Skip to main content
Top
Gepubliceerd in: Netherlands Heart Journal 12/2008

01-12-2008 | case report

Left ventricular assist device as a bridge to recovery in a young woman admitted with peripartum cardiomyopathy

Auteurs: L. Oosterom, N. de Jonge, J. H. Kirkels, C. Klöpping, J. R. Lahpor

Gepubliceerd in: Netherlands Heart Journal | Uitgave 12/2008

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Left ventricular assist devices (LVAD) are an effective therapeutic option for end-stage heart failure patients as a bridge to cardiac transplantation in those who deteriorate despite maximal therapy and when a donor heart is not ready available. In some patients, cardiac recovery has been reported while supported by an LVAD. In this case report, we describe a 29-year-old female who was admitted to our centre because of peripartum cardiomyopathy (PPCM). Despite intensive treatment with intravenous inotropes and intra-aortic balloon counter-pulsation she had a persisting low cardiac index and an LVAD was implanted. In the months following implantation the left ventricular systolic function improved and the left ventricular dimensions normalised. Eventually the LVAD could be ex-planted nine months after implantation. At this moment, three years after explantation, echo-cardiography shows a normal-sized left ventricle and almost completely recovered systolic function. (Neth Heart J 2008;16:426-8).
Literatuur
1.
go back to reference Abboud J, Murad Y, Chen-Scarabelli C, Saravolatz L, Scarabelli T. Peripartum cardiomyopathy: A comprehensive review. Int J Cardiol 2007;118:295-303. Abboud J, Murad Y, Chen-Scarabelli C, Saravolatz L, Scarabelli T. Peripartum cardiomyopathy: A comprehensive review. Int J Cardiol 2007;118:295-303.
2.
go back to reference Amos A, Jaber W, Russell S. Improved outcomes in peripartum cardiomyopathy with contemporary. Am Heart J 2006;152:509-13. Amos A, Jaber W, Russell S. Improved outcomes in peripartum cardiomyopathy with contemporary. Am Heart J 2006;152:509-13.
3.
go back to reference Sliwa K, Fett J, Elkayam U. Peripartum cardiomyopathy. Lancet 2006;368:687-93. Sliwa K, Fett J, Elkayam U. Peripartum cardiomyopathy. Lancet 2006;368:687-93.
4.
go back to reference Hilfiker-Kleiner D, Kaminski K, Podewski E, Bonda T, Schaefer A, Sliwa K, et al. A Cathepsin D-Cleaved 16 kDa Form of Prolactin Mediates Postpartum Cardiomyopathy. Cell 2007;128:589-600. Hilfiker-Kleiner D, Kaminski K, Podewski E, Bonda T, Schaefer A, Sliwa K, et al. A Cathepsin D-Cleaved 16 kDa Form of Prolactin Mediates Postpartum Cardiomyopathy. Cell 2007;128:589-600.
5.
go back to reference Lahpor J, de Jonge N, van Swieten H, Wesenhagen H, Klopping C, Geertman J, et al. Left ventricular assist device as bridge to transplantation in patients with end-stage heart failure / Eight year experience with the implantable HeartMate LVAD. Neth Heart J 2002;10:267-71. Lahpor J, de Jonge N, van Swieten H, Wesenhagen H, Klopping C, Geertman J, et al. Left ventricular assist device as bridge to transplantation in patients with end-stage heart failure / Eight year experience with the implantable HeartMate LVAD. Neth Heart J 2002;10:267-71.
6.
go back to reference De Jonge N, Van Wichen D, Schipper M, Lahpor J, Gmelig-Meyling F, Robles de Medina E, et al. Left Ventricular assist device in end-stage heart failure: persistence of structural myocyte damage after unloading /An immunohistochemical analysis of the contractile myofilaments. J Am Coll Cardiol 2002;39:963-9. De Jonge N, Van Wichen D, Schipper M, Lahpor J, Gmelig-Meyling F, Robles de Medina E, et al. Left Ventricular assist device in end-stage heart failure: persistence of structural myocyte damage after unloading /An immunohistochemical analysis of the contractile myofilaments. J Am Coll Cardiol 2002;39:963-9.
7.
go back to reference Yacoub M. A novel strategy to maximize the efficacy of left ventricular assist devices as a bridge to recovery. Eur Heart J 2001;22:534-40. Yacoub M. A novel strategy to maximize the efficacy of left ventricular assist devices as a bridge to recovery. Eur Heart J 2001;22:534-40.
8.
go back to reference Dipla K, Mattiello J, Jeevanandam V, Houser S, Margulies K. Myocyte Recovery After Mechanical Circulatory Support in Humans With End-Stage Heart Failure. Circulation 1998;97:2316-22. Dipla K, Mattiello J, Jeevanandam V, Houser S, Margulies K. Myocyte Recovery After Mechanical Circulatory Support in Humans With End-Stage Heart Failure. Circulation 1998;97:2316-22.
9.
go back to reference Zafeiridis A, Jeevanandam V, Houser S, Margulies K. Regression of Cellular Hypertrophy After Left Ventricular Assist Device Support. Circulation 1998;98:656-62. Zafeiridis A, Jeevanandam V, Houser S, Margulies K. Regression of Cellular Hypertrophy After Left Ventricular Assist Device Support. Circulation 1998;98:656-62.
10.
go back to reference Mancini D, Beniaminovitz A, Levin H, Catanese K, Flannery M, DiTullio M, et al. Low Incidence of Myocardial Recovery After Left Ventricular Assist Device Implantation in Patients With Chronic Heart Failure. Circulation 1998;98:2383-9. Mancini D, Beniaminovitz A, Levin H, Catanese K, Flannery M, DiTullio M, et al. Low Incidence of Myocardial Recovery After Left Ventricular Assist Device Implantation in Patients With Chronic Heart Failure. Circulation 1998;98:2383-9.
11.
go back to reference Simon M, Kormos R, Murali S, Mair P, Heffernan M, Gorcsan J, et al. Myocardial Recovery Using Ventricular Assist Devices / Prevalence, Clinical Characteristics, and Outcomes. Circulation 2005;112(suppl I):I-32-I-36. Simon M, Kormos R, Murali S, Mair P, Heffernan M, Gorcsan J, et al. Myocardial Recovery Using Ventricular Assist Devices / Prevalence, Clinical Characteristics, and Outcomes. Circulation 2005;112(suppl I):I-32-I-36.
12.
go back to reference Birks E, Tansley P, Hardy J, George R, Bowles C, Burke M, et al. Left Ventricular Assist Device and Drug Therapy for the Reversal of Heart Failure. N Engl J Med 2006;355:1873-84. Birks E, Tansley P, Hardy J, George R, Bowles C, Burke M, et al. Left Ventricular Assist Device and Drug Therapy for the Reversal of Heart Failure. N Engl J Med 2006;355:1873-84.
13.
go back to reference Maybaum S, Mancini D, Xydas S, Starling R, Aaronson K, Pagani F, et al. Cardiac Improvement During Mechanical Circulatory Support / A Prospective Mul ti center Study of the LVAD Working Group. Circulation 2007;115:2497-505. Maybaum S, Mancini D, Xydas S, Starling R, Aaronson K, Pagani F, et al. Cardiac Improvement During Mechanical Circulatory Support / A Prospective Mul ti center Study of the LVAD Working Group. Circulation 2007;115:2497-505.
14.
go back to reference Farrar D, Holman W, McBride L, Kormos R, Icenogle T, Hendry P, et al. Long-Term Follow-up of Thoratec Ventricular Assist Device Bridge-to-Recovery Patients Successfully Removed From Support After Recovery of Ventricular Function. J Heart Lung Transplant 2002;21:516-21. Farrar D, Holman W, McBride L, Kormos R, Icenogle T, Hendry P, et al. Long-Term Follow-up of Thoratec Ventricular Assist Device Bridge-to-Recovery Patients Successfully Removed From Support After Recovery of Ventricular Function. J Heart Lung Transplant 2002;21:516-21.
15.
go back to reference Dandel M, Weng Y, Siniawski H, Potapov E, Lehmkuhl H, Hetzer R. Long-Term Results in Patients With Idiopathic Dilated Cardiomyopathy After Weaning From Left Ventricular Assist Devices. Circulation 2005;112(suppl I):I-37-I-45. Dandel M, Weng Y, Siniawski H, Potapov E, Lehmkuhl H, Hetzer R. Long-Term Results in Patients With Idiopathic Dilated Cardiomyopathy After Weaning From Left Ventricular Assist Devices. Circulation 2005;112(suppl I):I-37-I-45.
Metagegevens
Titel
Left ventricular assist device as a bridge to recovery in a young woman admitted with peripartum cardiomyopathy
Auteurs
L. Oosterom
N. de Jonge
J. H. Kirkels
C. Klöpping
J. R. Lahpor
Publicatiedatum
01-12-2008
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Netherlands Heart Journal / Uitgave 12/2008
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI
https://doi.org/10.1007/BF03086192

Andere artikelen Uitgave 12/2008

Netherlands Heart Journal 12/2008 Naar de uitgave