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01-03-2012 | Review Article

Left ventricular endocardial pacing in cardiac resynchronisation therapy: Moving from bench to bedside

Auteurs: F. A. Bracke, B. M. van Gelder, L. R. C. Dekker, P. Houthuizen, J. F. ter Woorst, J. A. Teijink

Gepubliceerd in: Netherlands Heart Journal | Uitgave 3/2012

Abstract

In cardiac resynchronisation therapy, failure to implant a left ventricular lead in a coronary sinus branch has been reported in up to 10% of cases. Although surgical insertion of epicardial leads is considered the standard alternative, this is not without morbidity and technical limitations. Endocardial left ventricular pacing can be an alternative as it has been associated with a favourable acute haemodynamic response compared with epicardial pacing in both animal and human studies. In this paper, we discuss left ventricular endocardial pacing and compare it with epicardial surgical implantation. Ease of application and procedural complications and morbidity compare favourably with epicardial surgical techniques. However, with limited experience, the most important concern is the still unknown long-term risk of thromboembolic complications. Therefore, for now endovascular implants should remain reserved for severely symptomatic heart failure patients and patients at high surgical risk of failed coronary sinus implantation.

vorige artikel Long-term outcomes of isolated aortic valve replacement and concomitant AVR and coronary artery bypass grafting

volgende artikel Cardiac surgery and percutaneous intervention in pregnant women with heart disease

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Titel: Left ventricular endocardial pacing in cardiac resynchronisation therapy: Moving from bench to bedside
Auteurs: F. A. Bracke
B. M. van Gelder
L. R. C. Dekker
P. Houthuizen
J. F. ter Woorst
J. A. Teijink
Publicatiedatum: 01-03-2012
Uitgeverij: Bohn Stafleu van Loghum
Gepubliceerd in: Netherlands Heart Journal / Uitgave 3/2012
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI: https://doi.org/10.1007/s12471-011-0210-5

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