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Gepubliceerd in: Journal of Autism and Developmental Disorders 3/2012

01-03-2012 | Original Paper

Lack of Correlation Between Metallic Elements Analyzed in Hair by ICP-MS and Autism

Auteurs: Giuseppe De Palma, Simona Catalani, Anna Franco, Maurizio Brighenti, Pietro Apostoli

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 3/2012

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Abstract

A cross-sectional case–control study was carried out to evaluate the concentrations of metallic elements in the hair of 44 children with diagnosis of autism and 61 age-balanced controls. Unadjusted comparisons showed higher concentrations of molybdenum, lithium and selenium in autistic children. Logistic regression analysis confirmed the role of risk factor for male gender and showed a slight association with molybdenum concentrations. Unconventional chelation and vitamin-mineral supplementation were ineffective on elemental hair concentrations. A meta-analysis including the present and previous similar studies excluded any association of autism with hair concentrations of mercury, cadmium, selenium, lithium and copper. A slight association was found for lead only, but it was very weak, as strictly dependent on the worst data from one study.
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Metagegevens
Titel
Lack of Correlation Between Metallic Elements Analyzed in Hair by ICP-MS and Autism
Auteurs
Giuseppe De Palma
Simona Catalani
Anna Franco
Maurizio Brighenti
Pietro Apostoli
Publicatiedatum
01-03-2012
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 3/2012
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-011-1245-6

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