46(4), 1492–1493. doi:10.1007/s10803-015-2674-4.

    Article  Google Scholar 

  • Bowers, E. P., Geldhof, J. G., Johnson, S. K., Lerner, J. V., & Lerner, R. M. (2014). Special issue introduction: thriving across the adolescent years: a view of the issues. Journal of Youth and Adolescence, 43(6), 859–868. doi:10.1007/s10964-014-0117-8.

    Article  PubMed  Google Scholar 

  • Brown-Lavoie, S. M., Viecili, M. A., & Weiss, J. A. (2014). Sexual knowledge and victimization in adults with autism spectrum disorders. Journal of Autism and Developmental DisordersJournal of Autism and Developmental Disorders, 44(9), 2185–2196. doi:10.1007/s10803-014-2093-y.

    Article  Google Scholar 

  • Cassidy, S., Bradley, P., Robinson, J., Allison, C., McHugh, M., & Baron-Cohen, S. (2014). Suicidal ideation and suicide plans or attempts in adults with Aspergerʼs syndrome attending a specialist diagnostic clinic: a clinical cohort study. The Lancet Psychiatry, 1(2). doi: 10.1016/s2215-0366(14)70248-2.

  • Cummins, R. A. (1996). The domains of life satisfaction: an attempt to order chaos. Social Indicators Research, 38(3), 303–328. doi:10.1007/bf00292050.

    Article  Google Scholar 

  • Cummins, R. A. (2005). Moving from the quality of life concept to a theory. Journal of Intellectual Disability Research, 49(10), 699–706. doi:10.1111/j.1365-2788.2005.00738.x.

    Article  PubMed  Google Scholar 

  • Dazzi, T., Gribble, R., Wessely, S., & Fear, N. T. (2014). Does asking about suicide and related behaviours induce suicidal ideation? What is the evidence? Psychological Medicine, 44(16), 3361–3363. doi:10.1017/s0033291714001299.

    Article  PubMed  Google Scholar 

  • Fuller-Thomson, E., Baird, S. L., Dhrodia, R., & Brennenstuhl, S. (2016). The association between adverse childhood experiences (ACEs) and suicide attempts in a population-based study. Child: Care, Health and Development, 42(5), 725–734. doi:10.1111/cch.12351.

    Google Scholar 

  • Fung, S., Lunsky, Y., & Weiss, J. A. (2015). Depression in youth with autism spectrum disorder: The role of ASD vulnerabilities and family–environmental stressors. Journal of Mental Health Research in Intellectual Disabilities, 8(3–4), 120–139. doi:10.1080/19315864.2015.1017892.

    Article  Google Scholar 

  • Ghaziuddin, M., Alessi, N., & Greden, J. F. (1995). Life events and depression in children with pervasive developmental disorders. Journal of Autism and Developmental Disorders, 25(5), 495–502. doi:10.1007/bf02178296.

    Article  PubMed  Google Scholar 

  • Gotham, K., Unruh, K., & Lord, C. (2015). Depression and its measurement in verbal adolescents and adults with autism spectrum disorder. Autism: the international journal of research and practice, 19(4), 491–504. doi:10.1177/1362361314536625.

    Article  Google Scholar 

  • Gunn III, J. F., & Lester, D. (2014). Theories of suicide: past, present and future. Springfield: Charles C Thomas ISBN (Print) 978-0-398-08090-7.

    Google Scholar 

  • Hawton, K. (2000). Sex and suicide. Gender differences in suicidal behaviour. The British Journal of Psychiatry, 177, 484–485.

    Article  PubMed  Google Scholar 

  • Hirvikoski, T., Mittendorfer-Rutz, E., Boman, M., Larsson, H., Lichtenstein, P., & Bolte, S. (2016). Premature mortality in autism spectrum disorder. The British Journal of Psychiatry, 208(3), 232–238. doi:10.1192/bjp.bp.114.160192.

    Article  PubMed  Google Scholar 

  • Hom, M. A., Stanley, I. H., & Joiner, T. E. (2015). Evaluating factors and interventions that influence help-seeking and mental health service utilization among suicidal individuals: a review of the literature. Clinical Psychology Review, 40. doi:10.1016/j.cpr.2015.05.006.

  • Insel, T., Cuthbert, B., Garvey, M., Heinssen, R., Pine, D. S., Quinn, K., & Wang, P. (2010). Research domain criteria (RDoC): toward a new classification framework for research on mental disorders. The American Journal of Psychiatry, 167(7), 748–751. doi:10.1176/appi.ajp.2010.09091379.

    Article  PubMed  Google Scholar 

  • Joiner Jr., T. E., Brown, J. S., & Wingate, L. R. (2005). The psychology and neurobiology of suicidal behavior. Annual Review of Psychology, 56, 287–314. doi:10.1146/annurev.psych.56.091103.070320.

    Article  PubMed  Google Scholar 

  • Kato, K., Mikami, K., Akama, F., Yamada, K., Maehara, M., Kimoto, K., & Matsumoto, H. (2013). Clinical features of suicide attempts in adults with autism spectrum disorders. General Hospital Psychiatry, 35(1). doi:10.1016/j.genhosppsych.2012.09.006.

  • Lai, M. C., Lombardo, M. V., Suckling, J., Ruigrok, A. N., Chakrabarti, B., Ecker, C., & Baron-Cohen, S. (2013). Biological sex affects the neurobiology of autism. Brain, 136(Pt 9), 2799–2815. doi:10.1093/brain/awt216.

    Article  PubMed  PubMed Central  Google Scholar 

  • Lebowitz, E. R. (2016). “Failure to launch”: shaping intervention for highly dependent adult children. Journal of the American Academy of Child & Adolescent Psychiatry, 55(2). doi: 10.1016/j.jaac.2015.10.014.

  • Lerner, R. M. (2006). Resilience as an attribute of the developmental system: comments on the papers of Professors Masten & Wachs. Annals of the New York Academy of Sciences, 1094, 40–51. doi:10.1196/annals.1376.005.

    Article  PubMed  Google Scholar 

  • Mandell, D. S., Walrath, C. M., Manteuffel, B., Sgro, G., & Pinto-Martin, J. A. (2005). The prevalence and correlates of abuse among children with autism served in comprehensive community-based mental health settings. Child Abuse & Neglect, 29(12), 1359–1372. doi:10.1016/j.chiabu.2005.06.006.

    Article  Google Scholar 

  • Mandy, W., Chilvers, R., Chowdhury, U., Salter, G., Seigal, A., & Skuse, D. (2011). Sex differences in autism spectrum disorder: evidence from a large sample of children and adolescents. Journal of Autism and Developmental Disorders, 42(7), 1304–1313. doi:10.1007/s10803-011-1356-0.

    Article  Google Scholar 

  • Matson, J. L., & Williams, L. W. (2014). Depression and mood disorders among persons with autism spectrum disorders. Research in Developmental Disabilities, 35(9), 2003–2007. doi:10.1016/j.ridd.2014.04.020.

    Article  PubMed  Google Scholar 

  • Mayes, S. D., Gorman, A. A., & Hillwig-Garcia, J. (2013). Suicide ideation and attempts in children with autism. Research in Autism Spectrum Disorders, 7(1). doi: 10.1016/j.rasd.2012.07.009.

  • McMorris, C. A., & Perry, A. (2015). Examining the criterion-related validity of the pervasive developmental disorder behavior inventory. Autism: the international journal of research and practice, 19(3). doi: 10.1177/1362361313518123.

  • O’Connor, R. C. (2011). The integrated motivational-volitional model of suicidal behavior. Crisis, 32, 295–298. doi:10.1027/0227-5910/a000120.

    Article  PubMed  Google Scholar 

  • O’Connor, R. C., & Nock, M. K. (2014). The psychology of suicidal behaviour. Lancet Psychiatry, 1(1), 73–85. doi:10.1016/S2215-0366(14)70222-6.

    Article  PubMed  Google Scholar 

  • Paquette-Smith, M., Weiss, J., & Lunsky, Y. (2014). History of suicide attempts in adults with Asperger syndrome. Crisis, 35(4), 273–277. doi:10.1027/0227-5910/a000263.

    Article  PubMed  Google Scholar 

  • Power, E., Clarke, M., Kelleher, I., Coughlan, H., Lynch, F., Connor, D., & Cannon, M. (2015). The association between economic inactivity and mental health among young people: a longitudinal study of young adults who are not in employment, education or training. Irish Journal of Psychological Medicine, 32(01), 155–160. doi:10.1017/ipm.2014.85.

    Article  Google Scholar 

  • Richa, S., Fahed, M., Khoury, E., & Mishara, B. (2014). Suicide in autism spectrum disorders. Archives of Suicide Research, 18(4), 327–339. doi:10.1080/13811118.2013.824834.

    Article  PubMed  Google Scholar 

  • Rodgers, J., Wigham, S., McConachie, H., Freeston, M., Honey, E., & Parr, J. R. (2016). Development of the anxiety scale for children with autism spectrum disorder (ASC-ASD). Autism Research : official journal of the International Society for Autism Research, 9(11), 1205–1215. doi:10.1002/aur.1603.

    Article  Google Scholar 

  • Segers, M., & Rawana, J. (2014). What do we know about suicidality in autism spectrum disorders? A systematic review. Autism Research : official journal of the International Society for Autism Research, 7(4), 507–521. doi:10.1002/aur.1375.

    Article  Google Scholar 

  • Sentenac, M., Arnaud, C., Gavin, A., & Molcho, M. (2011). Peer victimization among school-aged children with chronic conditions. Epidemiologic Reviews, 34(1), 120–128. doi:10.1093/epirev/mxr024.

    Article  PubMed  Google Scholar 

  • Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child & Adolescent Psychiatry, 47(8), 921–929. doi:10.1097/CHI.0b013e318179964f.

    Article  Google Scholar 

  • Stellrecht, N. E., Gordon, K. H., Van Orden, K., Witte, T. K., Wingate, L. R., Cukrowicz, K. C., & Joiner Jr., T. E. (2006). Clinical applications of the interpersonal-psychological theory of attempted and completed suicide. Journal of Clinical Psychology, 62(2), 211–222. doi:10.1002/jclp.20224.

    Article  PubMed  Google Scholar 

  • Storch, E. A., Sulkowski, M. L., Nadeau, J., & Lewin, A. B. (2013). The phenomenology and clinical correlates of suicidal thoughts and behaviors in youth with autism spectrum disorders. Journal of Autism and Developmental Disorders, 43(10). doi: 10.1007/s10803-013-1795-x.

  • Taylor, J. L., & Gotham, K. O. (2016). Cumulative life events, traumatic experiences, and psychiatric symptomatology in transition-aged youth with autism spectrum disorder. Journal of Neurodevelopmental Disorders, 8, 28. doi:10.1186/s11689-016-9160-y.

    Article  PubMed  PubMed Central  Google Scholar 

  • Taylor, J. L., & Seltzer, M. M. (2011). Employment and post-secondary educational activities for young adults with autism spectrum disorders during the transition to adulthood. Journal of Autism and Developmental Disorders, 41(5), 566–574.

    Article  PubMed  PubMed Central  Google Scholar 

  • Van Orden, K. A., Witte, T. K., Cukrowicz, K. C., Braithwaite, S. R., Selby, E. A., & Joiner Jr., T. E. (2010). The interpersonal theory of suicide. Psychological Review, 117(2), 575–600. doi:10.1037/a0018697.

    Article  PubMed  PubMed Central  Google Scholar 

  • Wood, J. J., & Gadow, K. D. (2010). Exploring the nature and function of anxiety in youth with autism spectrum disorders. Clinical Psychology: Science and Practice, 17(4), 281–292. doi:10.1111/j.1468-2850.2010.01220.x.

    Google Scholar 

  • Wyman, P. A., Brown, C. H., Inman, J., Cross, W., Schmeelk-Cone, K., Guo, J., & Pena, J. B. (2008). Randomized trial of a gatekeeper program for suicide prevention: 1-year impact on secondary school staff. Journal of Consulting and Clinical Psychology, 76(1), 104–115. doi:10.1037/0022-006X.76.1.104.

    Article  PubMed  PubMed Central  Google Scholar 

  • Yur'yev, A., Varnik, A., Varnik, P., Sisask, M., & Leppik, L. (2010). Employment status influences suicide mortality in Europe. International Journal of Social Psychiatry, 58(1), 62–68. doi:10.1177/0020764010387059.

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

We would like to thank Dr. Jonathan Weiss, Dr. Yona Lunsky and Jeri Kendle for sharing their clinical and community work experience, and thus contributing to the development of this paper.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jonathan K.Y. Lai.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lai, J.K., Rhee, E. & Nicholas, D. Suicidality in Autism Spectrum Disorder: a Commentary. Adv Neurodev Disord 1, 190–195 (2017). https://doi.org/10.1007/s41252-017-0018-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s41252-017-0018-4

Keywords

Navigation