Skip to main content
Top

Tip

Swipe om te navigeren naar een ander hoofdstuk

2006 | OriginalPaper | Hoofdstuk

Kunnen de klassieke NSAID‘s cardiovasculaire problemen veroorzaken?

Auteur : dr. J. Riezebos

Gepubliceerd in: Vademecum permanente nascholing huisartsen

Uitgeverij: Bohn Stafleu van Loghum

share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Samenvatting

De groep van prostaglandinesynthetaseremmers, beter bekend als ‘Non-Steroidal Anti-Inflammatory Drugs (NSAID’s) kan worden onderverdeeld in middelen die selectief het cyclo-oxygenase-2 remmen (COX-2-remmers, zoals celecoxib en etoricoxib) en middelen die naast het COX-2 ook in wisselende mate het COX-1 remmen. Deze laatste groep, met vertegenwoordigers als het naproxen en diclofenac, wordt ook wel aangeduid als de non-selectieve of klassieke NSAID’s. Van een aantal van de selectieve COX-2-remmers is aangetoond dat ze het risico op hart- en vaatziekten verhogen.
Literatuur
go back to reference Bresalier RS, Sandler RS, Quan H, et al. Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med 2005; 352: 1092-102. Bresalier RS, Sandler RS, Quan H, et al. Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med 2005; 352: 1092-102.
go back to reference Jones SC. Relative Thromboembolic Risks Associated with COX2 Inhibitors. Ann Pharmacother 2005; 39: 1249-59. Jones SC. Relative Thromboembolic Risks Associated with COX2 Inhibitors. Ann Pharmacother 2005; 39: 1249-59.
go back to reference Hippisley-Cox J, Coupland C. Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis. Br Med J 2005; 330: 1366-72. Hippisley-Cox J, Coupland C. Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis. Br Med J 2005; 330: 1366-72.
go back to reference Johnson SP, Larsson H, Tarone RE, et al. Risk of hospitalization for myocardial infarction among users of rofecoxib, celecoxib and other NSAID’s. Arch Intern Med 2005;165: 978-84. Johnson SP, Larsson H, Tarone RE, et al. Risk of hospitalization for myocardial infarction among users of rofecoxib, celecoxib and other NSAID’s. Arch Intern Med 2005;165: 978-84.
go back to reference Mamdani M, Rochon P, Juurlink DN, et al. Effect of selective cyclooxygenase 2 inhibitors and naproxen on short-term risk of acute myocardial infarction in the elderly. Arch Intern Med 2003; 163: 481-86. Mamdani M, Rochon P, Juurlink DN, et al. Effect of selective cyclooxygenase 2 inhibitors and naproxen on short-term risk of acute myocardial infarction in the elderly. Arch Intern Med 2003; 163: 481-86.
go back to reference Graham D, Campen D, Hui R, et al. Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study. Lancet 2005; 365: 475-81. Graham D, Campen D, Hui R, et al. Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study. Lancet 2005; 365: 475-81.
go back to reference Solomon DH, Avorn J, Sturmer T, et al. Cardiovascular outcomes in new users of coxibs and nonsteroidal antiinflammatory drugs. Arthritis & Rheumatism 2006; 54: 1378-89. Solomon DH, Avorn J, Sturmer T, et al. Cardiovascular outcomes in new users of coxibs and nonsteroidal antiinflammatory drugs. Arthritis & Rheumatism 2006; 54: 1378-89.
go back to reference Kearney PM, Baigent C, Godwin J, et al. Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials. Br Med J 2006; 332: 1302-08. Kearney PM, Baigent C, Godwin J, et al. Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials. Br Med J 2006; 332: 1302-08.
Metagegevens
Titel
Kunnen de klassieke NSAID‘s cardiovasculaire problemen veroorzaken?
Auteur
dr. J. Riezebos
Copyright
2006
Uitgeverij
Bohn Stafleu van Loghum
DOI
https://doi.org/10.1007/978-90-313-8808-0_88