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2019 | OriginalPaper | Hoofdstuk

12. Lichaamsmetabolisme

Auteur : Prof. dr. F.C. Schuit

Gepubliceerd in: Leerboek metabolisme en voeding

Uitgeverij: Bohn Stafleu van Loghum

Samenvatting

In H. 12 integreren we eerder aangebrachte elementen tot een globaal beeld van het lichaamsmetabolisme. We bekijken eerst de metabole verschillen tussen organen en twee belangrijke parameters: het handhaven van een normale bloedglucoseconcentratie (glucosehomeostase) en het bewaken van een normale voorraad van triglyceriden (vetreserve). Aandacht verdienen de sterke invloed van de voedingstoestand (gevoed, tussen maaltijden, vasten) en hoe insuline, glucagon, adrenaline en cortisol de flux in metabole wegen veranderen. Ook besteden we aandacht aan metabole veranderingen in skeletspieren om kortstondige of langdurige arbeid te ondersteunen. Vervolgens bekijken we diabetes (suikerziekte) als ontsporing van de glucosehomeostase en de rol van pancreatische bèta-cellen die ofwel vernietigd worden door het immuunsysteem (type-1-diabetes) ofwel slecht functioneren (type-2-diabetes). We eindigen met obesitas, een steeds groter wordend probleem voor de mensheid. Net als diabetes is obesitas een vorm van complexe ziekte. Vele risicogenen die elk kleine bijdragen leveren, interageren met een obesogene leefomgeving waarin voeding, beweging en bewuste keuze voor een gezonde levensstijl een rol spelen.

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Titel: Lichaamsmetabolisme
Auteur: Prof. dr. F.C. Schuit
Uitgeverij: Bohn Stafleu van Loghum
Boek: Leerboek metabolisme en voeding
Print ISBN: 978-90-368-2357-9

Elektronisch ISBN: 978-90-368-2358-6

Copyright: 2019
DOI: https://doi.org/10.1007/978-90-368-2358-6_12

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

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