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Predictors of return to work for people on sick leave with common mental disorders: a systematic review and meta-analysis

  • Review Article
  • Published:
International Archives of Occupational and Environmental Health Aims and scope Submit manuscript

Abstract

Purpose

To support the return to work following common mental disorders knowing which factors influence the return to work is important. We aimed to identify factors predicting return to work for people on sick leave with disorders like stress, anxiety, and depression.

Methods

A systematic review and meta-analyses were conducted regarding return to work at any time point, < 3 months, 3–12 months, and > 12 months of sick leave, respectively, and diagnostic subgroups.

Results

The meta-analyses included 29 studies. Predictors decreasing return to work probability at any time point were higher age, being male, neuroticism and openness, previous sickness absence, and higher symptom scores. Predictors increasing return to work probability were positive return to work expectations, high return to work- and general self-efficacy, conscientiousness, and high workability index. Return to work within < 3 months of sick leave was associated with positive return to work expectations. Return to work after > 12 months was increased by higher education. Higher age was associated with decreased return to work probability after > 12 months. No significant predictors were found in diagnostic subgroups.

Conclusion

Results are overall consistent with earlier reviews. Future studies should focus on specific time points, diagnostic subgroups, and work-related factors.

Prospero registration ID

CRD42018073396.

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Data availability

Data are available from the corresponding author upon request.

References

  • Arends I, Almansa J, Stansfeld SA, Amick BC, van der Klink JJL, Bültmann U (2019) One-year trajectories of mental health and work outcomes post return to work in patients with common mental disorders. J Affect Disord 257:263–270

    Article  CAS  Google Scholar 

  • Audhoe SS, Hoving JL, Nieuwenhuijsen K, Friperson R, De Jong PR, Sluiter JK et al (2012) Prognostic factors for the work participation of sick-listed unemployed and temporary agency workers with psychological problems. J Occup Rehabil 22(4):437–446

    Article  Google Scholar 

  • Brouwers EPM, Tiemens BG, Terluin B, Verhaak PFM (2006) Effectiveness of an intervention to reduce sickness absence in patients with emotional distress or minor mental disorders: a randomized controlled effectiveness trial. Gen Hosp Psychiatry 28(3):223–229

    Article  Google Scholar 

  • Brouwers EPM, Terluin B, Tiemens BG, Verhaak PFM (2009) Predicting return to work in employees sick-listed due to minor mental disorders. J Occup Rehabil 19(4):323–332

    Article  Google Scholar 

  • Brouwer S, Reneman MF, Bültmann U, Van Der Klink JJL, Groothoff JW (2010) A prospective study of return to work across health conditions: perceived work attitude, self-efficacy and perceived social support. J Occup Rehabil 20(1):104–112

    Article  Google Scholar 

  • Burke-Miller JK, Cook JA, Grey DD, Razzano LA, Blyler CR, Leff HS et al (2006) Demographic characteristics and employment among people with severe mental illness in a multisite study. Community Ment Health J 42(2):143–159

    Article  Google Scholar 

  • Cornelius LR, Van Der Klink JJL, Groothoff JW, Brouwer S (2011) Prognostic factors of long term disability due to mental disorders: a systematic review. J Occup Rehabil 21(2):259–274

    Article  CAS  Google Scholar 

  • Covidence - Accelerate your systematic review [Internet]. [cited 2018 May 2]. Available from: https://www.covidence.org/

  • de Vente W, Kamphuis JH, Blonk RWB, Emmelkamp PMG (2015) Recovery of work-related stress: complaint reduction and work-resumption are relatively independent processes. J Occup Rehabil 25(3):658–668

    Article  Google Scholar 

  • Dewa CS, Hoch JS, Lin E, Paterson M, Goering P (2003) Pattern of antidepressant use and duration of depression-related absence from work. Br J Psychiatry 183:507–513

    Article  Google Scholar 

  • Ekberg K, Wåhlin C, Persson J, Bernfort L, Öberg B (2015) Early and late return to work after sick leave: predictors in a cohort of sick-listed individuals with common mental disorders. J Occup Rehabil 25(3):627–637

    Article  Google Scholar 

  • Eklund M, Wastberg BA, Erlandsson LKK (2013) Work outcomes and their predictors in the Redesigning Daily Occupations (ReDO) rehabilitation programme for women with stress-related disorders. Aust Occup Ther J 60:85–92

    Article  Google Scholar 

  • Ervasti J, Joensuu M, Pentti J, Oksanen T, Ahola K, Vahtera J et al (2017) Prognostic factors for return to work after depression-related work disability: a systematic review and meta-analysis. J Psychiatr Res 95:28–36

    Article  Google Scholar 

  • Goldberg D (1994) A bio-social model for common mental disorders. Acta Psychiatr Scand 90:66–70

    Article  Google Scholar 

  • Hees HL, Koeter MWJ, Schene AH (2012) Predictors of long-term return to work and symptom remission in sick-listed patients with major depression. J Clin Psychiatry 73:1048–1055

    Article  Google Scholar 

  • Hellström L, Madsen T, Nordentoft M, Bech P, Eplov LF (2017) Trajectories of return to work among people on sick leave with mood or anxiety disorders: secondary analysis from a randomized controlled trial. J Occup Rehabil 28(4):666–677

    Article  Google Scholar 

  • Huijs JJJM, Koppes LLJ, Taris TW, Blonk RWB (2017) Work characteristics and return to work in long-term sick-listed employees with depressive symptoms. J Occup Rehabil 27(4):612–622

    Article  Google Scholar 

  • Kausto J, Pentti J, Oksanen T, Virta LJ, Virtanen M, Kivimaki M et al (2017) Length of sickness absence and sustained return-to-work in mental disorders and musculoskeletal diseases: a cohort study of public sector employees. Scand J Work Environ Health 43(4):358–366

    Article  Google Scholar 

  • Koopmans PC, Bültmann U, Roelen CAM, Hoedeman R, Van Der Klink JJL, Groothoff JW (2011) Recurrence of sickness absence due to common mental disorders. Int Arch Occup Environ Health 84(2):193–201

    Article  Google Scholar 

  • Kronström K, Karlsson H, Nabi H, Oksanen T, Salo P, Sjösten N et al (2011) Optimism and pessimism as predictors of work disability with a diagnosis of depression: a prospective cohort study of onset and recovery. J Affect Disord 130(1–2):294–299. https://doi.org/10.1016/j.jad.2010.10.003

    Article  Google Scholar 

  • Lagerveld SE, Bültmann U, Franche RL, Van Dijk FJH, Vlasveld MC, Van Der Feltz-Cornelis CM et al (2010) Factors associated with work participation and work functioning in depressed workers: a systematic review. J Occup Rehabil 20(3):275–292

    Article  CAS  Google Scholar 

  • Lagerveld SE, Blonk RWB, Brenninkmeijer V, Wijngaards-de Meij L, Schaufeli WB et al (2012) Work-focused treatment of common mental disorders and return to work: a comparative outcome study. J Occup Health Psychol 17(2):220–234

    Article  Google Scholar 

  • Lagerveld SE, Brenninkmeijer V, Blonk RWB, Twisk J, Schaufeli WB (2017) Predictive value of work-related self-efficacy change on RTW for employees with common mental disorders. Occup Environ Med 74(5):381–383

    Article  Google Scholar 

  • Lammerts L, Schaafsma FG, Eikelenboom M, Vermeulen SJ, van Mechelen W, Anema JR et al (2016) Longitudinal associations between biopsychosocial factors and sustainable return to work of sick-listed workers with a depressive or anxiety disorder. J Occup Rehabil 26(1):70–79

    Article  Google Scholar 

  • Lidwall U (2015) Sick leave diagnoses and return to work: A Swedish register study. Disabil Rehabil 37(5):396–410

    Article  Google Scholar 

  • Mattila-Holappa P, Ervasti J, Joensuu M, Ahola K, Pentti J, Oksanen T et al (2017) Do predictors of return to work and recurrence of work disability due to mental disorders vary by age? A cohort study. Scand J Public Health. 45(2):178–184. https://doi.org/10.1177/1403494816686467

    Article  Google Scholar 

  • Nandi A, Beard JR, Galea S (2009) Epidemiologic heterogeneity of common mood and anxiety disorders over the lifecourse in the general population: a systematic review. BMC Psychiatry 9:31

    Article  Google Scholar 

  • Netterstrøm B, Friebel L, Ladegaard Y (2013) Effects of a multidisciplinary stress treatment programme on patient return to work rate and symptom reduction: results from a randomised, wait-list controlled trial. Psychother Psychosom 82(3):177–186

    Article  Google Scholar 

  • Netterstrøm B, Eller NH, Borritz M (2015) Prognostic factors of returning to work after sick leave due to work-related common mental disorders: a one- and three-year follow-up study. Biomed Res Int 2015:1–7

    Article  CAS  Google Scholar 

  • Nielsen MBD, Madsen IEH, Bültmann U, Christensen U, Diderichsen F, Rugulies R et al (2011) Predictors of return to work in employees sick-listed with mental health problems: findings from a longitudinal study. Eur J Public Health 21(6):806–811

    Article  Google Scholar 

  • Nielsen MBD, Bültmann U, Madsen IEH, Martin M, Christensen U, Diderichsen F et al (2012) Health, work, and personal-related predictors of time to return to work among employees with mental health problems. Disabil Rehabil 34(15):1311–1316

    Article  Google Scholar 

  • Nieuwenhuijsen K, Verbeek JHAM, de Boer AGEM, Blonk RWB, van Dijk FJH (2004) Supervisory behaviour as a predictor of return to work in employees absent from work due to mental health problems. Occup Environ Med 61(10):817–823

    Article  CAS  Google Scholar 

  • Nieuwenhuijsen K, Verbeek JHAM, de Boer AGEM, Blonk RWB, van Dijk FJH (2006) Predicting the duration of sickness absence for patients with common mental disorders in occupational health care. Scand J Work Environ Health 32(1):67–74. https://doi.org/10.5271/sjweh.978

    Article  Google Scholar 

  • Nigatu YT, Liu Y, Uppal M, McKinney S, Rao S, Gillis K et al (2016) Interventions for enhancing return to work in individuals with a common mental illness: systematic review and meta-analysis of randomized controlled trials. Psychol Med 46(16):3263–3274

    Article  CAS  Google Scholar 

  • Norder G, Roelen CAM, van der Klink JJL, Bültmann U, Sluiter JK, Nieuwenhuijsen K (2017) External validation and update of a prediction rule for the duration of sickness absence due to common mental disorders. J Occup Rehabil 27(2):202–209

    Article  Google Scholar 

  • Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, The PRISMA et al (2020) statement: an updated guideline for reporting systematic reviews. BMJ. https://doi.org/10.1136/bmj.n71

    Article  Google Scholar 

  • Post M, Krol B, Groothoff J (2006) Self-rated health as a predictor of return to work among employees on long-term sickness absence. Disabil Rehabil 28(5):289–297

    Article  Google Scholar 

  • Poulsen R, Fisker J, Hoff A, Hjorthøj C, Eplov LF (2017a) Integrated mental health care and vocational rehabilitation to improve return to work rates for people on sick leave because of exhaustion disorder, adjustment disorder, and distress (the Danish IBBIS trial): Study protocol for a randomized controlled trial. Trials 18(1):579

    Article  Google Scholar 

  • Poulsen R, Hoff A, Fisker J, Hjorthøj C, Eplov LF (2017b) Integrated mental health care and vocational rehabilitation to improve return to work rates for people on sick leave because of depression and anxiety (the Danish IBBIS trial): Study protocol for a randomized controlled trial. Trials. https://doi.org/10.1186/s13063-017-2272-1

    Article  Google Scholar 

  • Poulsen R, Hoff A, Fisker J, Blom ES, Hjorthøj C, Eplov LF (2018) Integrated mental health care and vocational rehabilitation to improve return to work rates for people on sick leave because of common mental disorders (IBBIS): Study Protocol. Copenhagen

  • Roelen CAM, Norder G, Koopmans PC, Van Rhenen W, Van Der Klink JJL, Bültmann U (2012) Employees sick-listed with mental disorders: Who returns to work and when? J Occup Rehabil 22(3):409–417

    Article  CAS  Google Scholar 

  • Rotger GP (2021) Evaluering af Laer at tackle job og sygdom Et randomiseret kontrolleret studie af beskaeftigelseseffekten. [cited 2021 Sep 20]; Available from: www.vive.dk

  • Shiels C, Gabbay MB, Ford FM (2004) Patient factors associated with duration of certified sickness absence and transition to long-term incapacity. Br J Gen Pract 54(499):86–91

    Google Scholar 

  • Steel Z, Marnane C, Iranpour C, Chey T, Jackson JW, Patel V et al (2014) The global prevalence of common mental disorders: a systematic review and meta-analysis 1980–2013. Int J Epidemiol 43(2):476–493

    Article  Google Scholar 

  • van Beurden KM, van der Klink JJL, Brouwers EPM, Joosen MCW, Mathijssen JJP, Terluin B et al (2015) Effect of an intervention to enhance guideline adherence of occupational physicians on return-to-work self-efficacy in workers sick-listed with common mental disorders. BMC Public Health 15:796

    Article  Google Scholar 

  • Van Oostrom SH, Van Mechelen W, Terluin B, De Vet HCW, Knol DL, Anema JR (2010) A workplace intervention for sick-listed employees with distress: Results of a randomised controlled trial. Occup Environ Med 67(9):596–602

    Article  Google Scholar 

  • Victor M, Lau B, Ruud T (2017) Predictors of return to work among patients in treatment for common mental disorders: a pre-post study. BMC Public Health. https://doi.org/10.1186/s12889-017-4581-4

    Article  Google Scholar 

  • Victor M, Lau B, Ruud T (2018) Predictors of return to work 6 months after the end of treatment in patients with common mental disorders: a cohort study. J Occup Rehabil 28(3):548–558

    Article  Google Scholar 

  • Virtanen M, Kawachi I, Oksanen T, Salo P, Tuisku K, Pulkki-Råback L et al (2011) Socio-economic differences in long-term psychiatric work disability: prospective cohort study of onset, recovery and recurrence. Occup Environ Med 68(11):791–798

    Article  Google Scholar 

  • Volker D, Zijlstra-Vlasveld MC, Brouwers EPM, Van Lomwel AGC, Van Der Feltz-Cornelis CM (2014) Return-to-work self-efficacy and actual return to work among long-term sick-listed employees. J Occup Rehabil 25(2):423–431

    Article  Google Scholar 

  • Wåhlin C, Ekberg K, Persson J, Bernfort L, Oberg B, Wåhlin C et al (2012) Association between clinical and work-related interventions and return-to-work for patients with musculoskeletal or mental disorders. J Rehabil Med 44(4):355–362. https://doi.org/10.2340/16501977-0951

    Article  Google Scholar 

  • Wells G, Shea B, O’Connell D, Peterson J, Welch V, Losos M et al (2012). The Newcastle-Ottawa Scale (NOS) for assessing the quality if nonrandomized studies in meta-analyses. (Available from URL http//www.ohri.ca/programs/clinical_epidemiology/oxford.asp)

  • Young AE, Russell J (1995) Demographic, psychometric, and case progression information as predictors of return-to-work in teachers undergoing occupational rehabilitation. J Occup Rehabil 5(4):219–234

    Article  CAS  Google Scholar 

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Funding

This study is a part of the Danish IBBIS project which was funded by The Danish Agency for Labour Market and Recruitment (STAR).

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Contributions

All authors have participated in the planning of the review and discussion of the findings, and have critically reviewed and commented on the manuscript, and approved the final manuscript. JF, SSM, and LH have reviewed the literature and conducted the quality assessment of included studies. JF and CH have conducted the analyses. JF drafted the manuscript.

Corresponding author

Correspondence to Lone Hellström.

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The funding agency has not influenced neither the development, design, nor interpretation of this study. The authors report no conflict of interest.

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Fisker, J., Hjorthøj, C., Hellström, L. et al. Predictors of return to work for people on sick leave with common mental disorders: a systematic review and meta-analysis. Int Arch Occup Environ Health 95, 1–13 (2022). https://doi.org/10.1007/s00420-021-01827-3

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  • DOI: https://doi.org/10.1007/s00420-021-01827-3

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