Regular ArticleRegional Changes in Glucose Metabolism during Brain Development from the Age of 6 Years
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2014, Epilepsy ResearchCitation Excerpt :When compared with the adult control group, the two pediatric epileptic populations studied here showed common decrease in metabolism in various subcortical (caudate nuclei, accumbens, putamen and thalami), cortical and cerebellar areas. These cortical and subcortical hypometabolism are in close anatomical correspondence with those reported in a previous study that investigated the age-related changes in relative glucose metabolism from childhood to adulthood using a group of children with idiopathic rolandic epilepsy and a group of healthy adults (Van Bogaert et al., 1998). These regional metabolic differences between pediatric epileptic and adult populations might either be related to an effect of epilepsy or epileptic activity per se on regional brain glucose metabolism, or to age-related maturational processes.