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Validation of the Chinese version of EORTC QLQ-BM22 in patients with bone metastases

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Abstract

Purpose

Our aim is to test the validity, reliability, and acceptability of the Chinese version of European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Bone Metastases 22 (EORTC QLQ-BM22) module to assess health-related quality of life (HRQOL) in patients with bone metastases in China.

Methods

Patients with histological confirmation of malignancy and bone metastases from Tianjin Cancer Institution and Hospital from June 2013 to April 2014 were enrolled in this study. All patients self-administered the EORTC QLQ-BM22 and the EORTC QLQ-C30. The Karnofsky Performance Scale (KPS) was performed to evaluate scores. The reliability and validity tests of the questionnaires were based on Cronbach’s α coefficients, Pearson correlation test, and Wilcoxon rank sum nonparametric test.

Results

Internal consistency reliabilities of all the four scales were acceptable. Scales measuring similar HRQOL aspects were found to correlate with one another between EORTC QLQ-BM22 and EORTC QLQ-C30, but differences still existed. Significant differences were demonstrated in the scores of all four subscales of the QLQ-BM22 between the two KPS subgroups (KPS ≤ 80; KPS > 80). Meanwhile, the compliance for item completion of the QLQ-BM22 was satisfactory.

Conclusions

The Chinese version of EORTC QLQ-BM22 is a reliable and valid instrument, which is appropriate for measuring the HRQOL of patients with bone metastases in China.

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References

  1. Chow E, Nguyen J, Zhang L, Tseng LM, Hou MF, Fairchild A et al (2012) International field testing of the reliability and validity of the EORTC QLQ-BM22 module to assess health-related quality of life in patients with bone metastases. Cancer 118(5):1457–1465. doi:10.1002/cncr.26410

    Article  PubMed  Google Scholar 

  2. Wan C, Meng Q, Yang Z, Tu X, Feng C, Tang X, Zhang C (2008) Validation of the simplified Chinese version of EORTC QLQ-C30 from the measurements of five types of inpatients with cancer. Ann Oncol 19:2053–2060. doi:10.1093/annonc/mdn417

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  3. Chow E, Hird A, Velikova G, Johnson C, Dewolf L, Bezjak A et al (2009) The European Organization for research and treatment of cancer quality of life questionnaire for patients with bone metastases: the EORTC QLQ-BM22. Eur J Cancer 45(7):1146–1152. doi:10.1016/j.ejca.2008.11.013

    Article  PubMed  Google Scholar 

  4. Zeng L, Chow E, Bedard G, Zhang L, Fairchild A, Vassiliou V et al (2012) Quality of life after palliative radiation therapy for patients with painful bone metastases: results of an international study validating the EORTC QLQ-BM22. Int J Radiat Oncol Biol Phys 84(3):e337–e342. doi:10.1016/j.ijrobp.2012.05.028

    Article  PubMed  Google Scholar 

  5. Chow E, Bottomley A (2009) Understanding the EORTC QLQ-BM22, the module for patients with bone metastases. Expert Rev Pharmacoecon Outcomes Res 9(5):461–465. doi:10.1586/erp.09.50

    Article  PubMed  Google Scholar 

  6. Fayers PM, Aaronson NK, Bjordal K, Groenvold M, Curran D, Bottomley A et al (2011) The EORTC QLQC30 Scoring Manual. 3rd ed. Brussels, Belgium. European Organization for research and treatment of cancer. Support Care Cancer 19(11):1753–1760

    Article  Google Scholar 

  7. Püsküllüoğlu M, Tomaszewski KA, Bottomley A, Holden L, Tomaszewska TM, Głowacki R et al (2014) Validation of the Polish version of the EORTC QLQ-BM22 module for the assessment of health-related quality of life in patients with bone metastases. Qual Life Res 23(2):527–532. doi:10.1007/s11136-013-0486-6

    Article  PubMed  Google Scholar 

  8. Broom R, Du H, Clemons M, Eton D, Dranitsaris G, Simmons C, Ooi W, Cella D (2008) Switching breast cancer patients with progressive bone metastases to third-generation bisphosphonates: measuring impact using the functional assessment of cancer therapy-bone pain. J Pain Symptom Manage 38(2):244–257. doi:10.1016/j.jpainsymman.2008.08.005

    Article  Google Scholar 

  9. Popovic M, Nguyen J, Chen E, Di Giovanni J, Liang Z, Chow E (2012) Comparison of the EORTC QLQ-BM22 and the FACT-BP for assessment of quality of life in cancer patients with bone metastases. Expert Rev Pharmacoecon Outcomes Res 12(2):213–219. doi:10.1586/erp.11.99

    Article  PubMed  Google Scholar 

  10. Yekaninejad MS, Ahmadzadeh A, Mosavi SH, Saffari M, Pakpour AH, Tolooei F, Chow E, Bottomley A (2014) The reliability and validity of the Iranian version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire for patients with Bone Metastases: the EORTC QLQ-BM22.Expert. Rev Pharmacoecon Outcomes Res 14(1):147–156. doi:10.1586/14737167.2014.864559

    Article  Google Scholar 

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Conflict of interest

The authors declare that they have no conflict of interest.

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Author notes

    Authors and Affiliations

    1. Department of Thoracic Surgery, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin Lung Cancer Center, Tianjin, 300060, People’s Republic of China

      Lei Zhang, Yan-Jun Su & Chang-Li Wang

    2. Department of Bone and Softissue Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, People’s Republic of China

      Zhi-Chao Liao

    3. Tianjin Medical University, Tianjin, People’s Republic of China

      Jia-Yue Chen, Jing Zhang, Yun-Shou Lin, Hui Guo & Wei-Lin Sun

    4. Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, People’s Republic of China

      Zhi-Qin Luo

    5. Xiangya School of Medicine, Central South University, Changsha, People’s Republic of China

      Shu-Min Xie, Yu-Hua Rui & Mo-Han Li

    6. Erasmus University Rotterdam, Rotterdam, Netherlands

      Begüm Pekbay

    7. Indiana University School of Medicine, Indianapolis, IN, USA

      Adam R Miller

    8. Department of Radiation Oncology, Tumor Hospital Xiangya School of Medicine of Central South University, Changsha, People’s Republic of China

      Le Luo

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    1. Lei Zhang
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    2. Yan-Jun Su
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    16. Chang-Li Wang
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    Corresponding author

    Correspondence to Chang-Li Wang.

    Additional information

    Lei Zhang, Yan-Jun Su, Jia-Yue Chen, Zhi-Chao Liao, Shu-Min Xie, Jing Zhang, Yun-Shou Lin, Wei-Lin Sun and Begüm Pekbay contributed equally to this work.

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    Zhang, L., Su, YJ., Chen, JY. et al. Validation of the Chinese version of EORTC QLQ-BM22 in patients with bone metastases. Support Care Cancer 24, 1019–1024 (2016). https://doi.org/10.1007/s00520-015-2870-y

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    • DOI: https://doi.org/10.1007/s00520-015-2870-y

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