Level of Functioning in Autism Spectrum Disorders: Phenotypic Congruence Among Affected Siblings
- 01-07-2008
- Original Paper
Gepubliceerd in:
- Auteurs
- Robin P. Goin-Kochel
- Carla A. Mazefsky
- Brien P. Riley
- Gepubliceerd in
- Journal of Autism and Developmental Disorders | Uitgave 6/2008
Abstract
Little evidence supports that siblings with autism exhibit the same behaviors; however, some findings suggest that level of functioning shows familial aggregation. We tested this notion among multiplex families participating with the Autism Genetic Resource Exchange (AGRE) Consortium, using scores on the Peabody Picture Vocabulary Test—Third Edition (N = 204 families), the Ravens Colored Progressive Matrices (N = 226 families), and the Vineland Adaptive Behavior Scales (N = 348 families). Intraclass Correlation Coefficients revealed that siblings with autism/autism spectrum disorders (ASD) were more similar on measures of verbal and nonverbal IQ and adaptive functioning than were unrelated children with autism/ASD. Preliminary twin correlations indicated strong genetic effects for some skill domains and the influence of shared environmental factors for others.
- Titel
- Level of Functioning in Autism Spectrum Disorders: Phenotypic Congruence Among Affected Siblings
- Auteurs
-
Robin P. Goin-Kochel
Carla A. Mazefsky
Brien P. Riley
- Publicatiedatum
- 01-07-2008
- Uitgeverij
- Springer US
- Gepubliceerd in
-
Journal of Autism and Developmental Disorders / Uitgave 6/2008
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432 - DOI
- https://doi.org/10.1007/s10803-007-0476-z
Deze inhoud is alleen zichtbaar als je bent ingelogd en de juiste rechten hebt.
Deze inhoud is alleen zichtbaar als je bent ingelogd en de juiste rechten hebt.